ID A0A370AV54_9ACTN Unreviewed; 798 AA.
AC A0A370AV54;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=ATP-dependent helicase {ECO:0000313|EMBL:RDG33458.1};
GN ORFNames=DVH02_31280 {ECO:0000313|EMBL:RDG33458.1};
OS Streptomyces corynorhini.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=2282652 {ECO:0000313|EMBL:RDG33458.1, ECO:0000313|Proteomes:UP000253741};
RN [1] {ECO:0000313|EMBL:RDG33458.1, ECO:0000313|Proteomes:UP000253741}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AC230 {ECO:0000313|EMBL:RDG33458.1,
RC ECO:0000313|Proteomes:UP000253741};
RA Dunlap C.;
RT "Streptomyces species from bats.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDG33458.1}.
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DR EMBL; QQNA01000341; RDG33458.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A370AV54; -.
DR OrthoDB; 5318045at2; -.
DR Proteomes; UP000253741; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR InterPro; IPR027785; UvrD-like_helicase_C.
DR PANTHER; PTHR11070:SF2; ATP-DEPENDENT DNA HELICASE SRS2; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR Pfam; PF13538; UvrD_C_2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000253741}.
FT DOMAIN 5..265
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT BINDING 26..33
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 798 AA; 86918 MW; C6C7930033044F2F CRC64;
MAIEPTKEQQ AAREVFASGR DLALVAGAGT GKTSTLILMG AATRKRGLYV AFNRAIADDA
RGRFGPNVEC RTAHSLAFRA VGHHYRERLD ASARIPAKHT ARLLGITRDL DVNSRQIKVT
HAARLVMGMV RKFCYTTDRQ VMARHMEPVN GLDGPGQDYL ARTLLPYAHR AWQDICSPAG
RLRFEHDHYM KLWAMTSPRL GADFVLLDEA QDTNPVLEEV FLAQDAQRVC VGDPAQQIYG
WRNARDVMTG FPAEQLRLTQ SFRFGPAIAE VANRWLGHAE SEMQLTGHGP GSRVGEVAQP
EAVLCRGNVD AMSEVLSYLE LGVPVALTGG GSALQRIAKA ALELKAGQRT SHPELFLFSS
WGEVQEYAEQ DKAGQDLKAI VQLVDTYGPD QIIEAVDRLT PEESAKVIVS TAHKAKGREW
PSVRIGKGFM APSVDDHGLQ RALNASEARL IYVAVTRARH LLDTEGIAWI DAYEKTMADA
GRDGTVAGRP MIELSLTGQL KYDSSPISQF MAAHLPYSQN LVGDYQARIA GLAHPVQPID
VQYPNWSALG HAIDYRLRLS LGGRLGLAVV AGVMLLDETG PLRGAPARGT RKALHTAGRE
LLATVDTYLA APGSLDENAL IRLCFVAGFF EDIARTGEIR RFSMLGSATP ATTLADLTAA
VPEYVACDID QQTRLADAPF AAFRALPQKA RVCGPVFAGS GDIGGADADY ILDGLLLDCK
ATKDPRRLGR EEIYQLAGYL LLDYDDQFGI DSVGLYLSRQ GGLITWDAAG FLRRLGASAP
LTHLRAQLRR HLRKAALS
//
