ID A0A369SHV1_9METZ Unreviewed; 687 AA.
AC A0A369SHV1;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Kanadaptin {ECO:0000313|EMBL:RDD46426.1};
GN ORFNames=TrispH2_002011 {ECO:0000313|EMBL:RDD46426.1};
OS Trichoplax sp. H2.
OC Eukaryota; Metazoa; Placozoa; Uniplacotomia; Trichoplacea; Trichoplacidae;
OC Trichoplax.
OX NCBI_TaxID=287889 {ECO:0000313|EMBL:RDD46426.1, ECO:0000313|Proteomes:UP000253843};
RN [1] {ECO:0000313|EMBL:RDD46426.1, ECO:0000313|Proteomes:UP000253843}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Panama {ECO:0000313|EMBL:RDD46426.1,
RC ECO:0000313|Proteomes:UP000253843};
RC TISSUE=Whole clonal animals {ECO:0000313|EMBL:RDD46426.1};
RX PubMed=30042472; DOI=10.1038/s41598-018-29400-y;
RA Kamm K., Osigus H.J., Stadler P.F., DeSalle R., Schierwater B.;
RT "Trichoplax genomes reveal profound admixture and suggest stable wild
RT populations without bisexual reproduction.";
RL Sci. Rep. 8:11168-11168(2018).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDD46426.1}.
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DR EMBL; NOWV01000008; RDD46426.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A369SHV1; -.
DR STRING; 287889.A0A369SHV1; -.
DR Proteomes; UP000253843; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd19856; DSRM_Kanadaptin; 1.
DR CDD; cd22677; FHA_Kanadaptin; 1.
DR Gene3D; 2.60.200.20; -; 1.
DR Gene3D; 3.30.160.20; -; 1.
DR InterPro; IPR014720; dsRBD_dom.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR PANTHER; PTHR23308:SF53; KANADAPTIN-RELATED; 1.
DR PANTHER; PTHR23308; NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1; 1.
DR Pfam; PF00035; dsrm; 1.
DR Pfam; PF00498; FHA; 1.
DR SMART; SM00358; DSRM; 1.
DR SMART; SM00240; FHA; 1.
DR SUPFAM; SSF54768; dsRNA-binding domain-like; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR PROSITE; PS50137; DS_RBD; 1.
DR PROSITE; PS50006; FHA_DOMAIN; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000253843};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00266}.
FT DOMAIN 120..177
FT /note="FHA"
FT /evidence="ECO:0000259|PROSITE:PS50006"
FT DOMAIN 288..361
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT REGION 1..75
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 230..252
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 505..548
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 567..687
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 412..446
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 10..63
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 523..543
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 616..630
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 631..658
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 687 AA; 77369 MW; E8F6C6912F4CB7DC CRC64;
MEDQQHAEDI ATHGPSNAQE DTSQKEKFAS PLPISNKTAK SNEPSTASNE TAVASTCNDS
TSHHGSKENN KSSLTRDKII KNIPYDEPSW SGIADKNYTL EVLKNGCIVD IWKLNDKAYY
IFGRSPVCDF VLDHPSVSRC HAVLQFHKYN HDDAGKVGFY MYDLASTHGS QINKSPVEPR
RYYRLRVGHM IKFGSSSRVY ILQGPSDDQE EEIYVSDSRK AVKQIMNAEE VEEWKQKQEK
DQKGDSRKED KNDVTWGIDF GVEEEDADID IIEKARTSHD DDSYFVKDPK KALRHFFETA
GVTMEYEVCE SGTPRNRTYQ ARIKLPVETS EGSCIYGEGT AEKKKDAVVA CALDGCRILE
AYGMLRSSVS IKRKRKNWED NDYYDSDEDN FLDRTGDLEN KRIARMRRAG KITEEAETFQ
SLSLKLKEIQ DEMNRLRSKL NSAKGQQQTS EADSLDAFMN NVSNTLDARA ITSIRLHLSD
LRKKEEKLIK LVEIARPAEL PEYLQLKKTT DSKGLPASPN RKPDGTDEAD KGTPVDLKSK
VNEKPSVKVS SVAQNVSLKA KGVQFLGAHP SKMTGPKVRD DDDDDIVEFD SESDSEEPKK
GATSMETNKT VDDARQYSVR LPDRELSLKE VEITTINQEL DDSSNNSRNA GPSQPSQRND
DDECIDWLPP EDQFGDGKTS LNTKLGY
//
