ID A0A370HX17_9NOCA Unreviewed; 645 AA.
AC A0A370HX17;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Succinate dehydrogenase subunit A {ECO:0000313|EMBL:RDI63029.1};
GN ORFNames=DFR76_11145 {ECO:0000313|EMBL:RDI63029.1};
OS Nocardia pseudobrasiliensis.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=45979 {ECO:0000313|EMBL:RDI63029.1, ECO:0000313|Proteomes:UP000254869};
RN [1] {ECO:0000313|EMBL:RDI63029.1, ECO:0000313|Proteomes:UP000254869}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44290 {ECO:0000313|EMBL:RDI63029.1,
RC ECO:0000313|Proteomes:UP000254869};
RA Goeker M.;
RT "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT most valuable type-strain genomes for metagenomic binning, comparative
RT biology and taxonomic classification.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDI63029.1}.
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DR EMBL; QQBC01000011; RDI63029.1; -; Genomic_DNA.
DR RefSeq; WP_068002749.1; NZ_QQBC01000011.1.
DR AlphaFoldDB; A0A370HX17; -.
DR STRING; 1210086.GCA_001613105_05199; -.
DR Proteomes; UP000254869; Unassembled WGS sequence.
DR GO; GO:0033765; F:steroid dehydrogenase activity, acting on the CH-CH group of donors; IEA:UniProt.
DR GO; GO:0008152; P:metabolic process; IEA:UniProt.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 1.20.58.100; Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain; 1.
DR Gene3D; 3.90.700.10; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR InterPro; IPR003953; FAD-binding_2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR037099; Fum_R/Succ_DH_flav-like_C_sf.
DR InterPro; IPR015939; Fum_Rdtase/Succ_DH_flav-like_C.
DR InterPro; IPR030664; SdhA/FrdA/AprA.
DR InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR PANTHER; PTHR11632; SUCCINATE DEHYDROGENASE 2 FLAVOPROTEIN SUBUNIT; 1.
DR PANTHER; PTHR11632:SF89; SUCCINATE DEHYDROGENASE [IRON-SULFUR SUBUNIT] (SUCCINIC DEHYDROGENASE)-RELATED; 1.
DR Pfam; PF00890; FAD_binding_2; 1.
DR Pfam; PF02910; Succ_DH_flav_C; 1.
DR PIRSF; PIRSF000171; SDHA_APRA_LASPO; 1.
DR PRINTS; PR00368; FADPNR.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF46977; Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain; 1.
DR SUPFAM; SSF56425; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000254869}.
FT DOMAIN 10..430
FT /note="FAD-dependent oxidoreductase 2 FAD binding"
FT /evidence="ECO:0000259|Pfam:PF00890"
FT DOMAIN 489..587
FT /note="Fumarate reductase/succinate dehydrogenase
FT flavoprotein-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02910"
FT COILED 502..529
FT /evidence="ECO:0000256|SAM:Coils"
FT ACT_SITE 323
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000171-1"
SQ SEQUENCE 645 AA; 70506 MW; 02CBE2DA62F3120A CRC64;
MPEVERHKYD VVVIGAGGAG LRAVIEAREH GHSVAVVCKS LFGKAHTVMA EGGCAASMGN
ANEKDSWQTH FKDTMRGGKF LNNWRMAELH AQEAPDRVWE LETYGALFDR TADGRISQRN
FGGHTYPRLA HVGDRTGLEI IRTMQQKIVS LQQEDYAATG DYESRIKVFA ECTISDLLTD
DAGRIAGAFG YWRESGRFIL FETPAVVLAT GGIGKSYKVT SNSWEYTGDG HALALRAGAS
LINMEFLQFH PTGMVWPPSV KGILVTEGVR GDGGVLKNAD GKRFMFDYIP SVFKGQYAET
EEEADQWLRD NDSARRTPDL LPRDEVARAI NEEVKAGRGT PHGGVYLDIA SRLPAAEIMR
RLPSMHHQFK ELADVDITKE PMEVGPTCHY VMGGIEVDPD TGAATVPGLF AAGECSGGMH
GSNRLGGNSL SDLLVFGRRA GLGAASYVER LGDERPAIAE ADITAAAKTA LEPFDPPAEG
TGENPYTLHT DLQQTMNDLV GIIRKEHELK QAIERLAELR DRFDTVTVEG HRQFNPGWHL
ALDLRNMLLV SECVAQAALL RTESRGGHTR DDHPQMDPNW RNKLLVCRVD PDGVGQTVPA
VTVTPEDQTP MRSDLLALFE LGELEKYYTS AETAGHPSAA AKGDA
//
