ID A0A371IRY9_9FIRM Unreviewed; 224 AA.
AC A0A371IRY9;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Deoxynucleoside kinase {ECO:0000313|EMBL:RDY23234.1};
GN ORFNames=CHF27_009290 {ECO:0000313|EMBL:RDY23234.1};
OS Romboutsia maritimum.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Peptostreptococcaceae;
OC Romboutsia.
OX NCBI_TaxID=2020948 {ECO:0000313|EMBL:RDY23234.1, ECO:0000313|Proteomes:UP000243494};
RN [1] {ECO:0000313|EMBL:RDY23234.1, ECO:0000313|Proteomes:UP000243494}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCRI-22766 {ECO:0000313|EMBL:RDY23234.1,
RC ECO:0000313|Proteomes:UP000243494};
RX PubMed=29025937;
RA Maheux A.F., Boudreau D.K., Berube E., Boissinot M., Raymond F.,
RA Brodeur S., Corbeil J., Brightwell G., Broda D., Omar R.F., Bergeron M.G.;
RT "Draft Genome Sequence of Romboutsia maritimum sp. nov. Strain CCRI-
RT 22766(T), Isolated from Coastal Estuarine Mud.";
RL Genome Announc. 5:e01044-17(2017).
CC -!- SIMILARITY: Belongs to the DCK/DGK family.
CC {ECO:0000256|ARBA:ARBA00007420}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDY23234.1}.
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DR EMBL; NOJZ02000016; RDY23234.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A371IRY9; -.
DR OrthoDB; 9776634at2; -.
DR Proteomes; UP000243494; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0019136; F:deoxynucleoside kinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd01673; dNK; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR002624; DCK/DGK.
DR InterPro; IPR031314; DNK_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10513; DEOXYNUCLEOSIDE KINASE; 1.
DR PANTHER; PTHR10513:SF15; NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 10, MITOCHONDRIAL; 1.
DR Pfam; PF01712; dNK; 1.
DR PIRSF; PIRSF000705; DNK; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|PIRSR:PIRSR000705-3};
KW Kinase {ECO:0000313|EMBL:RDY23234.1};
KW Nucleotide-binding {ECO:0000256|PIRSR:PIRSR000705-3};
KW Reference proteome {ECO:0000313|Proteomes:UP000243494};
KW Transferase {ECO:0000313|EMBL:RDY23234.1}.
FT DOMAIN 18..214
FT /note="Deoxynucleoside kinase"
FT /evidence="ECO:0000259|Pfam:PF01712"
FT ACT_SITE 93
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000705-1"
FT BINDING 22..30
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PIRSR:PIRSR000705-3"
FT BINDING 46
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000705-2"
FT BINDING 58
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000705-2"
FT BINDING 69
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000705-2"
FT BINDING 94
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000705-2"
FT BINDING 99
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000705-2"
FT BINDING 151..155
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PIRSR:PIRSR000705-3"
FT BINDING 160
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000705-2"
SQ SEQUENCE 224 AA; 26386 MW; 07AFA7224957C001 CRC64;
MFKLVNQCNK PLSRDLFITV AGNVGAGKST LTKLVGEKLG FETHFEKVDG NPYLEDFYLD
QEKWGFHLQL YFLAQRFKQQ KEIDNNGLNN IQDRSIYEDV EIFARNLFDN KKMSKRDYIT
YRDLFNDMVP HLRRPDLMIY LNGSIDTIVN RINLRGREME KSVDINYWKN LHNRYERWIG
EYSQSPVLYV NINEIDIINN PEHLDLLCNE IKKALGIGAV SKIQ
//
