ID A0A370B0Q7_9ACTN Unreviewed; 450 AA.
AC A0A370B0Q7;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE SubName: Full=Zinc carboxypeptidase {ECO:0000313|EMBL:RDG33949.1};
GN ORFNames=DVH02_30945 {ECO:0000313|EMBL:RDG33949.1};
OS Streptomyces corynorhini.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=2282652 {ECO:0000313|EMBL:RDG33949.1, ECO:0000313|Proteomes:UP000253741};
RN [1] {ECO:0000313|EMBL:RDG33949.1, ECO:0000313|Proteomes:UP000253741}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AC230 {ECO:0000313|EMBL:RDG33949.1,
RC ECO:0000313|Proteomes:UP000253741};
RA Dunlap C.;
RT "Streptomyces species from bats.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the peptidase M14 family.
CC {ECO:0000256|ARBA:ARBA00005988}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDG33949.1}.
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DR EMBL; QQNA01000328; RDG33949.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A370B0Q7; -.
DR OrthoDB; 5240362at2; -.
DR Proteomes; UP000253741; Unassembled WGS sequence.
DR GO; GO:0004181; F:metallocarboxypeptidase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR CDD; cd03859; M14_CPT; 1.
DR Gene3D; 3.40.630.10; Zn peptidases; 1.
DR InterPro; IPR033810; Carboxypeptidase_T.
DR InterPro; IPR000834; Peptidase_M14.
DR PANTHER; PTHR11705; PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B; 1.
DR PANTHER; PTHR11705:SF145; SLL0236 PROTEIN; 1.
DR Pfam; PF00246; Peptidase_M14; 1.
DR PRINTS; PR00765; CRBOXYPTASEA.
DR SMART; SM00631; Zn_pept; 1.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
DR PROSITE; PS00132; CARBOXYPEPT_ZN_1; 1.
DR PROSITE; PS00133; CARBOXYPEPT_ZN_2; 1.
PE 3: Inferred from homology;
KW Carboxypeptidase {ECO:0000313|EMBL:RDG33949.1};
KW Hydrolase {ECO:0000313|EMBL:RDG33949.1};
KW Protease {ECO:0000313|EMBL:RDG33949.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000253741};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..38
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 39..450
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5016868345"
FT DOMAIN 183..205
FT /note="Peptidase M14 carboxypeptidase A"
FT /evidence="ECO:0000259|PROSITE:PS00132"
FT DOMAIN 327..337
FT /note="Peptidase M14 carboxypeptidase A"
FT /evidence="ECO:0000259|PROSITE:PS00133"
SQ SEQUENCE 450 AA; 48554 MW; 222457D38A4EB3FB CRC64;
MRTRLRGIGG IGRRRPATLA AALLLTLGLA ATATTAAAGP PRPGATTAVG ERDTRQYEIQ
LHATSATRTA LARTGVSVDE SDSERVVVSA GPGQLAELRA LGYEPTALDA VPDRAGDGVV
TPYDFPPGDS AYHNYARMTA EINSVVAAHP TLASQRVIGT SYEGRNIVAI KISRNVAVDE
NEPEVLFTHH QHAREHLTVE MALYLLKELT SGYGTDARIT TLLDTREIWI IPDLNPDGGE
YDIATGSYRG WRKNRQPNSG STAVGTDLNR NWAYRWGCCG GSSGTTSSET YRGSAAESAP
EVKVVANFVR GRVVGGVQQI KAAIDFHTYS ELVMWPYGYT TATTAAGLTA DDRDAFATVG
RKMAASNGYT AQQSSALYIT DGSIDDWLWG THKIFAYTYE MYPRTSSSGG FYPPASVIGR
ETSRNRDAVL QLLENADCMY RSIGKQAQYC
//
