ID A0A369SPQ9_9METZ Unreviewed; 911 AA.
AC A0A369SPQ9;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Exostosin-like 3 {ECO:0000313|EMBL:RDD47513.1};
GN ORFNames=TrispH2_000827 {ECO:0000313|EMBL:RDD47513.1};
OS Trichoplax sp. H2.
OC Eukaryota; Metazoa; Placozoa; Uniplacotomia; Trichoplacea; Trichoplacidae;
OC Trichoplax.
OX NCBI_TaxID=287889 {ECO:0000313|EMBL:RDD47513.1, ECO:0000313|Proteomes:UP000253843};
RN [1] {ECO:0000313|EMBL:RDD47513.1, ECO:0000313|Proteomes:UP000253843}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Panama {ECO:0000313|EMBL:RDD47513.1,
RC ECO:0000313|Proteomes:UP000253843};
RC TISSUE=Whole clonal animals {ECO:0000313|EMBL:RDD47513.1};
RX PubMed=30042472; DOI=10.1038/s41598-018-29400-y;
RA Kamm K., Osigus H.J., Stadler P.F., DeSalle R., Schierwater B.;
RT "Trichoplax genomes reveal profound admixture and suggest stable wild
RT populations without bisexual reproduction.";
RL Sci. Rep. 8:11168-11168(2018).
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004648}; Single-pass type II membrane protein
CC {ECO:0000256|ARBA:ARBA00004648}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 47 family.
CC {ECO:0000256|ARBA:ARBA00010271}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDD47513.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; NOWV01000002; RDD47513.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A369SPQ9; -.
DR STRING; 287889.A0A369SPQ9; -.
DR Proteomes; UP000253843; Unassembled WGS sequence.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016757; F:glycosyltransferase activity; IEA:InterPro.
DR GO; GO:0006486; P:protein glycosylation; IEA:InterPro.
DR InterPro; IPR004263; Exostosin.
DR InterPro; IPR040911; Exostosin_GT47.
DR InterPro; IPR015338; GT64.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR48261; ACETYLGLUCOSAMINYLTRANSFERASE; 1.
DR PANTHER; PTHR48261:SF2; EXOSTOSIN-1-LIKE; 1.
DR Pfam; PF03016; Exostosin; 1.
DR Pfam; PF09258; Glyco_transf_64; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000253843};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 28..47
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 201..490
FT /note="Exostosin GT47"
FT /evidence="ECO:0000259|Pfam:PF03016"
FT DOMAIN 640..895
FT /note="Glycosyl transferase 64"
FT /evidence="ECO:0000259|Pfam:PF09258"
SQ SEQUENCE 911 AA; 105596 MW; 2B185BECB04562A2 CRC64;
MTRSGYSGSL LTYRVGKTCA HSFKRGRVFY LLVLIALLSI SLIISLYRNN NCTPCQHHFQ
ADKCQQNIDC CLRLEARVKR LRSIKVAIQN EIKVLSSTRF QLDRDVAELK LLKLARPNTN
NVNGRDKRCQ CKKDGDVLKK TIQHQRSQIS LLNELLTNLD RPSYNNKLQL SPCKPIKIDL
TWKSDATKVL RDCNLQRCFH YDRCPLTKIF NAYIYPSRYH VNSVLANQSF QSIPFLTRNA
TAACVYVVIV NSTAATRRDL EGYLHSLPYW HRYGRNHLLV DIGWTIQKLL SINTGYAMLA
GSNFANFVPR MNFDIIIPPM QLFPQYHGKL IDSGPRRPFT ISKQRQYLLH FRGQIIANNS
INLLLRSQLS NISNIAKVMG NKVDIQTQCK KVNKLYYHKF EWSLCSGNVD KQLRESTFSL
IILHNGPCIS TLTRLMHALA SGTIPIFITD HSIKMTLVQM LPFAEYIDWN LAGIMLPLTR
LPEMTAVLMA ISNSDILKKR SHCQFIYHTY FSNSENVLHA TLALLRTRLH LPAYPVDTFI
QDQFSNSKYS LNNVINIDKS MPSIPSTSYT RNYSTNFYNA WNKAPGPYWL YPFTADNSFL
PTDSQFNGFG KGFQPINNGG TATGKMFSKH LGGNYPLEQF TIIILTHNRP NILRQRLINL
SRLLYLNKII VVWNEYNKYA KHFQWPHSDI PIYVFKSKRN SLNDRFFPFN AVETEAVLSL
DDDVDLNADE IDFAFRRVFA ISNKLFLFES VWRESRDRIV GFPARHHTWN KLTNRWSYDS
NKTCQLSMVL TGAAFIHKYY LFLYTFTMPE GIRRRVDEIM NCEDIAMNFL ISHITGKPPI
KVTSRWNFNC PTCETTLTRD VNHFKKRNSC VNYFAQIYGY MPLIFSQFRV DSILYRTRVP
NGEQKCYESQ L
//
