ID A0A370NB52_9BURK Unreviewed; 329 AA.
AC A0A370NB52;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Glycerate dehydrogenase {ECO:0000313|EMBL:RDK02840.1};
GN ORFNames=DLM46_11405 {ECO:0000313|EMBL:RDK02840.1};
OS Paraburkholderia lacunae.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Paraburkholderia.
OX NCBI_TaxID=2211104 {ECO:0000313|EMBL:RDK02840.1, ECO:0000313|Proteomes:UP000254875};
RN [1] {ECO:0000313|Proteomes:UP000254875}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S27 {ECO:0000313|Proteomes:UP000254875};
RA Feng T.;
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the D-isomer specific 2-hydroxyacid
CC dehydrogenase family. {ECO:0000256|RuleBase:RU003719}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDK02840.1}.
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DR EMBL; QHKS01000006; RDK02840.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A370NB52; -.
DR OrthoDB; 9805416at2; -.
DR Proteomes; UP000254875; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd12162; 2-Hacid_dh_4; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR006139; D-isomer_2_OHA_DH_cat_dom.
DR InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43761:SF1; 2-HACID_DH DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR43761; D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_1G13630); 1.
DR Pfam; PF00389; 2-Hacid_dh; 1.
DR Pfam; PF02826; 2-Hacid_dh_C; 1.
DR SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|RuleBase:RU003719};
KW Reference proteome {ECO:0000313|Proteomes:UP000254875}.
FT DOMAIN 32..326
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase
FT catalytic"
FT /evidence="ECO:0000259|Pfam:PF00389"
FT DOMAIN 113..296
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02826"
SQ SEQUENCE 329 AA; 36047 MW; 8822CC1CC48DF6B9 CRC64;
MHGTARPLRV VFLDRATISP QTKLKELPFP HVFELFDHTA AEQVSSRIRY ADIVLTNKVR
LTARDIADAS NLKMIAVAAT GTDHIDLQAC VARGVVVSNI RNYAVQTVPE HTFALIFALR
RSLTAYRDAV RAGRWFESGQ FCFFDYPIRD LKGSTLGVIG DGVLGRAVAE IGRALGMRVL
FSAYKDRTDM GPLYTPFDEL LQQSDVITLH CPLTAATRNL IAEPEFARIA KGRRRPLIVN
TARGGLVDEA ALVAALKAGT ISGAGFDVVT QEPLPEDHLF NEVLGHPAFI LTPHVAWASD
EAIQCLADQL VENIVTFVEG RPAHVVTPQ
//
