ID A0A371BE92_9SPHN Unreviewed; 388 AA.
AC A0A371BE92;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=M48 family peptidase {ECO:0000313|EMBL:RDV05929.1};
GN ORFNames=DXH95_00250 {ECO:0000313|EMBL:RDV05929.1};
OS Sphingorhabdus pulchriflava.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingorhabdus.
OX NCBI_TaxID=2292257 {ECO:0000313|EMBL:RDV05929.1, ECO:0000313|Proteomes:UP000263833};
RN [1] {ECO:0000313|Proteomes:UP000263833}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GY_G {ECO:0000313|Proteomes:UP000263833};
RA Kim S.-J., Jung G.-Y.;
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|RuleBase:RU003983};
CC Note=Binds 1 zinc ion per subunit. {ECO:0000256|RuleBase:RU003983};
CC -!- SIMILARITY: Belongs to the peptidase M48 family.
CC {ECO:0000256|RuleBase:RU003983}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDV05929.1}.
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DR EMBL; QRGP01000001; RDV05929.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A371BE92; -.
DR OrthoDB; 9781930at2; -.
DR Proteomes; UP000263833; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.30.2010.10; Metalloproteases ('zincins'), catalytic domain; 1.
DR InterPro; IPR001915; Peptidase_M48.
DR InterPro; IPR032456; Peptidase_M48_N.
DR PANTHER; PTHR10120; CAAX PRENYL PROTEASE 1; 1.
DR PANTHER; PTHR10120:SF24; CAAX PRENYL PROTEASE 1 HOMOLOG; 1.
DR Pfam; PF01435; Peptidase_M48; 1.
DR Pfam; PF16491; Peptidase_M48_N; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU003983};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049,
KW ECO:0000256|RuleBase:RU003983};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|RuleBase:RU003983};
KW Reference proteome {ECO:0000313|Proteomes:UP000263833};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU003983}.
FT TRANSMEM 31..50
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 71..91
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 111..137
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 144..167
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 256..278
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 14..172
FT /note="CAAX prenyl protease 1 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16491"
FT DOMAIN 182..378
FT /note="Peptidase M48"
FT /evidence="ECO:0000259|Pfam:PF01435"
SQ SEQUENCE 388 AA; 43174 MW; F2D42E075665C340 CRC64;
MTFNPAAETA RYIDSLGPEA LQKAANYTSG GHWMLLWGLA VSAVVTLIMV RSRILDRVAV
RFEKRGRAFR TWLIAMVYFL SSALLTLPWT LYEDYFREKS YGRTSQPLAD FLVQDAMGTM
LFSIFGGLFF LGVYALIRRT GKKWWLWSGG LGAAAITVTI LLSPLLIEPL FNNYKPVPEG
PVRTALVEMG AEAGIAEDRI VMFDGSRQSN NFTANVSGVF GTGRIAISDV ALKQASLDEV
KAVTGHEIGH YVLGHVWRFV FLFSGMAIVG FFLTNLMYDR VASMFGSKAQ IGDPEGLPII
MFTMSLLFLF AQPLNGVIRM GESEADDYSL RTVNLPDALA GALIKTAEYR YPRPSAIEEA
IFYSHPSIER RIRNAMEWKA KGLEKAVR
//
