ID A0A371HTQ6_MUCPR Unreviewed; 688 AA.
AC A0A371HTQ6;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=Terpene cyclase/mutase family member {ECO:0000256|RuleBase:RU362003};
DE EC=5.4.99.- {ECO:0000256|RuleBase:RU362003};
GN Name=GgCAS1 {ECO:0000313|EMBL:RDY06175.1};
GN ORFNames=CR513_09882 {ECO:0000313|EMBL:RDY06175.1};
OS Mucuna pruriens (Velvet bean) (Dolichos pruriens).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Mucuna.
OX NCBI_TaxID=157652 {ECO:0000313|EMBL:RDY06175.1, ECO:0000313|Proteomes:UP000257109};
RN [1] {ECO:0000313|EMBL:RDY06175.1, ECO:0000313|Proteomes:UP000257109}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Jos {ECO:0000313|Proteomes:UP000257109};
RC TISSUE=Seed {ECO:0000313|EMBL:RDY06175.1};
RA Nnadi N.E., Vos R., Hasami M.H., Devisetty U.K., Aguiy J.C.;
RT "Draft genome of Mucuna pruriens seed.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the terpene cyclase/mutase family.
CC {ECO:0000256|ARBA:ARBA00009755, ECO:0000256|RuleBase:RU362003}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDY06175.1}.
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DR EMBL; QJKJ01001733; RDY06175.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A371HTQ6; -.
DR STRING; 157652.A0A371HTQ6; -.
DR Proteomes; UP000257109; Unassembled WGS sequence.
DR GO; GO:0005811; C:lipid droplet; IEA:InterPro.
DR GO; GO:0031559; F:oxidosqualene cyclase activity; IEA:UniProt.
DR GO; GO:0016104; P:triterpenoid biosynthetic process; IEA:InterPro.
DR CDD; cd02892; SQCY_1; 1.
DR Gene3D; 1.50.10.20; -; 2.
DR InterPro; IPR032696; SQ_cyclase_C.
DR InterPro; IPR032697; SQ_cyclase_N.
DR InterPro; IPR018333; Squalene_cyclase.
DR InterPro; IPR008930; Terpenoid_cyclase/PrenylTrfase.
DR NCBIfam; TIGR01787; squalene_cyclas; 1.
DR PANTHER; PTHR11764:SF20; LANOSTEROL SYNTHASE; 1.
DR PANTHER; PTHR11764; TERPENE CYCLASE/MUTASE FAMILY MEMBER; 1.
DR Pfam; PF13243; SQHop_cyclase_C; 2.
DR Pfam; PF13249; SQHop_cyclase_N; 1.
DR SUPFAM; SSF48239; Terpenoid cyclases/Protein prenyltransferases; 2.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|RuleBase:RU362003};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 129..353
FT /note="Squalene cyclase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF13249"
FT DOMAIN 383..510
FT /note="Squalene cyclase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13243"
FT DOMAIN 551..680
FT /note="Squalene cyclase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13243"
SQ SEQUENCE 688 AA; 78702 MW; 481CCC3E1D2D892F CRC64;
MWKLKIAEGG SPWLRTLNNH VGRQVWEFDP NLGSPQDLLE IENARQNFHD NRFTRKHSAD
LLMRMQFARE NPIPEVLPKV GVIDIEDVTD EIVTRTLRRA VSFHSTLQSY DGHWPGDYGG
PMFLMPGLNK DGGWGLHIEG PSTMFGSVLS YVTLRLLGEG PNDGEGEMEK ARDWILGHGG
ATYITSWGKM WLSVLGVHEW SGNNPLPPEI WLLPYMLPFH PGRMWCHCRM VYLPMSYLYG
KRFVGPITPT VLSLRKELYT TPYHDIDWNQ ARNLCAKEDL YYPHPLVQDI LWASLHNFLE
PILMHWPGKK LREKAIRTAI EHIHYEDENT RYICIGPVNK VLNMLCCWVE DPNSEAFKLH
LPRIYDYLWI AEDGMKMQGY NGSQLWDTAF AVQAIISTNL VEEFGPTIRK AHTYIKNAQV
LEDCPGDLNK WYRHISKGAW PFSTADHGWP ISDCTAEGLK AVLSLSKIAP EIVGEPLEVK
RLYDAVNVLL SLQNEDGGFA TYELKRSYDW LERQFKLWHH LGNYILGIAE KKYNVVLRKP
RPSLKKYKLR MVHGLIAAGR SFSNCSSIHK ACEFLLSKQL PSGGWGESYL SCQNKVYSNL
EGNRSHVVNT GYALLALIDA GQAKIDPTPL HRAAAYLINS QLEDGDFPQQ EIMGVFNKNC
MITFAAYRNI FPIWALGEYR SRVLVEAR
//
