ID A0A371DD49_9APHY Unreviewed; 523 AA.
AC A0A371DD49;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=Importin subunit alpha {ECO:0000256|PIRNR:PIRNR005673};
GN ORFNames=OH76DRAFT_1402479 {ECO:0000313|EMBL:RDX50443.1};
OS Polyporus brumalis.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Polyporales; Polyporaceae; Polyporus.
OX NCBI_TaxID=139420 {ECO:0000313|EMBL:RDX50443.1, ECO:0000313|Proteomes:UP000256964};
RN [1] {ECO:0000313|EMBL:RDX50443.1, ECO:0000313|Proteomes:UP000256964}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BRFM 1820 {ECO:0000313|EMBL:RDX50443.1,
RC ECO:0000313|Proteomes:UP000256964};
RX PubMed=30061923; DOI=10.1186/s13068-018-1198-5;
RA Miyauchi S., Rancon A., Drula E., Hage H., Chaduli D., Favel A., Grisel S.,
RA Henrissat B., Herpoel-Gimbert I., Ruiz-Duenas F.J., Chevret D., Hainaut M.,
RA Lin J., Wang M., Pangilinan J., Lipzen A., Lesage-Meessen L., Navarro D.,
RA Riley R., Grigoriev I.V., Zhou S., Raouche S., Rosso M.N.;
RT "Integrative visual omics of the white-rot fungus Polyporus brumalis
RT exposes the biotechnological potential of its oxidative enzymes for
RT delignifying raw plant biomass.";
RL Biotechnol. Biofuels 11:201-201(2018).
CC -!- SIMILARITY: Belongs to the importin alpha family.
CC {ECO:0000256|ARBA:ARBA00010394, ECO:0000256|PIRNR:PIRNR005673}.
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DR EMBL; KZ857399; RDX50443.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A371DD49; -.
DR STRING; 139420.A0A371DD49; -.
DR Proteomes; UP000256964; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0061608; F:nuclear import signal receptor activity; IEA:InterPro.
DR GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR Gene3D; 1.20.5.690; Importin-alpha, importin-beta-binding domain; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR032413; Arm_3.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR002652; Importin-a_IBB.
DR InterPro; IPR036975; Importin-a_IBB_sf.
DR InterPro; IPR024931; Importin_alpha.
DR PANTHER; PTHR23316; IMPORTIN ALPHA; 1.
DR PANTHER; PTHR23316:SF71; IMPORTIN SUBUNIT ALPHA; 1.
DR Pfam; PF00514; Arm; 8.
DR Pfam; PF16186; Arm_3; 1.
DR Pfam; PF01749; IBB; 1.
DR PIRSF; PIRSF005673; Importin_alpha; 1.
DR SMART; SM00185; ARM; 8.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50176; ARM_REPEAT; 4.
DR PROSITE; PS51214; IBB; 1.
PE 3: Inferred from homology;
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|PIRNR:PIRNR005673};
KW Reference proteome {ECO:0000313|Proteomes:UP000256964};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR005673}.
FT DOMAIN 1..55
FT /note="IBB"
FT /evidence="ECO:0000259|PROSITE:PS51214"
FT REPEAT 109..147
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 151..193
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 193..221
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 320..348
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REGION 1..61
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 503..523
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..45
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 523 AA; 57683 MW; 7139754FC7B59E9E CRC64;
MDRTAHRRAE YKSKGGLKQE ELRRRREEQQ VEIRRQKREE NISKRRNFLP SSGADSDDES
GVGTWELAED MVAGVFSDDP DRQLDATTRF RKLLSKEKNP PIERVIECGV VPRFVEFLRG
DNPMLQFEAA WALTNIASGT AEHTQVVINA QAVPEFIKLL SSPVPDVREQ AVWALGNIAG
DSPQCRDYVL QQGALRPLLN LLSENNKLSM LRNATWTLSN FCRGKSPQPD WDLISPALPV
LTKLIYSLDD EILIDACWAI SYLSDGSNDK IQAVIESGVC RRLVDLLMHP STSVQTPALR
SVGNIVTGDD LQTQVVITSG ALPALLSLLS SPKDGIRKEA CWTISNITAG SPQQIQAVID
ANIIPPLINI LQTADFKTKK EACWAISNAT SGGLQEPSQI RYLVSQGCIK PLCDLLQMMD
NKIIQVALDG LDNILKVGEM DKQAQGPGGV NQYALFVEEA GGMVTIHNLQ QHDNLEIYKK
AFNIMDKYFP DDEEAEPAVD ATGSFQFNPE GAAPPPGGFS FGQ
//
