ID A0A370H682_9NOCA Unreviewed; 1128 AA.
AC A0A370H682;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=DNA-binding SARP family transcriptional activator {ECO:0000313|EMBL:RDI49671.1};
GN ORFNames=DFR68_106106 {ECO:0000313|EMBL:RDI49671.1};
OS Nocardia mexicana.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=279262 {ECO:0000313|EMBL:RDI49671.1, ECO:0000313|Proteomes:UP000255355};
RN [1] {ECO:0000313|EMBL:RDI49671.1, ECO:0000313|Proteomes:UP000255355}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44952 {ECO:0000313|EMBL:RDI49671.1,
RC ECO:0000313|Proteomes:UP000255355};
RA Goeker M.;
RT "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT most valuable type-strain genomes for metagenomic binning, comparative
RT biology and taxonomic classification.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the AfsR/DnrI/RedD regulatory family.
CC {ECO:0000256|ARBA:ARBA00005820}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDI49671.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; QQAZ01000006; RDI49671.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A370H682; -.
DR STRING; 1210089.GCA_001613165_02272; -.
DR OrthoDB; 134712at2; -.
DR Proteomes; UP000255355; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd15831; BTAD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR005158; BTAD.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR35807:SF1; TRANSCRIPTIONAL REGULATOR REDD; 1.
DR PANTHER; PTHR35807; TRANSCRIPTIONAL REGULATOR REDD-RELATED; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF03704; BTAD; 1.
DR Pfam; PF00486; Trans_reg_C; 1.
DR SMART; SM01043; BTAD; 1.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS51755; OMPR_PHOB; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU01091}; Reference proteome {ECO:0000313|Proteomes:UP000255355}.
FT DOMAIN 1..101
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|PROSITE:PS51755"
FT DNA_BIND 1..101
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
FT REGION 1109..1128
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1128 AA; 120759 MW; 11E18F180B412B69 CRC64;
MMSDPQVQVF GPLQVLLGGR SARIGAGRQR AILGRLVLAG GKTLGVDRLV DDVWEGSPPP
HAPSVLQVQI HNLRRILEPG RRPRTPAQIL VSEGSGYALR LDSGNVDAWQ FEALLRQYED
RVHEPGDPPG PLERYRMLDA VLSCWHGAAF ESFAGASWAT AESARLTDLR ATAVEMRAQA
ALELDRVGEV VAVLRQQIEE YPGREETARL LALAQYRLGQ QVEALATVRR VRDYLRSEYG
IDPGPRLSEL EFALLNHTVV PDRAPGEPRR AAAVSAAPAR SAGVSEGADQ SGALPEASTC
YSVQRGAIAS ASIEARTAGT RLVWVVGDVG AGKTTLVRTA IADLAGAGWA TAYGKAPEVE
SAPAAWVWRE ILAEFGGESV LSEDLAEAVD PFTIVRAVAK RCRELAAAGG VAIVLDDMHR
SDTASLQVLR QLVSWLDREP VLIIVTARGP ELPPVLRATE AALADRVSER VELTGLDLPG
TREIAHGAGL VALDDDALQS LHRRTGGNPL FVRELSKLMV TQGESGSLPE SIRAVLSERT
ERLPEGVLAV LQHIAVWGRA IDLDTLIGLS GVGEGDIVDG IDAAAAAGLV GFDAAGRITL
DHALIRDTVY NSIPPLRQRR MHWNALEFLE RRSPEGPGDT ADLVCRARHA ARGAARSTAT
HALGYVVAAA LRCDGGGARA DAAEHWQAAV ALHELAGHAG DSADDGDRRA LVEALCALTG
SLAYGGRTLA ARAVRQRAVQ LASDIDDTAL RVRALTCWRA PVLTGIRDWR APDRSLTRLL
ESTLAQVDTP AERARVLVAL VLESEVVGAT EQVHRWAREA VDAAEATGDP ELLCAALNAL
AHVITGPAML DGWDRVADDL LRAARSARLP EYQAVAHYLR FRAACRVSDL RAASRHMTRA
LEYASAGQLR SLLDILPAFS AVSAVLCGDL EAAEAEYRRF DARMRQSGVA NEDETLLIGA
LTVAWARNDL SGPADRLAAL YEVEPELVAQ IYAMALIHAG DRDGARTVFR RHPAVRRDFY
WPVMAAFRAR AAVALGEVEV ARDLLEELRH CSGTLIGLAG GTAVFGPTDG VLADLADLVG
DPAAAEVFRA RAAALLRRAR ADLESLQPDV LHHGPGETER AAPELVCG
//
