ID   A0A371DUX9_9APHY        Unreviewed;       762 AA.
AC   A0A371DUX9;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   RecName: Full=Nucleoside phosphatase GDA1/CD39 {ECO:0008006|Google:ProtNLM};
GN   ORFNames=OH76DRAFT_1460067 {ECO:0000313|EMBL:RDX56346.1};
OS   Polyporus brumalis.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Polyporales; Polyporaceae; Polyporus.
OX   NCBI_TaxID=139420 {ECO:0000313|EMBL:RDX56346.1, ECO:0000313|Proteomes:UP000256964};
RN   [1] {ECO:0000313|EMBL:RDX56346.1, ECO:0000313|Proteomes:UP000256964}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BRFM 1820 {ECO:0000313|EMBL:RDX56346.1,
RC   ECO:0000313|Proteomes:UP000256964};
RX   PubMed=30061923; DOI=10.1186/s13068-018-1198-5;
RA   Miyauchi S., Rancon A., Drula E., Hage H., Chaduli D., Favel A., Grisel S.,
RA   Henrissat B., Herpoel-Gimbert I., Ruiz-Duenas F.J., Chevret D., Hainaut M.,
RA   Lin J., Wang M., Pangilinan J., Lipzen A., Lesage-Meessen L., Navarro D.,
RA   Riley R., Grigoriev I.V., Zhou S., Raouche S., Rosso M.N.;
RT   "Integrative visual omics of the white-rot fungus Polyporus brumalis
RT   exposes the biotechnological potential of its oxidative enzymes for
RT   delignifying raw plant biomass.";
RL   Biotechnol. Biofuels 11:201-201(2018).
CC   -!- SIMILARITY: Belongs to the GDA1/CD39 NTPase family.
CC       {ECO:0000256|ARBA:ARBA00009283, ECO:0000256|RuleBase:RU003833}.
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DR   EMBL; KZ857380; RDX56346.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A371DUX9; -.
DR   STRING; 139420.A0A371DUX9; -.
DR   Proteomes; UP000256964; Unassembled WGS sequence.
DR   GO; GO:0005794; C:Golgi apparatus; IEA:UniProt.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0017110; F:nucleoside diphosphate phosphatase activity; IEA:UniProt.
DR   Gene3D; 3.30.420.40; -; 1.
DR   Gene3D; 3.30.420.150; Exopolyphosphatase. Domain 2; 1.
DR   InterPro; IPR000407; GDA1_CD39_NTPase.
DR   PANTHER; PTHR11782; ADENOSINE/GUANOSINE DIPHOSPHATASE; 1.
DR   PANTHER; PTHR11782:SF121; NUCLEOSIDE-DIPHOSPHATASE MIG-23; 1.
DR   Pfam; PF01150; GDA1_CD39; 1.
DR   PROSITE; PS01238; GDA1_CD39_NTPASE; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|PIRSR:PIRSR600407-2};
KW   Hydrolase {ECO:0000256|RuleBase:RU003833};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Nucleotide-binding {ECO:0000256|PIRSR:PIRSR600407-2};
KW   Reference proteome {ECO:0000313|Proteomes:UP000256964};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        562..584
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          645..762
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        645..671
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        678..753
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   ACT_SITE        164
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR600407-1"
FT   BINDING         196..200
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR600407-2"
SQ   SEQUENCE   762 AA;  83707 MW;  21B73653EF43680A CRC64;
     MPPPTVVDPW FASRRFGVVI DAGSSGSRLQ IYSWKDARTV RLEQGADALR SLPQVGKGTE
     NGEEWSVKVE PGLSTFGDDP DGIGPYLVPL LEHARTHIPP SLQPDTPLFL LATAGMRLLA
     PEKQAEVLQT TCHFLKFHSN FKIDEPSAAG PCGSSVRIIT GEEEGLYGWV AVNYLMDGFK
     GSDDTPLTYG FLDMGGASTQ IAFEPSREEQ ERAQNLIDVR LRRLDGHDIN HKVFVTTWLG
     YGTNQARERY VGQLINEYEA NRTLSTGTEE QIDDPCLPKD LMLTNTPVQP DAASPHAKTP
     HKFVGTGSWE QCLERTLPLL NKDTPCPDSH CLFNGVYVPP IDFNASHFIG VSEYWYSSEQ
     SFGLGGPYDF VEYERAAAEF CAKDWTDILK GHEETRQKGH LGGDGEVEEG GVVVDTGKWG
     LDVEIRRLQM QCFKAAWIVN VLHEGIGMPR IVDPEGNSTT SGEKVAAQAQ TKGLGRPSFQ
     SMDSVGDIAI SWTLGKMVLE ASREVPAATA QARPIVDPLD DIPDISTSPV QPIRPPFIDF
     DAFEDKISHH LPHSLTRHSL GFSPIAFAFY LLICAFCAAT LYRMRHRIRG TVRRFVNKRD
     RSYLSEGFMM EEGLSLTGGA PASSPSRLSK FISPLTRLSS SLGLRASRPS PISVSREPSL
     RSGQYSPARV SPLRSFSFPP QPKGQNGLTV QDEPNGTATS YVPSSPRLPD GSFMSNGSVS
     SLQSRSRNSS HINLSSLAPR QTVSRTLTGM YHGQSASYRD EE
//