ID A0A371E705_MUCPR Unreviewed; 908 AA.
AC A0A371E705;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=PH, RCC1 and FYVE domains-containing protein 1 {ECO:0000313|EMBL:RDX61814.1};
DE Flags: Fragment;
GN Name=PRAF1 {ECO:0000313|EMBL:RDX61814.1};
GN ORFNames=CR513_59917 {ECO:0000313|EMBL:RDX61814.1};
OS Mucuna pruriens (Velvet bean) (Dolichos pruriens).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Mucuna.
OX NCBI_TaxID=157652 {ECO:0000313|EMBL:RDX61814.1, ECO:0000313|Proteomes:UP000257109};
RN [1] {ECO:0000313|EMBL:RDX61814.1, ECO:0000313|Proteomes:UP000257109}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Jos {ECO:0000313|Proteomes:UP000257109};
RC TISSUE=Seed {ECO:0000313|EMBL:RDX61814.1};
RA Nnadi N.E., Vos R., Hasami M.H., Devisetty U.K., Aguiy J.C.;
RT "Draft genome of Mucuna pruriens seed.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDX61814.1}.
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DR EMBL; QJKJ01015887; RDX61814.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A371E705; -.
DR STRING; 157652.A0A371E705; -.
DR Proteomes; UP000257109; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd13365; PH_PLC_plant-like; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 2.130.10.30; Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II; 3.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR027988; BRX_N.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR009091; RCC1/BLIP-II.
DR InterPro; IPR000408; Reg_chr_condens.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR22870; REGULATOR OF CHROMOSOME CONDENSATION; 1.
DR PANTHER; PTHR22870:SF358; REGULATOR OF CHROMOSOME CONDENSATION (RCC1) FAMILY WITH FYVE ZINC FINGER DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13713; BRX_N; 1.
DR Pfam; PF01363; FYVE; 1.
DR Pfam; PF16457; PH_12; 1.
DR Pfam; PF00415; RCC1; 6.
DR PRINTS; PR00633; RCCNDNSATION.
DR SMART; SM00064; FYVE; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF50985; RCC1/BLIP-II; 1.
DR PROSITE; PS00626; RCC1_2; 1.
DR PROSITE; PS50012; RCC1_3; 7.
DR PROSITE; PS50178; ZF_FYVE; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT REPEAT 245..306
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 307..358
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 359..413
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 414..465
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 479..529
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 530..581
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 582..633
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT DOMAIN 638..700
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT REGION 132..163
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 770..812
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 826..867
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 138..155
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 770..786
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 794..812
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:RDX61814.1"
SQ SEQUENCE 908 AA; 98737 MW; 14493C8C4578FB47 CRC64;
MADPPKTSLG ERDIEQAITS LKKGSYLLKY GRRGRPKFCP FRLSNDESLL LWYSGKEEKK
LKLSTVSRII PGQRTATFQR YPRPEKEYQS FSLIYSDRSL DLICKDKDEA EIWFVGLKAL
VTRSNSRKWR SESRTDDSLC SDSPQSGTRR SAPSITPFSD PGDAGGGAFD LQNRWVKAFS
EIISYTGASK SSSQAESIIN SSLSSGSADN SSNRNSASEA FRVSLSSAVS SSSQGSCHED
FDALGDVFIW GEGIGDGILV GGVHRVGAIS SSEMDAFLPK ALESKLVLDV HSIGCGYRHA
VIVTKQGEIF SWGEESGGRL GHGVEMDVFH PKLIDTLIGM NIELVACGEY HTCAVTYSGD
LYTWGDGTHN SGMLGHGNEV SHWIPKKVSG NLDGLRVSYV SCGPWHTAIV TSAGQLFTFG
DGTFGALGHG DNSSTNIPRE VETLKGLRTT RVACGVWHTA AVVEVINDSV ESSTHSSSGR
LYTWGDGDKS QLGHARGSRL VPECVVALGT ENICRVACGH SLTIALTTSG HVYTMGSTAY
GQLGCPSSDG KVPTRVEDKI ADSFVEDIAC GSYHVAVLTS KAEIYTWGKG LNGQLGHGDN
DHRNKPTFVV FLKDKQVKSV VCGSNFTAVV CLHKWIPSVD HSTCFGCHNL FNFRRKRHNC
YNCGLVFCKS CTSKKSIKAS LAPNSNKPYR VCDDCYLKLK KSAESVPLVQ TPSLRSVSMQ
VNRATKVQGT LLRLSSLSSI LQTESSQPKL PDSQDSHLFP ALNGKIQMRG FAPSKSSNSL
SGDSKKHLSV SEPAARISCQ STSPVSSKSS PRQSYEDINY LLKHKNDILS QEVISLRTQV
EDLTRKSESL EAELERTSKQ LKEVTAVAAD EAGKCKSAKE VIKSLTTQVG YSNCRVFPFL
LLYISKHD
//
