ID A0A369SIV1_9METZ Unreviewed; 854 AA.
AC A0A369SIV1;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Prestin {ECO:0000313|EMBL:RDD46837.1};
GN ORFNames=TrispH2_001138 {ECO:0000313|EMBL:RDD46837.1};
OS Trichoplax sp. H2.
OC Eukaryota; Metazoa; Placozoa; Uniplacotomia; Trichoplacea; Trichoplacidae;
OC Trichoplax.
OX NCBI_TaxID=287889 {ECO:0000313|EMBL:RDD46837.1, ECO:0000313|Proteomes:UP000253843};
RN [1] {ECO:0000313|EMBL:RDD46837.1, ECO:0000313|Proteomes:UP000253843}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Panama {ECO:0000313|EMBL:RDD46837.1,
RC ECO:0000313|Proteomes:UP000253843};
RC TISSUE=Whole clonal animals {ECO:0000313|EMBL:RDD46837.1};
RX PubMed=30042472; DOI=10.1038/s41598-018-29400-y;
RA Kamm K., Osigus H.J., Stadler P.F., DeSalle R., Schierwater B.;
RT "Trichoplax genomes reveal profound admixture and suggest stable wild
RT populations without bisexual reproduction.";
RL Sci. Rep. 8:11168-11168(2018).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU362052}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU362052}.
CC -!- SIMILARITY: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
CC {ECO:0000256|RuleBase:RU362052}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDD46837.1}.
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DR EMBL; NOWV01000006; RDD46837.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A369SIV1; -.
DR STRING; 287889.A0A369SIV1; -.
DR Proteomes; UP000253843; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008509; F:monoatomic anion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0098661; P:inorganic anion transmembrane transport; IEA:UniProtKB-UniRule.
DR CDD; cd07042; STAS_SulP_like_sulfate_transporter; 1.
DR Gene3D; 3.30.750.24; STAS domain; 1.
DR InterPro; IPR011547; SLC26A/SulP_dom.
DR InterPro; IPR001902; SLC26A/SulP_fam.
DR InterPro; IPR002645; STAS_dom.
DR InterPro; IPR036513; STAS_dom_sf.
DR NCBIfam; TIGR00815; sulP; 1.
DR PANTHER; PTHR11814:SF257; ANION TRANSPORTER SULP-7D; 1.
DR PANTHER; PTHR11814; SULFATE TRANSPORTER; 1.
DR Pfam; PF01740; STAS; 1.
DR Pfam; PF00916; Sulfate_transp; 1.
DR SUPFAM; SSF52091; SpoIIaa-like; 1.
DR PROSITE; PS50801; STAS; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362052};
KW Reference proteome {ECO:0000313|Proteomes:UP000253843};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362052};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362052}; Transport {ECO:0000256|RuleBase:RU362052}.
FT TRANSMEM 163..183
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 195..223
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 300..320
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 370..398
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 410..430
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 468..487
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 499..519
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 539..557
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 564..584
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 596..626
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT DOMAIN 650..822
FT /note="STAS"
FT /evidence="ECO:0000259|PROSITE:PS50801"
SQ SEQUENCE 854 AA; 94252 MW; 4E8086139A5CAC84 CRC64;
MSNRLHAMRK KVNENVRVAN ANQNGAEASD QAIQRTVRTK KVRCYLSHPE GLPIKSFLNE
NTRNGSPNQL LSVDLTDRRM RRKNPNEDEE EINIATSVVR PVYTESQFDE GFEPRPPRAK
SSLDRLGLRN CFKCSCMEFL VSFIPILSWL PKYDRRQNLG GDIAAGLTVG IMQIPQGLAY
AMLTTLQPIT GLYTSFFPVI IYTLFGTSRH ISIGTFAVIS LLVAEGVQNS INSQAYQAAL
TSPTSTVNIL NTTTLVTTKD SDVTTVISTI AAATGVDNVT IATSSNTFVT TTNPQDLQKL
GAAVALTFLV GVIMLLMGLL RLGFVTIYLS DPLVSGFTCG AACHVFTSQI KHVFGISLPR
YSGAFVIPKT YYYLFANISQ TNWISLVMGI LCIISLLVMK KLNEKYKNKL PFPIPAELLV
VIAGTLASYL GKLGDKPHNI KIIGNIPTGL PPPSAPPFEL MGTMFRDAIT ISVVSFAVSI
SLVKVFQKKH GYPTDSNQEL IAYGLSNIFG SFFSCFVASG SLSRSAVQDN LGGKTQVTSL
VSCFIVLIVL LLIAPAFQFL PHTILGSIVL VALKGLLMQV THFFQLWRIS VIDAIIWMVT
FGSVFLLGVD IGLLIGVAVA LLTVIFRTSR PYYCLLGRIP NTDLYRDIKK YAAVEEVPGV
KMFRFESSLY FANTEHFKYT LYEITGLCPT DRTAMELQYD LRNRIVTSGN LEYLQHSNMD
TANNSYFGAE DTGITISDSS NIDPNAYPIH TVIVDCSTFN YIDSVAVSTL SQIALEYKVE
DIKFLLAGCK WHVRKMLENG GFVAKCGKNS LFVTLHDAAV YAVDEYNVKV LQRKHELEIE
NRGTDLPALF ETRV
//
