ID A0A371GFX3_MUCPR Unreviewed; 1112 AA.
AC A0A371GFX3;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=PH, RCC1 and FYVE domains-containing protein 1 {ECO:0000313|EMBL:RDX89469.1};
DE Flags: Fragment;
GN Name=PRAF1 {ECO:0000313|EMBL:RDX89469.1};
GN ORFNames=CR513_28800 {ECO:0000313|EMBL:RDX89469.1};
OS Mucuna pruriens (Velvet bean) (Dolichos pruriens).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Mucuna.
OX NCBI_TaxID=157652 {ECO:0000313|EMBL:RDX89469.1, ECO:0000313|Proteomes:UP000257109};
RN [1] {ECO:0000313|EMBL:RDX89469.1, ECO:0000313|Proteomes:UP000257109}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Jos {ECO:0000313|Proteomes:UP000257109};
RC TISSUE=Seed {ECO:0000313|EMBL:RDX89469.1};
RA Nnadi N.E., Vos R., Hasami M.H., Devisetty U.K., Aguiy J.C.;
RT "Draft genome of Mucuna pruriens seed.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDX89469.1}.
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DR EMBL; QJKJ01005662; RDX89469.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A371GFX3; -.
DR STRING; 157652.A0A371GFX3; -.
DR Proteomes; UP000257109; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd00065; FYVE_like_SF; 1.
DR CDD; cd13365; PH_PLC_plant-like; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 2.130.10.30; Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II; 2.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR013591; Brevis_radix_dom.
DR InterPro; IPR027988; BRX_N.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR009091; RCC1/BLIP-II.
DR InterPro; IPR000408; Reg_chr_condens.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR22870; REGULATOR OF CHROMOSOME CONDENSATION; 1.
DR PANTHER; PTHR22870:SF91; REGULATOR OF CHROMOSOME CONDENSATION (RCC1) FAMILY WITH FYVE ZINC FINGER DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF08381; BRX; 1.
DR Pfam; PF13713; BRX_N; 1.
DR Pfam; PF01363; FYVE; 1.
DR Pfam; PF16457; PH_12; 1.
DR Pfam; PF00415; RCC1; 6.
DR PRINTS; PR00633; RCCNDNSATION.
DR SMART; SM00064; FYVE; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF50985; RCC1/BLIP-II; 1.
DR PROSITE; PS51514; BRX; 1.
DR PROSITE; PS00626; RCC1_2; 3.
DR PROSITE; PS50012; RCC1_3; 7.
DR PROSITE; PS50178; ZF_FYVE; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..1112
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5016877137"
FT REPEAT 229..290
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 291..342
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 343..397
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 398..449
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 461..512
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 513..564
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 565..616
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT DOMAIN 621..683
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT DOMAIN 1034..1089
FT /note="BRX"
FT /evidence="ECO:0000259|PROSITE:PS51514"
FT REGION 140..171
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 775..809
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 971..1027
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1090..1112
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 817..893
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 778..795
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 989..1005
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:RDX89469.1"
SQ SEQUENCE 1112 AA; 120752 MW; 8B33D4AF3739477D CRC64;
LPCYFFILQA LIVLKKGAQL LKYGRKGKPK FCPFRLSNDE LSLIWISSSG EKNLKLSSVS
RIIPGQRTAV FQQYLHPEKD YLSFSLIYNN GKRSLDLICK DKVEAEVWIA GLKALISSGQ
GGRSKIDGWS DGGLYLDDSR DLTSNSPSES SVSASREISS PDVSVSLPNT SPQSFYSENT
FNFERSHAPS NPSNMQVKGS SSDVFRVSVS SAPSTSSHGS APDDYDALGD VYIWGEVICE
NVVKVGAEKN TSYFSPRADI LLPRPLESNV VLDVLQIACG VKHAALVTRQ GELFTWGEES
GGRLGHGVGK NVVQPRLVEA MTSTTVDFVA CGEFHTCAVT MAGELYTWGD GTHNAGLLGH
GTDVSHWIPK RIAGPLEGLQ VALVTCGPWH TALITSTGQL FTFGDGTFGV LGHGDRENVS
YPREVESLSG LRTIAVACGV WHTAAVVEVI VTQSSASVSS GKLFTWGDGD KNRLGHGDKD
ARLEPTCVPS LIDYNFHRIA CGHSLTVGLT TSGHVFTMGS TVYGQLGSPQ SDGKLPCLVE
DKLAGESVEE IACGAYHVAV LTSKNEVYTW GKGANGRLGH GDVEDRKTPT LVEALKDRHV
KYIACGSNYS AAICLHKWVS GAEQSQCSAC RQAFGFTRKR HNCYNCGLVH CHSCSSRKAL
RAALAPNPGK PYRVCDSCFV KLNKVAELGN NNRRNAMPRL SGENKDRLEK SELRLTKTAV
PSNMDLIKQL DSKAAKQGKK ADTFSLVRTS QAPSLLQLKD VVLSTAIDLK RTAPRPVLTP
SGVSSRSVSP FSRRPSPPRS ATPIPTTSGL SFSKSIADSL KKTNELLNQE VLKLRSQVET
LRQRCELQEL ELQRSAKKTQ EAMALAADES AKSKAAKEVI KSLTAQLKDL AERLPPGTYD
AENIRPAYLP NGLEPNGIHY PDLNGERHNR AESISGSSLA SIALESSLMN RTEGTSPGSY
GANLYQQNRE SVTSNGTDDY PDVKLPNGSG MIQASSSTVS DTVDGRDSGH FQDDESALRS
KNATSPANSN QIEAEWIEQY EPGVYITLVA LRDGTRDLKR VRFSRRRFGE HQAETWWSEN
RDKVYERYNV RSTDKSSGQA GRRAEGAGSP VL
//
