ID A0A370DGG0_9GAMM Unreviewed; 419 AA.
AC A0A370DGG0;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN Name=phoR {ECO:0000313|EMBL:RDH83923.1};
GN ORFNames=DIZ80_07245 {ECO:0000313|EMBL:RDH83923.1};
OS endosymbiont of Galathealinum brachiosum.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; sulfur-oxidizing symbionts.
OX NCBI_TaxID=2200906 {ECO:0000313|EMBL:RDH83923.1, ECO:0000313|Proteomes:UP000254266};
RN [1] {ECO:0000313|EMBL:RDH83923.1, ECO:0000313|Proteomes:UP000254266}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A1464 {ECO:0000313|EMBL:RDH83923.1};
RX PubMed=30022157;
RA Li Y., Liles M.R., Halanych K.M.;
RT "Endosymbiont genomes yield clues of tubeworm success.";
RL ISME J. 0:0-0(2018).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDH83923.1}.
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DR EMBL; QFXC01000008; RDH83923.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A370DGG0; -.
DR Proteomes; UP000254266; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004721; F:phosphoprotein phosphatase activity; IEA:InterPro.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR021766; PhoR.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR014310; Sig_transdc_His_kinase_PhoR.
DR NCBIfam; TIGR02966; phoR_proteo; 1.
DR PANTHER; PTHR45453; PHOSPHATE REGULON SENSOR PROTEIN PHOR; 1.
DR PANTHER; PTHR45453:SF1; PHOSPHATE REGULON SENSOR PROTEIN PHOR; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF11808; PhoR; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:RDH83923.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000254266};
KW Transferase {ECO:0000313|EMBL:RDH83923.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..45
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 208..419
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 419 AA; 47832 MW; 0D4354D126B338AD CRC64;
MTFSSSLQHE LSLLTLWLIF MLVIGSFFGI AMTAVFVGLL GYVVWHLYNL NRLVNWLNKP
SNNTPEATGI WDDAFFQLHN QYKRQRGSRK RLTKILKQFQ KSTKALPYAT IVLNSNNEIE
WFNPASKILF GLRSGLDVGQ RIDNLIRQPE FIKYLNGNNF KKPLEFDNQN QKLLLNVTSY
GQGQYLLSAR DITQRIKLDE MRRDFISNAS HELRTPITVM SGYIETLQNN CDEINKYPVD
KIYQQTIRME KIIAELIELA KLETSSFIGT NVQIDTIALL NEVYNEAVSL DQGSHDITIE
IEPIKINGSY EEIRTAISNL LTNAVRYTPD NGFIKLTTST DSTGSYIHVE DNGDGIGYEH
ISRLTERFYR VDEGRSREKG GTGLGLAIVK QILDRHGAVL QIESEINKGT VFSCYFPFT
//
