ID   A0A370AQQ7_9SPIO        Unreviewed;       908 AA.
AC   A0A370AQQ7;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=RND family transporter {ECO:0000313|EMBL:RDG30469.1};
GN   ORFNames=DV872_16600 {ECO:0000313|EMBL:RDG30469.1};
OS   Oceanispirochaeta sp. M1.
OC   Bacteria; Spirochaetota; Spirochaetia; Spirochaetales; Spirochaetaceae;
OC   Oceanispirochaeta.
OX   NCBI_TaxID=2283433 {ECO:0000313|EMBL:RDG30469.1, ECO:0000313|Proteomes:UP000253869};
RN   [1] {ECO:0000313|EMBL:RDG30469.1, ECO:0000313|Proteomes:UP000253869}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=M1 {ECO:0000313|EMBL:RDG30469.1,
RC   ECO:0000313|Proteomes:UP000253869};
RA   Yadav S., Villanueva L., Damste J.S.S.;
RT   "Draft genome sequence of Oceanispirochaeta sp. strain M1.";
RL   Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RDG30469.1}.
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DR   EMBL; QQPQ01000024; RDG30469.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A370AQQ7; -.
DR   OrthoDB; 9809027at2; -.
DR   Proteomes; UP000253869; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR004869; MMPL_dom.
DR   InterPro; IPR000731; SSD.
DR   PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR   PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR   Pfam; PF03176; MMPL; 2.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   PROSITE; PS50156; SSD; 2.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000253869};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        213..232
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        239..259
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        265..286
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        315..338
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        344..369
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        407..424
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        735..753
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        760..780
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        786..807
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        835..856
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        862..886
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          242..369
FT                   /note="SSD"
FT                   /evidence="ECO:0000259|PROSITE:PS50156"
FT   DOMAIN          759..885
FT                   /note="SSD"
FT                   /evidence="ECO:0000259|PROSITE:PS50156"
SQ   SEQUENCE   908 AA;  100484 MW;  B61803BA3A7AF7FC CRC64;
     MKSMLKHPKI VIAVVMVITL VAGILSAGII LDNDVKVFFP KDDPSYLNVK ELDRTYGSQL
     MFDLCITTEK ETILTSDTIF LLQKMVAEIE TFDGVQSVTA ITNSDYPNGS ADGMSVSALV
     PDEFTGTDAE MSDLRERLLD WPEMYSRTLY SDDFKSTQII VRIDDELSAE EQSVLYYEVM
     EMIEPYDTYP LNFRIAGDPV ITQMGKEFMV RDLTMLIPFI SLVLFLCLLF AFKRITATLL
     PLITVMVATV WTVATMAYFD VDFTIVSSCL PVLIIAVGSA YGIHIINHYF HYKSTSKLLG
     PDAAIDNMRG SLKEVIAPIF LAGFTTVVGF ISIISSPIVP LKAFGAFAAI GTLYSLILSL
     TLIPALLVLS EKRRDKKNKS NEEFNDESED KGFIHWVISL TQEHGKATFA VVILLFGLST
     WGLFSINVES SLINYFPYNS DIRKDSRYIS DNFAGTNVFN IVINAPEGKS LADPEILKDM
     DELKIHLLNK YPEDIGKIIS FSDFIKRMNR IMNFPPEAAS EDDMFGTEDD LAMDSGDMGS
     FFDDSDDGMG SFFSDDESTD DGMDSFFDSE EETDNSYVES EYAYTDLSTN LNYTEFIMLL
     QSSMAEAGSL NVSVDTLVEK IMAQTNYRGA AYNEIPYDAS KYPVATKEEL GNLISQYLLL
     YSGSLDDYAT SPIDAPNEAR MMIQLKSHST SKTGEIIAEI NNYASHNIDP EWTITNAGVA
     ELELALTNMI TKSQITSLLI AIIAVFLIVA VSYRSITAGL IGIIPLAFSI LANFGLMSLM
     DINLDMVTAL IASIAIGIGV DYTVHFLSRY KLERAKSDDL NLVTRNTILS TGKGIIINAA
     SVGLGFSVLM FSKFIVLRYI GFLTAVIMVT SSMAALTILP LLLNVIKPKF VLSKESDTAL
     QPKKAVNK
//