ID   A0A370IBZ9_9NOCA        Unreviewed;      1314 AA.
AC   A0A370IBZ9;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=Trehalose 6-phosphatase {ECO:0000313|EMBL:RDI68259.1};
GN   ORFNames=DFR76_102660 {ECO:0000313|EMBL:RDI68259.1};
OS   Nocardia pseudobrasiliensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC   Nocardia.
OX   NCBI_TaxID=45979 {ECO:0000313|EMBL:RDI68259.1, ECO:0000313|Proteomes:UP000254869};
RN   [1] {ECO:0000313|EMBL:RDI68259.1, ECO:0000313|Proteomes:UP000254869}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44290 {ECO:0000313|EMBL:RDI68259.1,
RC   ECO:0000313|Proteomes:UP000254869};
RA   Goeker M.;
RT   "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT   most valuable type-strain genomes for metagenomic binning, comparative
RT   biology and taxonomic classification.";
RL   Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RDI68259.1}.
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DR   EMBL; QQBC01000002; RDI68259.1; -; Genomic_DNA.
DR   STRING; 1210086.GCA_001613105_01236; -.
DR   Proteomes; UP000254869; Unassembled WGS sequence.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IEA:UniProtKB-KW.
DR   GO; GO:0005992; P:trehalose biosynthetic process; IEA:InterPro.
DR   CDD; cd01627; HAD_TPP; 1.
DR   Gene3D; 1.50.10.10; -; 1.
DR   Gene3D; 2.70.98.40; Glycoside hydrolase, family 65, N-terminal domain; 1.
DR   Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 2.
DR   Gene3D; 2.60.420.10; Maltose phosphorylase, domain 3; 1.
DR   InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR   InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR   InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR   InterPro; IPR005194; Glyco_hydro_65_C.
DR   InterPro; IPR005195; Glyco_hydro_65_M.
DR   InterPro; IPR005196; Glyco_hydro_65_N.
DR   InterPro; IPR037018; Glyco_hydro_65_N_sf.
DR   InterPro; IPR036412; HAD-like_sf.
DR   InterPro; IPR006439; HAD-SF_hydro_IA.
DR   InterPro; IPR023214; HAD_sf.
DR   InterPro; IPR023198; PGP-like_dom2.
DR   InterPro; IPR003337; Trehalose_PPase.
DR   NCBIfam; TIGR01509; HAD-SF-IA-v3; 1.
DR   NCBIfam; TIGR00685; T6PP; 1.
DR   PANTHER; PTHR11051; GLYCOSYL HYDROLASE-RELATED; 1.
DR   PANTHER; PTHR11051:SF8; PROTEIN-GLUCOSYLGALACTOSYLHYDROXYLYSINE GLUCOSIDASE; 1.
DR   Pfam; PF03633; Glyco_hydro_65C; 1.
DR   Pfam; PF03632; Glyco_hydro_65m; 1.
DR   Pfam; PF03636; Glyco_hydro_65N; 1.
DR   Pfam; PF00702; Hydrolase; 1.
DR   Pfam; PF02358; Trehalose_PPase; 1.
DR   SFLD; SFLDG01129; C1.5:_HAD__Beta-PGM__Phosphata; 1.
DR   SFLD; SFLDS00003; Haloacid_Dehalogenase; 1.
DR   SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR   SUPFAM; SSF56784; HAD-like; 2.
DR   SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
PE   4: Predicted;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00023295};
KW   Reference proteome {ECO:0000313|Proteomes:UP000254869}.
FT   DOMAIN          525..781
FT                   /note="Glycoside hydrolase family 65 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF03636"
FT   DOMAIN          835..1230
FT                   /note="Glycoside hydrolase family 65 central catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF03632"
FT   DOMAIN          1240..1303
FT                   /note="Glycoside hydrolase family 65 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF03633"
SQ   SEQUENCE   1314 AA;  144242 MW;  5C6CF4D470ADC03D CRC64;
     MVQGDETGVC LDPRRYDAVI FDMDGVVTDS ARIHEAAWKQ MFDEFLGDAP PFTETDYERF
     VDGKPRTGGV ADFLASRDIS LPWGAPSDPP EAVTVCGLGN RKDRLFLERI GRDGVPAFAS
     TVALVRQLRA AGVGTAIFSA SRNCAQVLAA AGIGDLFTVR VDGLVAESLG LAGKPDPAML
     LEAARRLGAD AERTVVVEDA EAGVAAGRRG GFGLVIGVDR VGHADRLAAG GADVVVTDLA
     EVGLRDGFRR MSELPDVFTY WPRVVDVLDG EKVAVLADFD GTLAEIVTDP NAARPVEHVG
     DTLGRLARLC PVAVISGRNL DDLRERVGAR GIWYAGSHGF ELLAPDGTHH VHEAGIAAEP
     VIAEAAAELT ARLREIVGVV VEHKRFTVAV HHRNVAAGQV GAVVAAVHEV GRQTGLRVTG
     GRKVTELRPD LDWDKGHALR WILERLDGPA LPIYLGDDLT DEDAFDAMGA EGVSIVVRHS
     ENGDRRSAAH FAVDGPARVR EFLDRVGELL SGASTASASE SWLLTYDGYD PAAEKLREAL
     CTVGNGYLAT RGAAPEARAG ERHYPGTYLA GVFNRLSDEV SGRTVENESM VNAPNWLPVS
     WRIDGSDWFC VDEAEMLSYR KEFDLRRAVL TRRLRYRDDE GRITVVCQRR FAAMHAPHVC
     ALETTVTPEN WAGLLTVRTM IDTGVRNSLV ERYRELSDRH LTTLSTARPS PGTVLALVRT
     SRSHILIATA TRTVIRHNDE YVDATTRLVD ESDGIGDEFD IAVRPGDTVV LEKVATVFTG
     RDRAVSAPEV QAVREFGDLG DFDALLRAHS NAWEHLWARL RIHFDGTAEA ARTVRLHMLH
     LVQTLSPHTV DLDAGVPARG LHGEAYRGHV FWDELFVLPV LNLRIPTISR SLLEYRHRRL
     PEARRLAREI GCAGALFPWQ SGSDGREESQ QLHLNPRSGH WRADASRRAH HAGIAVAYTV
     WQYYQVTGDV DFLAGTGAEL LVEIARFWAS SAVYDAADDR YHLRGVIGPD EFHSGYPDRP
     DDGIDDNAYT NVMAAWVIRR AREALDSVAP RVRGELMETL GVAPGESAHW AEVADRLAVP
     FHDGVISQFA GYRELAELDW DDYTGRYGDI ARLDRILEAE GDDVNRYRVA KQADVLMLFY
     LLSADELREL LGRMGYDLPG EMIPRTIDYY LARTTHGSTL SAVVHSWVLA RANRHRALEF
     FGTVLESDIA DIQGGTTAEG IHLAAMAGSV DLLQRCFTGL EIRASRLIFN PRWPRALSAL
     SFPMVYRGHR LTVRIDADYL EIGSDPVVAP HIEIDCRGRR VRLAPGESIR IPVG
//