ID A0A370NCV8_9BURK Unreviewed; 100 AA.
AC A0A370NCV8;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=Periplasmic mercury ion-binding protein {ECO:0000256|RuleBase:RU361212};
GN Name=merP {ECO:0000256|RuleBase:RU361212,
GN ECO:0000313|EMBL:RDK03436.1};
GN ORFNames=DLM46_07890 {ECO:0000313|EMBL:RDK03436.1};
OS Paraburkholderia lacunae.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Paraburkholderia.
OX NCBI_TaxID=2211104 {ECO:0000313|EMBL:RDK03436.1, ECO:0000313|Proteomes:UP000254875};
RN [1] {ECO:0000313|Proteomes:UP000254875}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S27 {ECO:0000313|Proteomes:UP000254875};
RA Feng T.;
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in mercury resistance. Acts as a mercury scavenger
CC that specifically binds to a mercuric ion in the periplasm and probably
CC passes it to the cytoplasmic mercuric reductase MerA via the mercuric
CC transport protein MerT. {ECO:0000256|RuleBase:RU361212}.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000256|RuleBase:RU361212}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDK03436.1}.
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DR EMBL; QHKS01000004; RDK03436.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A370NCV8; -.
DR OrthoDB; 7205933at2; -.
DR Proteomes; UP000254875; Unassembled WGS sequence.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR GO; GO:0045340; F:mercury ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0015097; F:mercury ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR CDD; cd00371; HMA; 1.
DR Gene3D; 3.30.70.100; -; 1.
DR InterPro; IPR006121; HMA_dom.
DR InterPro; IPR036163; HMA_dom_sf.
DR InterPro; IPR011795; MerP.
DR InterPro; IPR001802; MerP/CopZ.
DR NCBIfam; TIGR02052; MerP; 1.
DR Pfam; PF00403; HMA; 1.
DR PRINTS; PR00946; HGSCAVENGER.
DR SUPFAM; SSF55008; HMA, heavy metal-associated domain; 1.
DR PROSITE; PS50846; HMA_2; 1.
PE 4: Predicted;
KW Mercuric resistance {ECO:0000256|RuleBase:RU361212};
KW Mercury {ECO:0000256|RuleBase:RU361212};
KW Metal-binding {ECO:0000256|RuleBase:RU361212};
KW Periplasm {ECO:0000256|RuleBase:RU361212};
KW Reference proteome {ECO:0000313|Proteomes:UP000254875};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..100
FT /note="Periplasmic mercury ion-binding protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5016785888"
FT DOMAIN 31..97
FT /note="HMA"
FT /evidence="ECO:0000259|PROSITE:PS50846"
SQ SEQUENCE 100 AA; 10332 MW; 68345D387FED00F3 CRC64;
MRKLPIAAIA AIAALAALAA LPLLTLAAAP RTVTLDVKNM TCELCPVTVR KSLEKVPGVS
AVKVDFDGKT ATVTYDPAKA QPDALTRATA NAGYPSTLQK
//
