ID A0A370I0L6_9NOCA Unreviewed; 1689 AA.
AC A0A370I0L6;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=ATP-dependent Lhr-like helicase {ECO:0000313|EMBL:RDI64295.1};
GN ORFNames=DFR76_108127 {ECO:0000313|EMBL:RDI64295.1};
OS Nocardia pseudobrasiliensis.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=45979 {ECO:0000313|EMBL:RDI64295.1, ECO:0000313|Proteomes:UP000254869};
RN [1] {ECO:0000313|EMBL:RDI64295.1, ECO:0000313|Proteomes:UP000254869}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44290 {ECO:0000313|EMBL:RDI64295.1,
RC ECO:0000313|Proteomes:UP000254869};
RA Goeker M.;
RT "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT most valuable type-strain genomes for metagenomic binning, comparative
RT biology and taxonomic classification.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDI64295.1}.
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DR EMBL; QQBC01000008; RDI64295.1; -; Genomic_DNA.
DR STRING; 1210086.GCA_001613105_02700; -.
DR Proteomes; UP000254869; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd17922; DEXHc_LHR-like; 1.
DR CDD; cd18796; SF2_C_LHR; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013701; DEAD/DEAH_assoc.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR47962:SF5; ATP-DEPENDENT HELICASE LHR-RELATED; 1.
DR PANTHER; PTHR47962; ATP-DEPENDENT HELICASE LHR-RELATED-RELATED; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF08494; DEAD_assoc; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000313|EMBL:RDI64295.1};
KW Hydrolase {ECO:0000313|EMBL:RDI64295.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000254869}.
FT DOMAIN 27..219
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 259..439
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 626..673
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1253..1381
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1436..1469
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1253..1272
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1689 AA; 181046 MW; 6D1F2B66A1501F5F CRC64;
MDRFSRPTRE WFDGAFDAPT AAQLGAWQAI SAGEHTLVVA PTGSGKTLSA FLWAIDRLAT
REPTDGPRRT SVLYISPLKA LAVDVERNLR APLVGITQTA KRLGLAAPEV TVGVRSGDTS
ATARRSMQRT PPDILITTPE SLFLMLTSAA RETLSEVRTV IVDEVHAIAG SKRGAHLALS
LARLDLLTER PAQRIGLSAT VRPPEEVGRF LVGAAPISIV SPPAPKTFDL SVRVPVADMT
EPGDSDDQPG SIWPHVDSAI VDLVLAHHSS IVFANSRRLA ERLTARLNEA YTARLGDPVE
TEHGPPAQLG PSTEVTHGAE QLLARAHHGS VSKEQRALIE DDLKSGRLRC VVATSSLELG
IDMGAVDLVV QVEAPPSVAS GLQRVGRAGH QVGEVSRGVI FPKHRTDVVH CAVASMRMTA
GQIEQLSVPA HPLDILAQQT VAACALEPID VDTWFETVRG TGSYATLPRS AYESVLDLLA
GRYPSDEFAE LRPRVVWDRD AGTLTGRPGA QRLAVTSGGA IPDRGLFPVF MVGEKASRVG
ELDEEMVYES RVGDVFALGA TSWRIEEITH DRVLVSPAFG LPGRLPFWHG DSLGRPAELG
AALGEFIRTA GQAVERAPSA RVDALAHTAA APPSPRSTDG SDVAGSATGS GKRARSAPPT
GETRGRSGAG KRGAELDELE RLVHAAGLDD FATANLVALL RDQQQATGHL PTDRTLVVER
FRDELGDWRL VLHSPYGLPV HAPWALAIGA RLREQFGVDA APTASDDGIV VRLPDTTDDP
PGAELFVFDS DEIDDLVTEQ VGASALFASR FRECAARALL LPRRDPGRRA PLWQQRQRAA
QLLDVARKFP DFPILLETVR ECLQDVYDLP ALRRLLGEVA RRKLRLVAVE TATPSPFANA
LLFDYIGQFM YEGDSPLAER RAAALSLDSS LLAELLGRVE LRELLDAAVL EQTERELQRL
TPERHARDLE GLADLLRLLG PLTPAEAALR CTDDPGPWFE QLSKTRRALE VSFAGARWWV
AVEDAARLRD ALGVPLPIGT PTAFIEPVAD PLGDLIGRYA RTHGPFTLEA VARRLGIGTA
VAATALHRLA AEKRVVEGEF TPGSAGAEWC DSQILRRLRR RSLAAARKEV EPVPTAAFAR
FLPAWQHVDT GDLRGVDGVA AVVEQLAGVP IPASAWESLI LPARVRDYSP AMLDELMATG
EVVWSGHGSI TAKDGWIALH PADQLPLTLP PPDDIDLTET QSQLLLSLGA TLIPTSTGSP
RAARQTSASA DTPGHRAALD RAATPAARQR PPRISPPDIT AADSIDTRAV GPQDTSHPPG
PSSDPSGQPA TNSGLLGPHG GSRAADPPFD DSAGPDRSSS APSGERIPPR TDSDSTEGRV
KVVPSTGGAY FFRQLSDATG LLDDTAVASA LWELVWAGHV SGDTFAPVRA MLSGTTRTTT
AHRTPRRTPR GRMYLPRANM PTRSGPPTVA GRWSLLPERV DDNTVRAHAT ADVLLERYGV
LTRGSVQSEG VPGGFALMYR VLTEFEDRGR CRRGYFVDSL GGAQFSTTDV VDRLRSYDTE
RSEKSPPKAL TLAACDPANP YGAALPWPKA AAEGHRPGRK AGALVVLVNG ELTLYLERGG
KTLLTFTENP EARTQAAAAL AALVHTRRVD SLVIDRVDGE SVHGNTFATF LTEAGFAATP
RGFRLRSKP
//
