ID   A0A370WYD2_9GAMM        Unreviewed;       351 AA.
AC   A0A370WYD2;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   24-JAN-2024, entry version 14.
DE   RecName: Full=DNA topoisomerase {ECO:0000256|ARBA:ARBA00012891};
DE            EC=5.6.2.1 {ECO:0000256|ARBA:ARBA00012891};
GN   ORFNames=DWU98_11405 {ECO:0000313|EMBL:RDS81142.1};
OS   Dyella monticola.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC   Rhodanobacteraceae; Dyella.
OX   NCBI_TaxID=1927958 {ECO:0000313|EMBL:RDS81142.1, ECO:0000313|Proteomes:UP000254258};
RN   [1] {ECO:0000313|EMBL:RDS81142.1, ECO:0000313|Proteomes:UP000254258}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=4G-K06 {ECO:0000313|EMBL:RDS81142.1,
RC   ECO:0000313|Proteomes:UP000254258};
RA   Gao Z., Qiu L.;
RT   "Dyella monticola sp. nov. and Dyella psychrodurans sp. nov. isolated from
RT   monsoon evergreen broad-leaved forest soil of Dinghu Mountain, China.";
RL   Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP-independent breakage of single-stranded DNA, followed by
CC         passage and rejoining.; EC=5.6.2.1;
CC         Evidence={ECO:0000256|ARBA:ARBA00000213};
CC   -!- SIMILARITY: Belongs to the type IB topoisomerase family.
CC       {ECO:0000256|ARBA:ARBA00006645}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RDS81142.1}.
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DR   EMBL; QRBE01000006; RDS81142.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A370WYD2; -.
DR   OrthoDB; 9778962at2; -.
DR   Proteomes; UP000254258; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003917; F:DNA topoisomerase type I (single strand cut, ATP-independent) activity; IEA:InterPro.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   Gene3D; 1.10.132.120; -; 1.
DR   Gene3D; 3.30.66.10; DNA topoisomerase I domain; 1.
DR   InterPro; IPR011010; DNA_brk_join_enz.
DR   InterPro; IPR035447; DNA_topo_I_N_sf.
DR   InterPro; IPR049331; Top1B_N_bact.
DR   InterPro; IPR001631; TopoI.
DR   InterPro; IPR014711; TopoI_cat_a-hlx-sub_euk.
DR   InterPro; IPR013500; TopoI_cat_euk.
DR   Pfam; PF21338; Top1B_N_bact; 1.
DR   Pfam; PF01028; Topoisom_I; 1.
DR   PRINTS; PR00416; EUTPISMRASEI.
DR   SUPFAM; SSF56349; DNA breaking-rejoining enzymes; 1.
DR   SUPFAM; SSF55869; DNA topoisomerase I domain; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:RDS81142.1};
KW   Topoisomerase {ECO:0000256|ARBA:ARBA00023029}.
FT   DOMAIN          36..84
FT                   /note="DNA topoisomerase IB N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF21338"
FT   DOMAIN          97..305
FT                   /note="DNA topoisomerase I catalytic core eukaryotic-type"
FT                   /evidence="ECO:0000259|Pfam:PF01028"
SQ   SEQUENCE   351 AA;  40043 MW;  58B469248E9D5287 CRC64;
     MDVSTSTVLK RRIRAQGLVY VSDREPGIRR LRCGQGFVYR HRTGRPVVDR RILNRIRRLA
     IPPAYKDVWI CVDPHGHLQA TGRDDRGRKQ YRYHPDWRTF RDAGKFANLV AFGRALPAIR
     RKVRHDLALP GLSHDKVIAT VVALLDKTLI RVGNESYVQE NGSYGLTTLR SRHLKHERGR
     LRFVFKGKSG VERDVELDDK RLIKIIRSIH KLPGQKLFQY LDDDGVRQPV DSSAVNHYLR
     EAAGSTDEEC FSAKNFRTWG ATLLAAKLLG KRPLPEKGGL RARKHVVTRA VKEVATTMGN
     TPAVCRSSYI DPCVIEDWLD DGLSGQAFTT LRGRRLEKAL VRYLEKRHRT G
//