ID A0A369SLR4_9METZ Unreviewed; 1042 AA.
AC A0A369SLR4;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=AP-3 complex subunit delta {ECO:0000256|PIRNR:PIRNR037092};
GN ORFNames=TrispH2_000280 {ECO:0000313|EMBL:RDD47424.1};
OS Trichoplax sp. H2.
OC Eukaryota; Metazoa; Placozoa; Uniplacotomia; Trichoplacea; Trichoplacidae;
OC Trichoplax.
OX NCBI_TaxID=287889 {ECO:0000313|EMBL:RDD47424.1, ECO:0000313|Proteomes:UP000253843};
RN [1] {ECO:0000313|EMBL:RDD47424.1, ECO:0000313|Proteomes:UP000253843}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Panama {ECO:0000313|EMBL:RDD47424.1,
RC ECO:0000313|Proteomes:UP000253843};
RC TISSUE=Whole clonal animals {ECO:0000313|EMBL:RDD47424.1};
RX PubMed=30042472; DOI=10.1038/s41598-018-29400-y;
RA Kamm K., Osigus H.J., Stadler P.F., DeSalle R., Schierwater B.;
RT "Trichoplax genomes reveal profound admixture and suggest stable wild
RT populations without bisexual reproduction.";
RL Sci. Rep. 8:11168-11168(2018).
CC -!- SUBUNIT: Adaptor protein complex 3 (AP-3) is a heterotetramer.
CC {ECO:0000256|PIRNR:PIRNR037092}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus {ECO:0000256|PIRNR:PIRNR037092}.
CC -!- SIMILARITY: Belongs to the adaptor complexes large subunit family.
CC {ECO:0000256|ARBA:ARBA00006613, ECO:0000256|PIRNR:PIRNR037092}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDD47424.1}.
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DR EMBL; NOWV01000003; RDD47424.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A369SLR4; -.
DR STRING; 287889.A0A369SLR4; -.
DR Proteomes; UP000253843; Unassembled WGS sequence.
DR GO; GO:0030123; C:AP-3 adaptor complex; IEA:InterPro.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR017105; AP3_complex_dsu.
DR InterPro; IPR010474; AP3D_dom_metazoa.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR002553; Clathrin/coatomer_adapt-like_N.
DR PANTHER; PTHR22781:SF12; AP-3 COMPLEX SUBUNIT DELTA-1; 1.
DR PANTHER; PTHR22781; DELTA ADAPTIN-RELATED; 1.
DR Pfam; PF01602; Adaptin_N; 1.
DR Pfam; PF06375; AP3D1; 2.
DR PIRSF; PIRSF037092; AP3_complex_delta; 1.
DR SMART; SM01354; BLVR; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Golgi apparatus {ECO:0000256|PIRNR:PIRNR037092};
KW Protein transport {ECO:0000256|PIRNR:PIRNR037092};
KW Reference proteome {ECO:0000313|Proteomes:UP000253843};
KW Transport {ECO:0000256|PIRNR:PIRNR037092}.
FT DOMAIN 651..771
FT /note="AP-3 complex subunit delta"
FT /evidence="ECO:0000259|SMART:SM01354"
FT REGION 662..687
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 705..883
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 904..961
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 750..766
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 778..804
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 857..877
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 904..920
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 929..943
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1042 AA; 117360 MW; 376715BC4B7352B2 CRC64;
MFEKNLNDLV RGIRANKSNE AKYIAQCIEE IKHELRQDNT NVKANAICKL IYLQMFGYDI
SWAAFNVIEV MSSTKFTHKR IGYLASSQCF TEDMDILTLT TNLIRKDFSS QNQYDAAVTL
NGLSCFVSAD LARDLANDVI TLLASTKPYI RKRAIIVLYK IFLKFPEALR PAYPRLKAKL
DDPEPSVQSA AVNVICELAR KNPQNYLSLA PIFFKLMTNS TNNWMLIKII KLFAALTPLE
PRLGKKLIEP LTNLIHSTSA MSLLYECINT VIAVLLAFTS MPNHSSSVQL CVSKLRLLIE
DADQNLKYLG LLAMSKILKA HPKAVQAHKD MILRCLDDKD ESIKLRALDL LSGMISKKNL
VEIVKKLMRH IETTESTSYR DELLSKIIHI CSQSNYQYVA DFEWYISVLV ELAQVDGIHH
GSLVATQLLD VTVRVKGIRG FSVQQMTMLL ENSKLMGITA QGSSTGDVFF AAAWIVGEFS
EHLSDLRSIM HIFLQPRATS LPPPVQAVIV HNILKLYSRI YLKAENDNDQ DTIAEVTQML
IDQLPMFGES SDLEVQERAC CAIQMLKYIQ KIRDKGLTVT DEVREMFAGE LNPVATKAQK
KVPVPEGLNL DIWINDPPSD SSDDELNNDA MFVTEEDHNI SNIQGIKYPK VDEDELKKRR
EARKLEQENN PYYIKGNTKS KELEGPDIND IPVASLDLTV PLKVPGKESV KKSKRKKKKG
RKHDTEEDND NVVATHDVNT DMGEMPEGAV STDDEEKEKK DPYNFLNVDL EKPLTEADMI
PVPKHHEASN KPADDEDTET AKNKLKKTKK KKDKEKTKGK KSSNSKKDKS SKRKKGIDIV
PPNDTEEAVE ANLISDETVP ALTTPELSQN SKSTGEKELE SVTNKMDDIN FWLTNNDTSS
AGHITIPDAT VNPANTVENN DVNEKSRKGK KDKKRKKKGK KVKPSTESRL LEMADQPSEQ
TDLVEVTSDQ PEKYASSYIL LGESEDLKMT CKTQINPQFR NQVIVSIIFS NKTDFIISSL
EFNVLDTLNT KLQRPASSIY IH
//
