ID   A0A370DTW8_9GAMM        Unreviewed;       474 AA.
AC   A0A370DTW8;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   RecName: Full=TIR domain-containing protein {ECO:0000259|Pfam:PF13676};
GN   ORFNames=DIZ78_05040 {ECO:0000313|EMBL:RDH87904.1};
OS   endosymbiont of Escarpia spicata.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; sulfur-oxidizing symbionts.
OX   NCBI_TaxID=2200908 {ECO:0000313|EMBL:RDH87904.1, ECO:0000313|Proteomes:UP000254771};
RN   [1] {ECO:0000313|EMBL:RDH87904.1, ECO:0000313|Proteomes:UP000254771}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=A1462 {ECO:0000313|EMBL:RDH87904.1};
RX   PubMed=30022157;
RA   Li Y., Liles M.R., Halanych K.M.;
RT   "Endosymbiont genomes yield clues of tubeworm success.";
RL   ISME J. 0:0-0(2018).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RDH87904.1}.
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DR   EMBL; QFXE01000005; RDH87904.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A370DTW8; -.
DR   Proteomes; UP000254771; Unassembled WGS sequence.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR   InterPro; IPR000157; TIR_dom.
DR   InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR   Pfam; PF13676; TIR_2; 1.
DR   SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000254771}.
FT   DOMAIN          9..106
FT                   /note="TIR"
FT                   /evidence="ECO:0000259|Pfam:PF13676"
SQ   SEQUENCE   474 AA;  53904 MW;  347479A5A347E099 CRC64;
     MARKKVSSVF ISYSHAAEEK VPIAAKLEAA FKKRGVGVLR RDTSETAYGE SIKRFMDELR
     KGDFVVVVSS ERYWHSDDCV NELKSIKEYG DFELRVLPVQ LQDINLRDVE IQKALINYWN
     SKSHDAASEI PKNAARAQAH AKEISDSAKC IDECISKFSD WYALDPATHI NSDFDALITT
     LLKRAELLQH KRAVLRFRRD VRDNFEKLLL AKPELGRRLE DEISPREGLH AAVDYLCGAA
     TAEHAEEAVF SLNNVGLAYL EQMSEIRDVN SSELKGVAEL LVSLLGWILL TQVNDQWISD
     NIDAFISGKS IEISLPLRTR TGVEILVARL NIKTPSLDFR KKEDHSISGN GVILESGYSS
     QCAAYEVKKS LWQMFWPTDE VPKVFEKGDR DKLNGQLRIE RRMATRRSIY IAIHQQDGTT
     CLTKDVVEQL QVELEELKFV YYGIEGGQGK ILLLPEYQVE NLVETFLKSL RKYL
//