ID A0A369WD83_9GAMM Unreviewed; 733 AA.
AC A0A369WD83;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
DE AltName: Full=DNA 3'-5' helicase II {ECO:0000256|ARBA:ARBA00034923};
GN ORFNames=DV711_16260 {ECO:0000313|EMBL:RDE19139.1};
OS Motiliproteus coralliicola.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Oceanospirillaceae; Motiliproteus.
OX NCBI_TaxID=2283196 {ECO:0000313|EMBL:RDE19139.1, ECO:0000313|Proteomes:UP000253769};
RN [1] {ECO:0000313|EMBL:RDE19139.1, ECO:0000313|Proteomes:UP000253769}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C34 {ECO:0000313|EMBL:RDE19139.1,
RC ECO:0000313|Proteomes:UP000253769};
RA Wang G.;
RT "Motiliproteus coralliicola sp. nov., a bacterium isolated from Coral.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Couples ATP hydrolysis with the unwinding of duplex DNA by
CC translocating in the 3'-5' direction.; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034617};
CC -!- SIMILARITY: Belongs to the helicase family. UvrD subfamily.
CC {ECO:0000256|ARBA:ARBA00009922}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDE19139.1}.
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DR EMBL; QQOH01000004; RDE19139.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A369WD83; -.
DR OrthoDB; 9806690at2; -.
DR Proteomes; UP000253769; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR CDD; cd17932; DEXQc_UvrD; 1.
DR CDD; cd18807; SF1_C_UvrD; 1.
DR Gene3D; 1.10.10.160; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR013986; DExx_box_DNA_helicase_dom_sf.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR PANTHER; PTHR11070:SF2; ATP-DEPENDENT DNA HELICASE SRS2; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF21196; PcrA_UvrD_tudor; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR Pfam; PF13361; UvrD_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
DR PROSITE; PS51217; UVRD_HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000253769}.
FT DOMAIN 8..286
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT DOMAIN 287..571
FT /note="UvrD-like helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51217"
FT BINDING 29..36
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 733 AA; 83320 MW; 2C932287258120B2 CRC64;
MDVSAILDPL NEAQREAVAA PPVNLLVLAG AGSGKTRVLV HRIAWLMQAE NVSPHGILAV
TFTNKAAREM RGRVEEMLGL SPYGMWIGTF HGLAHRLLRM HWQDAGLQEN FQILDSDDQL
RLVKRLMKEM NLDENRWQPK QLQWYINAQK DEGLRAAHIE HYGDPYQKVQ VDFYRYYEQV
CQQSSLVDFG EILLRSHELW RNKPEILAHY QQRFAHILVD EFQDTNSIQY AWLQMLAGQN
GKLMVVGDDD QSIYGWRGAK IENIQQFSQD HPDTLVVRLE QNYRSTGTIL RAANALIANN
QGRLGKELWT SGIDGEPISL YAGFNEQDEA RFIVDTVEDW VSEGNERASS AILYRSNAQS
RVLEEALIRA GVPYRIYGGQ RFYERLEIKN ALAYLRLVSN RLDDTAIERI INVPTRAIGP
KTVEVLRQRA RDEGISLWQA AHEVIELKLL PARASNALRA FVELIDRLDD ETEGVTLHEQ
TEHLIRHSGL IDHHLKEKGE KAQSRIENLQ ELVSAAKQFA QQWQRAEDQG EEQELPVLAA
FLDQAALDAG DAQADEFEDS VQLMTLHSAK GLEFPLVFLA GVEEGLFPHK MSMEEPGRLE
EERRLCYVGV TRAMSKLYLT YAESRRLHGQ DTYNRPSRFV QEIPAELMQE VRLKTQFTRP
VSFGAQKSQP SMFGGSDVPD TGLALGQRVM HPIFGEGVVL NYEGQGANAR VQVNFDSEGT
KWLVVSYAKL EPL
//
