ID   A0A370Q9Y1_9FLAO        Unreviewed;       719 AA.
AC   A0A370Q9Y1;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=DNA mismatch repair protein MutS2 {ECO:0000313|EMBL:RDK85188.1};
GN   ORFNames=C8D94_1036 {ECO:0000313|EMBL:RDK85188.1};
OS   Marinirhabdus gelatinilytica.
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae.
OX   NCBI_TaxID=1703343 {ECO:0000313|EMBL:RDK85188.1, ECO:0000313|Proteomes:UP000255317};
RN   [1] {ECO:0000313|EMBL:RDK85188.1, ECO:0000313|Proteomes:UP000255317}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 101478 {ECO:0000313|EMBL:RDK85188.1,
RC   ECO:0000313|Proteomes:UP000255317};
RA   Goeker M.;
RT   "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT   most valuable type-strain genomes for metagenomic binning, comparative
RT   biology and taxonomic classification.";
RL   Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RDK85188.1}.
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DR   EMBL; QRAO01000003; RDK85188.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A370Q9Y1; -.
DR   OrthoDB; 9808166at2; -.
DR   Proteomes; UP000255317; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0004519; F:endonuclease activity; IEA:InterPro.
DR   GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR   GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR   GO; GO:0045910; P:negative regulation of DNA recombination; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR   InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR   InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR   InterPro; IPR005747; MutS2.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR48378:SF1; DNA MISMATCH REPAIR PROTEINS MUTS FAMILY DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR48378; DNA MISMATCH REPAIR PROTEINS MUTS FAMILY DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR   Pfam; PF00488; MutS_V; 1.
DR   PIRSF; PIRSF005814; MutS_YshD; 1.
DR   SMART; SM00534; MUTSac; 1.
DR   SMART; SM00533; MUTSd; 1.
DR   SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000255317}.
FT   DOMAIN          12..316
FT                   /note="DNA mismatch repair protein MutS core"
FT                   /evidence="ECO:0000259|SMART:SM00533"
FT   DOMAIN          335..520
FT                   /note="DNA mismatch repair proteins mutS family"
FT                   /evidence="ECO:0000259|SMART:SM00534"
FT   REGION          654..674
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          530..585
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        654..669
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   719 AA;  82457 MW;  70C5C634DD695C96 CRC64;
     MVKIDKKTLE DVEFPKVLEQ VSEFCITAPG NKMVLEITPF KNTEKVLPSL KRVKEFTASF
     GSDSPIPNHG FEPIYKELQL LEIENSTLES FSFRKLLSLS ETTQSLLKFF KKFEEFYISL
     QEFSEQIEFA PSIAEEIKKI FDKYGNVKDE ASTELGTIRR RLNVVKGQIN SSFSKALSKY
     AGSDYLDDIR ETVVDNRRVL AVTAMYRRKI KGTVLGQSKT GSIVYMEPQE TLEYANELSN
     LEYEEREEVK RILKVLTEFV RPYNHHLASY QEYLTVIDAM YAKAKYAVEI NGVLPLLTKE
     RQLHLLDAYH PLLLVSNRKR KEKTYPQTIQ LSQDKRIIVI SGPNAGGKSI TLKTVGLLQV
     MLQSGLLIPV EPQSEVCFFD KLLTDIGDNQ SIENHLSTYS YRLKKMKHFL RKCNENTLFL
     IDEFGTGSDP ELGGALAETF LEVFYEREAF GIITTHYANL KLLANELPHA VNANMQFDSK
     SLAPVYKLQM GEAGSSFTFE VAQKNGIPYS LINRSKKKIE RGKIRFDKTI ANLQKERSKL
     RKTSETLETS AEKARKESEQ LAEVNAKVQE KLESYQELYD ANQKLLTLGR RFDSLAEKFF
     NNKQKKQLMD ELYKLVMTEN SKRKKLAPKQ KKAVKRKKHE LKQEVEQKVA KIRKEKKKEK
     AKAKKAPPPK PKVTLKVGDR VRMIDGRAIG TIDAIEKNKA FVNYGMFTTN VSLEELEKV
//