ID A0A369SFF4_9METZ Unreviewed; 900 AA.
AC A0A369SFF4;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=NB-ARC domain-containing protein {ECO:0000259|Pfam:PF00931};
GN ORFNames=TrispH2_003549 {ECO:0000313|EMBL:RDD45529.1};
OS Trichoplax sp. H2.
OC Eukaryota; Metazoa; Placozoa; Uniplacotomia; Trichoplacea; Trichoplacidae;
OC Trichoplax.
OX NCBI_TaxID=287889 {ECO:0000313|EMBL:RDD45529.1, ECO:0000313|Proteomes:UP000253843};
RN [1] {ECO:0000313|EMBL:RDD45529.1, ECO:0000313|Proteomes:UP000253843}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Panama {ECO:0000313|EMBL:RDD45529.1,
RC ECO:0000313|Proteomes:UP000253843};
RC TISSUE=Whole clonal animals {ECO:0000313|EMBL:RDD45529.1};
RX PubMed=30042472; DOI=10.1038/s41598-018-29400-y;
RA Kamm K., Osigus H.J., Stadler P.F., DeSalle R., Schierwater B.;
RT "Trichoplax genomes reveal profound admixture and suggest stable wild
RT populations without bisexual reproduction.";
RL Sci. Rep. 8:11168-11168(2018).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDD45529.1}.
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DR EMBL; NOWV01000015; RDD45529.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A369SFF4; -.
DR Proteomes; UP000253843; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR22845; APOPTOTIC PROTEASE-ACTIVATING FACTOR 1; 1.
DR PANTHER; PTHR22845:SF5; APOPTOTIC PROTEASE-ACTIVATING FACTOR 1; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Apoptosis {ECO:0000256|ARBA:ARBA00022703};
KW Reference proteome {ECO:0000313|Proteomes:UP000253843}.
FT DOMAIN 493..808
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
FT REGION 443..464
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 900 AA; 103284 MW; A3BDDD5731585067 CRC64;
MANQQEAGKW PEDFDDSQFK NGSKIKQFLI TFIENFISVL QEMSNMLELQ IELKSGIIAD
STSQFLDGIK SFLLAVSHDG LYNIAKGNEI IQRLIDEITE RRDRKFIKKI IDRLTPNKDS
IKLAISIMAC DLVRIYEQQI SIISGYSDNY YVKKFANDMV KVIIRYILNE EDSPPEKPTD
IAKFVIPCLF NPNFAKKKWF KIKKGSELEI VLQENGNLKK INSPDLIINT GIRVKVNNSF
KCYDLSHGGK IALYGFRQLS FFSIGNHKDI VNGINDITHQ ININDQSLYQ YKSKLSGNLD
MESFIHYAEQ VLNVVTQKDR FEITATVNDD QINVITTLLT EDISNLINDK MDAFKIYLKE
AFGKEMKEMK EILEKIAKYQ DLITNEKFIL TNSIEEISKA FNIHTQKMIE NLEKAGTERK
QILALNLRIE QKLDGLVNQI QSNPTDASGL NQPNRNISQE SDSKDTTVIS KPLLKDLLKN
FPIVPDSHYI RREKWITKIC DQLKEIGTND GQVLIYGSPG IGKTVAVAQA VERSVIELGH
FQSYKAYWLD IEYFIIQKEN GILVIAVANS MTKILTYCYS KEKHYNFEFV LDLKKISNLW
SSQRLAFITD KSQIHIYDKC KIQLLQVIQS PINDEYSEIS GKINEDQLAE KLKSLYQILS
GSKVFSNELP SILDNINRLF EEDKKVGNNL FVFDDIWHPS YYNYFKFAKK SIATSREINP
NNKLQPSIEI SEGFTDIEVR EVFKKYEKIE NAEICKEEPW IDDIIIASGG LPLAIGLIGG
LGLRTNEQWK NALNSIRDAK CPVKIPNYEN NLWGTVELSI KNLGEHEQKF RQLGAFKYPK
VSIDSITSLW QCEKEVGQSI LRKFHSKSLL KSLDYESSSS DNEVERAFID PILVFNVIKN
//
