ID A0A371ESV4_MUCPR Unreviewed; 569 AA.
AC A0A371ESV4;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=cysteine--tRNA ligase {ECO:0000256|ARBA:ARBA00012832};
DE EC=6.1.1.16 {ECO:0000256|ARBA:ARBA00012832};
DE AltName: Full=Cysteinyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00031499};
DE Flags: Fragment;
GN Name=SYCO {ECO:0000313|EMBL:RDX69122.1};
GN ORFNames=CR513_51804 {ECO:0000313|EMBL:RDX69122.1};
OS Mucuna pruriens (Velvet bean) (Dolichos pruriens).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Mucuna.
OX NCBI_TaxID=157652 {ECO:0000313|EMBL:RDX69122.1, ECO:0000313|Proteomes:UP000257109};
RN [1] {ECO:0000313|EMBL:RDX69122.1, ECO:0000313|Proteomes:UP000257109}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Jos {ECO:0000313|Proteomes:UP000257109};
RC TISSUE=Seed {ECO:0000313|EMBL:RDX69122.1};
RA Nnadi N.E., Vos R., Hasami M.H., Devisetty U.K., Aguiy J.C.;
RT "Draft genome of Mucuna pruriens seed.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the class-I aminoacyl-tRNA synthetase family.
CC {ECO:0000256|ARBA:ARBA00005594}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDX69122.1}.
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DR EMBL; QJKJ01012247; RDX69122.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A371ESV4; -.
DR STRING; 157652.A0A371ESV4; -.
DR Proteomes; UP000257109; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004817; F:cysteine-tRNA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006423; P:cysteinyl-tRNA aminoacylation; IEA:InterPro.
DR CDD; cd00672; CysRS_core; 1.
DR Gene3D; 1.20.120.1910; Cysteine-tRNA ligase, C-terminal anti-codon recognition domain; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR HAMAP; MF_00041; Cys_tRNA_synth; 1.
DR InterPro; IPR015803; Cys-tRNA-ligase.
DR InterPro; IPR024909; Cys-tRNA/MSH_ligase.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR032678; tRNA-synt_1_cat_dom.
DR InterPro; IPR009080; tRNAsynth_Ia_anticodon-bd.
DR NCBIfam; TIGR00435; cysS; 1.
DR PANTHER; PTHR10890:SF3; CYSTEINE--TRNA LIGASE, CYTOPLASMIC; 1.
DR PANTHER; PTHR10890; CYSTEINYL-TRNA SYNTHETASE; 1.
DR Pfam; PF01406; tRNA-synt_1e; 1.
DR PRINTS; PR00983; TRNASYNTHCYS.
DR SUPFAM; SSF47323; Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases; 1.
DR SUPFAM; SSF52374; Nucleotidylyl transferase; 1.
PE 3: Inferred from homology;
KW Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:RDX69122.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 84..380
FT /note="tRNA synthetases class I catalytic"
FT /evidence="ECO:0000259|Pfam:PF01406"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:RDX69122.1"
SQ SEQUENCE 569 AA; 64439 MW; EBEBC059158096F8 CRC64;
MATVSLLKCY RPFFSTVFSH SAPPRPNAAF FRRSNLPSFC TASSSPPLTA EKDCGKSDGE
GLTLKNPSPE VWLHNTMSKT KEVFKPKVES KVGMYVCGVT AYDLSHIGHA RVYINFDLLY
RYFKHLGFEV CYVRNFTDVD DKIISRAKEL GEDPISLSRR YCEEFCRDMV TLNCLPPSVE
PKVSEHMPQI IDMIEKILSN GYAYIVDGDV YFNVEKFPEY GKLSSRDLED NRAGERVAVD
SRKKNPADFA LWKSAKPGEP FWESPWGPGR PGWHIECSAM SAAYLGYSFD IHGGGIDLVF
PHHENEIAQS CAACKKSDIS VWMHNGFVTV DSVKMSKSLG NFFTIRQVID VYHPLALRYF
LMSAHYRSPV NYSHIQLESA SDRVFYIYET LHECESFLNQ DDQTIRKDSI PPDTLNIIDK
FHDVFLTSMS DDLHTPVVLA GMSDPLKSIN DLLHTRKGKK QQFRIESLAA LEKSIRDVLT
VLGLIPTSYS EVLQQLKEKA LKRANLTEDE VLQKIEERAA ARIQKEYAKS DAIRKDLAVL
GITLMDSPSG TTWRPTIPLP LQEQQIDAL
//
