ID A0A369SFE1_9METZ Unreviewed; 158 AA.
AC A0A369SFE1;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=Protein Dr1 {ECO:0000256|ARBA:ARBA00018742};
DE AltName: Full=Down-regulator of transcription 1 {ECO:0000256|ARBA:ARBA00032651};
DE AltName: Full=Negative cofactor 2-beta {ECO:0000256|ARBA:ARBA00030451};
GN ORFNames=TrispH2_002518 {ECO:0000313|EMBL:RDD45194.1};
OS Trichoplax sp. H2.
OC Eukaryota; Metazoa; Placozoa; Uniplacotomia; Trichoplacea; Trichoplacidae;
OC Trichoplax.
OX NCBI_TaxID=287889 {ECO:0000313|EMBL:RDD45194.1, ECO:0000313|Proteomes:UP000253843};
RN [1] {ECO:0000313|EMBL:RDD45194.1, ECO:0000313|Proteomes:UP000253843}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Panama {ECO:0000313|EMBL:RDD45194.1,
RC ECO:0000313|Proteomes:UP000253843};
RC TISSUE=Whole clonal animals {ECO:0000313|EMBL:RDD45194.1};
RX PubMed=30042472; DOI=10.1038/s41598-018-29400-y;
RA Kamm K., Osigus H.J., Stadler P.F., DeSalle R., Schierwater B.;
RT "Trichoplax genomes reveal profound admixture and suggest stable wild
RT populations without bisexual reproduction.";
RL Sci. Rep. 8:11168-11168(2018).
CC -!- SIMILARITY: Belongs to the NC2 beta/DR1 family.
CC {ECO:0000256|ARBA:ARBA00009245}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDD45194.1}.
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DR EMBL; NOWV01000018; RDD45194.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A369SFE1; -.
DR STRING; 287889.A0A369SFE1; -.
DR Proteomes; UP000253843; Unassembled WGS sequence.
DR GO; GO:0017054; C:negative cofactor 2 complex; IEA:InterPro.
DR GO; GO:0140223; F:general transcription initiation factor activity; IEA:InterPro.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IEA:InterPro.
DR Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR InterPro; IPR003958; CBFA_NFYB_domain.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR042225; Ncb2.
DR PANTHER; PTHR46138; PROTEIN DR1; 1.
DR PANTHER; PTHR46138:SF1; PROTEIN DR1; 1.
DR Pfam; PF00808; CBFD_NFYB_HMF; 1.
DR SUPFAM; SSF47113; Histone-fold; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000253843}.
FT DOMAIN 10..73
FT /note="Transcription factor CBF/NF-Y/archaeal histone"
FT /evidence="ECO:0000259|Pfam:PF00808"
FT COILED 113..149
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 158 AA; 18003 MW; 23D2DDDC2FC0E98F CRC64;
MTDSDEESAN LPRSTIQKFI KEVVPGVRVS NDAKDLISNI CNEFVHMVSS ESNSICSQKN
KKTIFPEHVI EALKNLGFEG YVGELKKVLG DLKTEKEERK KCSKKLEKSG FSLTELEKQQ
KELFEKAKEE QAREELMEWN QLVEEEKAAK HAQSSKAL
//
