ID A0A371FKS4_MUCPR Unreviewed; 661 AA.
AC A0A371FKS4;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE SubName: Full=Trifunctional UDP-glucose {ECO:0000313|EMBL:RDX78927.1};
DE Flags: Fragment;
GN Name=RHM1 {ECO:0000313|EMBL:RDX78927.1};
GN ORFNames=CR513_40702 {ECO:0000313|EMBL:RDX78927.1};
OS Mucuna pruriens (Velvet bean) (Dolichos pruriens).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Mucuna.
OX NCBI_TaxID=157652 {ECO:0000313|EMBL:RDX78927.1, ECO:0000313|Proteomes:UP000257109};
RN [1] {ECO:0000313|EMBL:RDX78927.1, ECO:0000313|Proteomes:UP000257109}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Jos {ECO:0000313|Proteomes:UP000257109};
RC TISSUE=Seed {ECO:0000313|EMBL:RDX78927.1};
RA Nnadi N.E., Vos R., Hasami M.H., Devisetty U.K., Aguiy J.C.;
RT "Draft genome of Mucuna pruriens seed.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=NAD(+); Xref=ChEBI:CHEBI:57540;
CC Evidence={ECO:0000256|ARBA:ARBA00001911};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDX78927.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; QJKJ01008693; RDX78927.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A371FKS4; -.
DR STRING; 157652.A0A371FKS4; -.
DR Proteomes; UP000257109; Unassembled WGS sequence.
DR GO; GO:0008460; F:dTDP-glucose 4,6-dehydratase activity; IEA:InterPro.
DR GO; GO:0009225; P:nucleotide-sugar metabolic process; IEA:InterPro.
DR CDD; cd05246; dTDP_GD_SDR_e; 1.
DR CDD; cd05254; dTDP_HR_like_SDR_e; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR Gene3D; 3.90.25.10; UDP-galactose 4-epimerase, domain 1; 1.
DR InterPro; IPR005888; dTDP_Gluc_deHydtase.
DR InterPro; IPR016040; NAD(P)-bd_dom.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR029903; RmlD-like-bd.
DR PANTHER; PTHR43000; DTDP-D-GLUCOSE 4,6-DEHYDRATASE-RELATED; 1.
DR PANTHER; PTHR43000:SF22; NAD(P)-BD_DOM DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF16363; GDP_Man_Dehyd; 1.
DR Pfam; PF04321; RmlD_sub_bind; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
PE 4: Predicted;
KW NAD {ECO:0000256|ARBA:ARBA00023027}.
FT DOMAIN 14..319
FT /note="NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF16363"
FT DOMAIN 378..549
FT /note="RmlD-like substrate binding"
FT /evidence="ECO:0000259|Pfam:PF04321"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:RDX78927.1"
SQ SEQUENCE 661 AA; 75431 MW; B974F2385A488BA4 CRC64;
MSSKASMYEP KNILMTGAAG FIASHVTTRL IDKYPTYKIV ALDKLDYCST FKNLKSCASS
PNFKFIKGDI ASVDIVNHIM IEEEIDTIMH FAAQTHVDNS FGNSMEFTYN NIYGTHVLLE
ACRVTNCVKR FIHVSTDEVY GETDLEADIG NHEASQLLPT NPYSATKAGA EMLVMAYHRS
YGLPIITSRG NNVYGPNQYP EKLVPKFILL AMKGEKLPIH GDGSNVRSYL HCGDVAEAFD
VILHKGEIGQ IYNIGTKKER SVLDVAEEIC KLFKLNPKDV IEFVQDRPFN DKRYFLDDQK
LKLLGWRERT PWEEGLKMTI DWYKKNPDWW GDVSTALNPH PRFSAINLSD EAQWSFQYGY
SRLARSFTEV GRNNSGLKFL IYGRTGWIGG LLGKLCDEER IDWEYGKGRL EDRKSLIEDI
RRVKPSHVLS AAGVTGRPNV DWCESHKVET IRTNVVGTLT LADVCKEHGL YMMNFATGCI
FEYDKEHPLG SGIGFKEEDK PNFIGSFYSQ TKAMVEDLLK NYDNVCILRV RMPISSDLSN
PRNFITKISR YNKVVNIPNS MTVLDELLPI SIEMAKRNLR GIWNFTNPGV ISHNQILELY
RDYIDPKFKW ENFDLEEQAK VIVAPRSNNE MDASKIKKEF PNLLPIKDSI IKFVFEPNKK
T
//
