ID A0A371G7U1_MUCPR Unreviewed; 1594 AA.
AC A0A371G7U1;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=Reverse transcriptase domain-containing protein {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=CR513_32028 {ECO:0000313|EMBL:RDX86622.1};
OS Mucuna pruriens (Velvet bean) (Dolichos pruriens).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Mucuna.
OX NCBI_TaxID=157652 {ECO:0000313|EMBL:RDX86622.1, ECO:0000313|Proteomes:UP000257109};
RN [1] {ECO:0000313|EMBL:RDX86622.1, ECO:0000313|Proteomes:UP000257109}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Jos {ECO:0000313|Proteomes:UP000257109};
RC TISSUE=Seed {ECO:0000313|EMBL:RDX86622.1};
RA Nnadi N.E., Vos R., Hasami M.H., Devisetty U.K., Aguiy J.C.;
RT "Draft genome of Mucuna pruriens seed.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDX86622.1}.
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DR EMBL; QJKJ01006464; RDX86622.1; -; Genomic_DNA.
DR Proteomes; UP000257109; Unassembled WGS sequence.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd01647; RT_LTR; 1.
DR Gene3D; 3.30.70.270; -; 2.
DR Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR Gene3D; 4.10.60.10; Zinc finger, CCHC-type; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR000477; RT_dom.
DR InterPro; IPR001878; Znf_CCHC.
DR InterPro; IPR036875; Znf_CCHC_sf.
DR PANTHER; PTHR48347; REVERSE TRANSCRIPTASE; 1.
DR PANTHER; PTHR48347:SF1; REVERSE TRANSCRIPTASE; 1.
DR Pfam; PF00078; RVT_1; 1.
DR SMART; SM00343; ZnF_C2HC; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF57756; Retrovirus zinc finger-like domains; 1.
DR PROSITE; PS50878; RT_POL; 1.
DR PROSITE; PS50158; ZF_CCHC; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00047};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00047};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00047}.
FT DOMAIN 723..739
FT /note="CCHC-type"
FT /evidence="ECO:0000259|PROSITE:PS50158"
FT DOMAIN 1008..1190
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
FT REGION 47..87
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 159..180
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 322..375
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 414..434
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1541..1574
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 216..284
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 47..66
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 67..87
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 336..354
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 361..375
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:RDX86622.1"
SQ SEQUENCE 1594 AA; 184358 MW; C49FA01C01D6E669 CRC64;
MIRPYVKEGK IPIWGVRPNG EEIYTDKING HFIWDVDPSM CDSDCDCYYD DPDDDNQDEE
VDSSDDEDER PCKPYPPPRR DRDPMEKPWV GIHRQRKPDP DWIHKRGLEI LQERNLLPTT
SCIKKIISPV MEKIPSPIPC MMFTEADFPP MERKVDVTTK VTTKPHISSS EIGTDGRPKP
LSQAEEVLNW QTENARAQNL LLKKIDDKVN KISSTVDKCD ERLEVLSERM RKLYHQLTAE
ISKNEEEWRK LKFGEESNKK EREVRRLKAE LYELENYIER KMRERQEERE SSLRGSSSYM
TSSIHVSPMF LPPPESFFIP PPKPWALPTS TPFRESRRPE SSKRTTRRDS PEPLYEDTSV
PQHKPSDSGK NVFQDSQDPY EQFTVKIYDA EASSSNNSSD TEDTQSTYHI ENIGEQEESD
SAETNSEADN ESDNPEKILD QAILMANTTD HSETIYDDED EVISPLPNNS TKPSSGPWFT
LDDVPPRQWR RRLIEFGAWL DTKLMRDPDS YKVIEEFCCR MTGTLKEWYH HLGAVRQNQL
HEQGSSAAIL GILHEEFMGD TGPIDKKIRD EYYTMKCCSL KVKDLDTHFQ RMLKRFYLLN
GLNDPSLKNT YVASLPDRLQ PEINRMAMAT QKEFSTMSMG QIHQMTQEAL DKLCQQHQYI
SDVLKEKGEF SKACKKPYLG IKCKEKTCSC SSKKKKSYSF PKKKKKYKFF KKKQKRGKPS
DQRCFICGKK GHYSRTCPNK ADKAIKLISS LDIDDEDVES IYSEQSTADE ETVFALGYSD
GDQSDTESIP IFSTTQVQSI VVSPPQPGIE IQLLPSKYQR PIKAIAYMDT GAQKTMMNPD
ILPKEAWKKE YSYFIAADGE VFITDLISVN PIGICFSPDC IVWSKVIGTK LPDRDILIGM
DVFSKAASLQ IHSTGIKYKR EFKPFSKILK IFSVQEDDGT KEIKNKLLSM CADSHESFPH
PNPLWKNEDF FIRLPFKLNE DINPTKATHP GMSPSHLLLA KQECLELLKQ GLIEPTQSNW
ACQAFYVEKR SERLRGKKRL VIDYKPLNHF LQDDKFPIPK ASSLPILLRE SNIFSKFDLK
SGFWRLGIHP EERYKTAFCI PNAQYQWKVL PFGLKVAPSL FQKAMIRIFD PIMENAIIYI
DDILIFSKDM DSHKKLLEKF FDIINQHGIM LSERKIYLFK TEIDFLGMHF SQGCYQPQPH
IAEELKKFPD HSLTIKQTQQ FLGIVNYIRD FIPHVAKYVS PLTRLLKKDP PSWGTEQTRA
IQELKKIAQS PPALKIPGEG DRILQTNASD DFWGAKFDFH LRSFRFEVQM DNSSFPKILE
FKNKMPPDPQ ILRLKDWFSR YNFSVKHIKG KNNIIPDMLS RPNKVIQVIS SYHTFPLIYM
MKSLSNMAKT SKDFPPGLNP KTVEDILEYV ETHYFHFIHL TMKYKVTASF MFNPKNPYGG
IFELFCNIGW DLCEPTLWAI WCKTIKKTFF SGHYWNGSLL YNGGEMSSGG LSCLKKEEDF
QEKNIRSHNI AYSWGTFEEY PLDESYSTQL SMHLREINSF KKSPENTAPD NLNRRLIPAS
NQGQQQPSSS KTTTEYFISE ETGHQEIGHQ ENAI
//
