ID A0A369SLJ8_9METZ Unreviewed; 915 AA.
AC A0A369SLJ8;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Peroxidasin-like protein {ECO:0000313|EMBL:RDD47746.1};
GN ORFNames=TrispH2_000548 {ECO:0000313|EMBL:RDD47746.1};
OS Trichoplax sp. H2.
OC Eukaryota; Metazoa; Placozoa; Uniplacotomia; Trichoplacea; Trichoplacidae;
OC Trichoplax.
OX NCBI_TaxID=287889 {ECO:0000313|EMBL:RDD47746.1, ECO:0000313|Proteomes:UP000253843};
RN [1] {ECO:0000313|EMBL:RDD47746.1, ECO:0000313|Proteomes:UP000253843}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Panama {ECO:0000313|EMBL:RDD47746.1,
RC ECO:0000313|Proteomes:UP000253843};
RC TISSUE=Whole clonal animals {ECO:0000313|EMBL:RDD47746.1};
RX PubMed=30042472; DOI=10.1038/s41598-018-29400-y;
RA Kamm K., Osigus H.J., Stadler P.F., DeSalle R., Schierwater B.;
RT "Trichoplax genomes reveal profound admixture and suggest stable wild
RT populations without bisexual reproduction.";
RL Sci. Rep. 8:11168-11168(2018).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDD47746.1}.
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DR EMBL; NOWV01000001; RDD47746.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A369SLJ8; -.
DR STRING; 287889.A0A369SLJ8; -.
DR Proteomes; UP000253843; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004601; F:peroxidase activity; IEA:InterPro.
DR GO; GO:0006979; P:response to oxidative stress; IEA:InterPro.
DR Gene3D; 1.10.640.10; Haem peroxidase domain superfamily, animal type; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR019791; Haem_peroxidase_animal.
DR InterPro; IPR010255; Haem_peroxidase_sf.
DR InterPro; IPR037120; Haem_peroxidase_sf_animal.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR11475; OXIDASE/PEROXIDASE; 1.
DR PANTHER; PTHR11475:SF58; PEROXIDASIN; 1.
DR Pfam; PF03098; An_peroxidase; 1.
DR Pfam; PF07679; I-set; 1.
DR PRINTS; PR00457; ANPEROXIDASE.
DR SMART; SM00409; IG; 1.
DR SMART; SM00408; IGc2; 1.
DR SUPFAM; SSF48113; Heme-dependent peroxidases; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
DR PROSITE; PS50292; PEROXIDASE_3; 1.
PE 4: Predicted;
KW Heme {ECO:0000256|PIRSR:PIRSR619791-2};
KW Iron {ECO:0000256|PIRSR:PIRSR619791-2};
KW Metal-binding {ECO:0000256|PIRSR:PIRSR619791-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000253843};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 111..208
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT BINDING 665
FT /ligand="heme b"
FT /ligand_id="ChEBI:CHEBI:60344"
FT /ligand_part="Fe"
FT /ligand_part_id="ChEBI:CHEBI:18248"
FT /note="axial binding residue"
FT /evidence="ECO:0000256|PIRSR:PIRSR619791-2"
SQ SEQUENCE 915 AA; 104452 MW; 6EA1939DE13F647C CRC64;
MLQIVRRARV KLSQSNRPTC YKPDSLNGKA ITELKEINFE YCPFTSDINN DFWGPSHAFH
CQRLDTSRGI ENFYRRLPAM KQHFVSHGGR IRVLSEDDKR NQCLQYGGFY PWADDYNSRF
SKLQFVKRPR NIQVREGEHS LFLPCSARGK PSPVMVWYKN NQQIINTGHI KIEKNGLRIF
SIGVADAGRY TCTARNRNDL ISAELIVKVA RARPRTDYID DGVILDSVRL AVKYVDEAIA
TTKQTLFSKT IKRTPAALLM SLRYPNPDAS KLVARHAIFE TSLSILASRL DISPSSFAHL
SKILSPRHIA MIANLTGCNQ QMYKQPDCSN LCYHMKYRSY DGSCNNLQYP SRGTTLTQLV
RLLRPAYEDD LNEPIGWDTK KLVRPPARLV SQNIVSTLSI VDDGSFSHML MQWGQFIDHD
ISLIVGSSSR STYKSRIPCD KLCRNDPPCF PIYPAPNDKR VPKDACIEFT RSSAACGTGL
SSIFFNELLP RQQLNQVTSY IDGSTIYGSS KEEVRRLRDL DHDEGLLKEG IKISPRKRLL
PFHNGAPVDC QIDDQDQSVP CFLAGDIRVN EQLALTAMHT IWMREHNRIA SKLKKLNYNW
NGEKIFQEAR KIVIAEIQHI TFHNFLPKIL GQEGLKLLGK YQNYQPDADA TLINSFATAA
FRFGHGTVRP TLFRLNELYQ PIPQGHLRLR DAFFAPSRLL HEGGIDPILR GLIFFPSKLS
RSDRMLNEEL TDHLFGMAHE IALDLASLNI QRGRDHGLPS YNHYRVMCNL PAATHFHELS
NEITNRTILN KLEKAYQHPN NIDLWVGAMA EDALFGGRVG PTFACLIALQ FNRLRAGDRF
WYENKAQFSP NQLTQIKRSS LARILCDNGD NITRVQNDVF LNVYYEGDIT DCDAIPSIDL
KHWYECQDGK QKKKF
//
