ID A0A371H3L4_MUCPR Unreviewed; 656 AA.
AC A0A371H3L4;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00012418};
DE EC=2.7.7.6 {ECO:0000256|ARBA:ARBA00012418};
DE Flags: Fragment;
GN Name=NRPA1 {ECO:0000313|EMBL:RDX97276.1};
GN ORFNames=CR513_19961 {ECO:0000313|EMBL:RDX97276.1};
OS Mucuna pruriens (Velvet bean) (Dolichos pruriens).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Mucuna.
OX NCBI_TaxID=157652 {ECO:0000313|EMBL:RDX97276.1, ECO:0000313|Proteomes:UP000257109};
RN [1] {ECO:0000313|EMBL:RDX97276.1, ECO:0000313|Proteomes:UP000257109}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Jos {ECO:0000313|Proteomes:UP000257109};
RC TISSUE=Seed {ECO:0000313|EMBL:RDX97276.1};
RA Nnadi N.E., Vos R., Hasami M.H., Devisetty U.K., Aguiy J.C.;
RT "Draft genome of Mucuna pruriens seed.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000256|ARBA:ARBA00024550};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDX97276.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; QJKJ01003693; RDX97276.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A371H3L4; -.
DR STRING; 157652.A0A371H3L4; -.
DR Proteomes; UP000257109; Unassembled WGS sequence.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR Gene3D; 4.10.860.120; RNA polymerase II, clamp domain; 1.
DR InterPro; IPR045867; DNA-dir_RpoC_beta_prime.
DR InterPro; IPR007080; RNA_pol_Rpb1_1.
DR InterPro; IPR044893; RNA_pol_Rpb1_clamp_domain.
DR PANTHER; PTHR19376; DNA-DIRECTED RNA POLYMERASE; 1.
DR PANTHER; PTHR19376:SF11; DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA1; 1.
DR Pfam; PF04997; RNA_pol_Rpb1_1; 1.
DR SUPFAM; SSF64484; beta and beta-prime subunits of DNA dependent RNA-polymerase; 1.
PE 4: Predicted;
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478,
KW ECO:0000313|EMBL:RDX97276.1};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 10..239
FT /note="RNA polymerase Rpb1"
FT /evidence="ECO:0000259|Pfam:PF04997"
FT REGION 231..258
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:RDX97276.1"
SQ SEQUENCE 656 AA; 73515 MW; FBB09BEB194E2F0E CRC64;
MVLTTEGATN AVEAVAFSFL TDDELRRSSR VKITNSILLD ALMHPVPAGL YDAAMGPLDD
KSLCKSCGQT SKHCPGHFGH IELVSPVYNP LMFNILSNIL QRTCFSCHHF QASRQAVDMR
TSQLELIMKG DIIGAKNLDS ISPHESIHPG DDGDESQCCA EQLGENWTSL QFSEAVSVLR
KFLMRKYKKC QNCGVINPRI SKPTYGWFHM NVLSADQARA NTIRAVGSKT TNDDISLGGG
DTTDEEDITS AGTAKRDNRK NGKLSYKLAA QNKLSGSLLP SQVKGILELL WENETRLCSY
ISDIQDQGFG KKAGHSMFFL ENIFVPPIKF RPPTKGGDNC IQPAYRLNGK NYLKWAQLVC
TTLKGKGKIN HLTGARQKER DPNFTTWDEE DSWIITWLWN SMDTKISDTI ILLSTTKEIW
DAIEKTYSKA KDVAQVYDVK VKIVAAKQDN KFVTEYANQL KLFWMELDHY REIKTKCVED
VAVLKEFIEQ DRVYDFLVGL NPEFDLVRIL GNEESRRNLM LDSPVVESST MVAENVKNGQ
PKKTDEGREG MRAFFNSLEK PLGTCTLAYL GMLPLSFGFN VSKALPSLWS HKPYDPSSKY
FTYSPCPNNK KLVTIDDTLV TVASIGNIQI NLSIALKIVH HNPKLSTNLV SAKTYK
//
