ID   A0A371E9Y6_MUCPR        Unreviewed;       478 AA.
AC   A0A371E9Y6;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   22-FEB-2023, entry version 12.
DE   SubName: Full=2-oxoisovalerate dehydrogenase subunit alpha 2, mitochondrial {ECO:0000313|EMBL:RDX62848.1};
DE   Flags: Fragment;
GN   ORFNames=CR513_58780 {ECO:0000313|EMBL:RDX62848.1};
OS   Mucuna pruriens (Velvet bean) (Dolichos pruriens).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC   NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Mucuna.
OX   NCBI_TaxID=157652 {ECO:0000313|EMBL:RDX62848.1, ECO:0000313|Proteomes:UP000257109};
RN   [1] {ECO:0000313|EMBL:RDX62848.1, ECO:0000313|Proteomes:UP000257109}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Jos {ECO:0000313|Proteomes:UP000257109};
RC   TISSUE=Seed {ECO:0000313|EMBL:RDX62848.1};
RA   Nnadi N.E., Vos R., Hasami M.H., Devisetty U.K., Aguiy J.C.;
RT   "Draft genome of Mucuna pruriens seed.";
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RDX62848.1}.
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DR   EMBL; QJKJ01015237; RDX62848.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A371E9Y6; -.
DR   STRING; 157652.A0A371E9Y6; -.
DR   Proteomes; UP000257109; Unassembled WGS sequence.
DR   GO; GO:0016624; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor; IEA:InterPro.
DR   CDD; cd02000; TPP_E1_PDC_ADC_BCADC; 1.
DR   Gene3D; 3.40.50.970; -; 1.
DR   InterPro; IPR001017; DH_E1.
DR   InterPro; IPR029061; THDP-binding.
DR   PANTHER; PTHR43380; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT ALPHA, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR43380:SF1; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT ALPHA, MITOCHONDRIAL; 1.
DR   Pfam; PF00676; E1_dh; 1.
DR   SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT   DOMAIN          143..438
FT                   /note="Dehydrogenase E1 component"
FT                   /evidence="ECO:0000259|Pfam:PF00676"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:RDX62848.1"
SQ   SEQUENCE   478 AA;  54059 MW;  8BA11A4DA5C41865 CRC64;
     NIMASWLLGR SRILTHGQHL HKNLSFLLGP LVNHGSFSSF RSTQSFKSND ASPGSLFCLS
     RRESTKAEAQ LDLEHHLTQD DPNQVIDFPG GKVGFTSEMK FISESAEKRV PCYRVLDDNG
     ELVKYSNYVQ VSKEMAVKMY SDMVTLQTMD SIFYEVQRQG RISFYLTSMG EEAVNIASAA
     ALAPDDIVLP QYREPGVLLW RGFTLQQFVH QCFGNTHDFG KGRQMPIHYG SNKHNYFTVS
     SPIATQLPQA VGAAYSLKMD GRSACAVTYC GDGGTSEGDF HAAMNFAAVR EAPVVFICRN
     NGWAISTPVE EQFRSDGIVV KGKAYGIWGI RVDGNDALAI FSAVHTAREI AIREKRPVLI
     EALTYRVGHH STSDDSTKYR PIDEIEYWKM ERNPVNRFKR WVERNGWWSD KDELELRSSI
     KKQLKDAMQV AEKAQKPPLE DLFTDVYDQL PSNLQEQERI LRKIIEKHPN DYPSDVPV
//