ID   A0A370BGZ4_9ACTN        Unreviewed;       825 AA.
AC   A0A370BGZ4;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=FAD-dependent oxidoreductase {ECO:0000313|EMBL:RDG39932.1};
GN   ORFNames=DVH02_01050 {ECO:0000313|EMBL:RDG39932.1};
OS   Streptomyces corynorhini.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=2282652 {ECO:0000313|EMBL:RDG39932.1, ECO:0000313|Proteomes:UP000253741};
RN   [1] {ECO:0000313|EMBL:RDG39932.1, ECO:0000313|Proteomes:UP000253741}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AC230 {ECO:0000313|EMBL:RDG39932.1,
RC   ECO:0000313|Proteomes:UP000253741};
RA   Dunlap C.;
RT   "Streptomyces species from bats.";
RL   Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the GcvT family.
CC       {ECO:0000256|ARBA:ARBA00008609}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RDG39932.1}.
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DR   EMBL; QQNA01000005; RDG39932.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A370BGZ4; -.
DR   OrthoDB; 2055370at2; -.
DR   Proteomes; UP000253741; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 2.40.30.110; Aminomethyltransferase beta-barrel domains; 1.
DR   Gene3D; 3.30.70.1400; Aminomethyltransferase beta-barrel domains; 1.
DR   Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR006076; FAD-dep_OxRdtase.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR032503; FAO_M.
DR   InterPro; IPR028896; GCST/YgfZ/DmdA.
DR   InterPro; IPR013977; GCV_T_C.
DR   InterPro; IPR006222; GCV_T_N.
DR   InterPro; IPR029043; GcvT/YgfZ_C.
DR   InterPro; IPR027266; TrmE/GcvT_dom1.
DR   PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR   PANTHER; PTHR43757:SF2; AMINOMETHYLTRANSFERASE, MITOCHONDRIAL; 1.
DR   Pfam; PF01266; DAO; 1.
DR   Pfam; PF16350; FAO_M; 1.
DR   Pfam; PF01571; GCV_T; 1.
DR   Pfam; PF08669; GCV_T_C; 1.
DR   SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR   SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   SUPFAM; SSF103025; Folate-binding domain; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000253741}.
FT   DOMAIN          17..382
FT                   /note="FAD dependent oxidoreductase"
FT                   /evidence="ECO:0000259|Pfam:PF01266"
FT   DOMAIN          385..439
FT                   /note="FAD dependent oxidoreductase central"
FT                   /evidence="ECO:0000259|Pfam:PF16350"
FT   DOMAIN          443..714
FT                   /note="Aminomethyltransferase folate-binding"
FT                   /evidence="ECO:0000259|Pfam:PF01571"
FT   DOMAIN          738..817
FT                   /note="Glycine cleavage T-protein C-terminal barrel"
FT                   /evidence="ECO:0000259|Pfam:PF08669"
SQ   SEQUENCE   825 AA;  89106 MW;  23B06B6B7E3A6A2B CRC64;
     MSSTSATATG SPGSAARVVV IGAGIVGCSL ADELTERGWS DVTVLDQGPL PAPGGSTSHA
     PGLLFSTNPS RTMTRFAAYT ARRLRRLDAE GVPCFDPVGG LEVATTPERW ADLHRKAGWA
     ASWGVAGELI TARRCAELWP LLDPDRLLGG FHTPDDGLVR AVPACRALAR RARERGARFL
     ERHTVTGVDR AGGRVTGVVT DRGTFPADVV ISAAGLWGPV IGKLAGVPVP LLPLAHQYAK
     SAPLPGLGGL AGESAPGGRP ILRFQDADLY FREHGDRIGI GSYDHRPLPV DPFTLPGYDA
     SPVMPSSLPF TPGDFGRAWQ ESGRLLPALA DSQVEEGFNG VFSFTADGMP LLGESPELRG
     FWLAEAVWIT HSAGVARAVA QWLTDGRPPV DVHACDVRRF EDVQLSPAYV AERGARQFDE
     VYDIVHPLQP AERARSLRVP PFHGRQRELG AVLLESAGWE RPQWYEANAP LAGSLELPPR
     DAWSARHWSP IVAAEARATR ERVALYDMTP LRRLEVTGPG ALAFLQRMTS NQLAKRPGSV
     TYTLLLDEAG GVRSDLTVAR LGERRFQVGA NSARDLDWLR RHAPADVRVR DITSGTCCVG
     VWGPLARDLV QPLTGDDFSH RGFGYFRCRE TYIGYVPVTA MRLSYVGELG WELYTSADLG
     LRLWDTLWEA GRPLGAVAAG RGAFDSLRLE KGYRAWGQDM TTEHNPYEAG LGFAVRPDKG
     EFTGRAALAG LSEETVTRRL TCLTLDDPAA VVLGNEPVYV DGAPVGYVTS AGYGYSIGRT
     VAYAWLPAAD SVPGTAVSVE YFGEKVPATV AREPLFDPEM ARIRR
//