ID A0A371HK43_MUCPR Unreviewed; 1054 AA.
AC A0A371HK43;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Protein PIN-LIKES 3 {ECO:0000313|EMBL:RDY03082.1};
DE Flags: Fragment;
GN Name=PILS3 {ECO:0000313|EMBL:RDY03082.1};
GN ORFNames=CR513_13373 {ECO:0000313|EMBL:RDY03082.1};
OS Mucuna pruriens (Velvet bean) (Dolichos pruriens).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Mucuna.
OX NCBI_TaxID=157652 {ECO:0000313|EMBL:RDY03082.1, ECO:0000313|Proteomes:UP000257109};
RN [1] {ECO:0000313|EMBL:RDY03082.1, ECO:0000313|Proteomes:UP000257109}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Jos {ECO:0000313|Proteomes:UP000257109};
RC TISSUE=Seed {ECO:0000313|EMBL:RDY03082.1};
RA Nnadi N.E., Vos R., Hasami M.H., Devisetty U.K., Aguiy J.C.;
RT "Draft genome of Mucuna pruriens seed.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in cellular auxin homeostasis by regulating auxin
CC metabolism. Regulates intracellular auxin accumulation at the
CC endoplasmic reticulum and thus auxin availability for nuclear auxin
CC signaling. {ECO:0000256|ARBA:ARBA00025100}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the auxin efflux carrier (TC 2.A.69.2) family.
CC {ECO:0000256|ARBA:ARBA00025752}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDY03082.1}.
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DR EMBL; QJKJ01002388; RDY03082.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A371HK43; -.
DR STRING; 157652.A0A371HK43; -.
DR Proteomes; UP000257109; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0009734; P:auxin-activated signaling pathway; IEA:UniProtKB-KW.
DR GO; GO:0080162; P:endoplasmic reticulum to cytosol auxin transport; IEA:InterPro.
DR InterPro; IPR004776; Mem_transp_PIN-like.
DR InterPro; IPR045033; PILS1/3/4/5/7.
DR PANTHER; PTHR31651:SF45; AUXIN EFFLUX CARRIER FAMILY PROTEIN; 1.
DR PANTHER; PTHR31651; TRANSPORTER; 1.
DR Pfam; PF03547; Mem_trans; 3.
PE 3: Inferred from homology;
KW Auxin signaling pathway {ECO:0000256|ARBA:ARBA00023294};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 42..61
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 73..94
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 106..127
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 147..168
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 251..273
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 293..314
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 326..346
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 393..416
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 428..452
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 495..519
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 531..548
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 639..666
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 678..696
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 708..730
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 742..763
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 783..804
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 894..913
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 933..953
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 965..985
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1005..1026
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1033..1053
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT NON_TER 1054
FT /evidence="ECO:0000313|EMBL:RDY03082.1"
SQ SEQUENCE 1054 AA; 115819 MW; 6ABF04A8B5136EA7 CRC64;
MDFWKLFVVA LMPVLKVLLI TAVGTILAIN RFNILGETAR KNLNTMVFFV FSPTLVCSSL
AETITLRNVV ILWFMPLNIL LTFIIGTILG LIVVKLTRVP HHLQGLVLGC CAAGNLGNLP
IIIVPAVCKQ SHSPFGDVNV CYKNALAYAS LSMALGSIYI WSYAYNLVRL YSPKISNEVK
VDDGSMIINP VCAIKTDPEN PLTCSRGLPI ETDEDRVKHF QIQCSVHDGQ VDEVPKKKMI
MKQLITLVQK VNLKVLFTPS TIGAIVGLII GVVPQFRKLL IGDSAPLHVI EDSVVMLGYA
CIPAMTLLVG ANLIKGLNGL GEHFPFIVGI TVVRCVALPA IGVGIVKGAV HFGLIHPDPL
YEFLLLLQFA LPPAVSMSTI TQLFGAGEGE CSVIMFATYS CAAVSVTLWC TFFMWLKRKE
RNRINMDIWK LFVIALMPNV KVLLITLVGS ILAINRFDIL GETATKNMNT MVYYVLSPAL
AWSSLAKTIT LRSMITLWFM PICIILTVII GTALGWLLVK ITRVPYHLRG LVMGCCAVGS
ILAWPYAFNI VRIYSTQVIS NIVKVDEFTV NPTCETKSDP ENLSKCSTQT LVTTEDRSHS
NNCMNQLEIE TVVPVGKMQL EGTISTYIDW SDKFHNMDFW KLFIVSFTSI MKLLLITALG
AFLAHHRFNL LKQNARKHIN AMVYFVFTPA LIYSSMSNTI TLRSMVMLWF MPFSILVTYV
AGTVLGWLLI KIIRVPHHLH GLVLGCCAAG NLASLPLIVV PSLCKHRNSP FGDVAVCYRN
GLAYASLSMA VGYTYAWSIT FNVVRIYTPK TSNVCKVDES TVNPMSATET DPENLLKCPC
GALVMAKDIA KPNGGMDQPQ IECKVPDGQA KVPEKLKIMK QLKILADKIN NMKILIAPST
MAAILGLTIG VVPQFRELLV GDSALFHVVQ DSITMLGDAS VPAMVLLLGA NLVEGLKGVR
KQLPLIVGII MVKFVALPAI GIGIVKGAVH FKLIHPDPLY QFVLLLQYAL PPAIVMSTMT
QMFGVGEGEC STIMLATYSC AAIMLTLWCT MFMW
//
