ID A0A371J5A6_9FIRM Unreviewed; 2744 AA.
AC A0A371J5A6;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=DUF5011 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CHL78_007645 {ECO:0000313|EMBL:RDY27868.1};
OS Romboutsia weinsteinii.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Peptostreptococcaceae;
OC Romboutsia.
OX NCBI_TaxID=2020949 {ECO:0000313|EMBL:RDY27868.1, ECO:0000313|Proteomes:UP000215694};
RN [1] {ECO:0000313|EMBL:RDY27868.1, ECO:0000313|Proteomes:UP000215694}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCRI-19649 {ECO:0000313|EMBL:RDY27868.1,
RC ECO:0000313|Proteomes:UP000215694};
RX PubMed=28982987;
RA Maheux A.F., Boudreau D.K., Berube E., Boissinot M., Cantin P., Raymond F.,
RA Corbeil J., Omar R.F., Bergeron M.G.;
RT "Draft Genome Sequence of Romboutsia weinsteinii sp. nov. Strain CCRI-
RT 19649(T) Isolated from Surface Water.";
RL Genome Announc. 5:e00901-17(2017).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the protein prenyltransferase subunit beta
CC family. {ECO:0000256|ARBA:ARBA00010497}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDY27868.1}.
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DR EMBL; NOJY02000010; RDY27868.1; -; Genomic_DNA.
DR OrthoDB; 3171015at2; -.
DR Proteomes; UP000215694; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008318; F:protein prenyltransferase activity; IEA:InterPro.
DR CDD; cd00688; ISOPREN_C2_like; 4.
DR Gene3D; 1.50.10.20; -; 6.
DR Gene3D; 2.60.40.10; Immunoglobulins; 5.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR025875; Leu-rich_rpt_4.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR001330; PFTB_repeat.
DR InterPro; IPR045089; PGGT1B-like.
DR InterPro; IPR008930; Terpenoid_cyclase/PrenylTrfase.
DR PANTHER; PTHR11774; GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT; 1.
DR PANTHER; PTHR11774:SF11; GERANYLGERANYL TRANSFERASE TYPE-2 SUBUNIT BETA; 1.
DR Pfam; PF12799; LRR_4; 2.
DR Pfam; PF00432; Prenyltrans; 6.
DR SMART; SM00365; LRR_SD22; 4.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF48239; Terpenoid cyclases/Protein prenyltransferases; 6.
DR PROSITE; PS51450; LRR; 3.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Prenyltransferase {ECO:0000256|ARBA:ARBA00022602};
KW Reference proteome {ECO:0000313|Proteomes:UP000215694};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT TRANSMEM 2721..2739
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 2650..2719
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 61..91
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1471..1498
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 2652..2668
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2679..2706
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2744 AA; 306111 MW; 1D0F9B5F8D8FD363 CRC64;
MEKSKTKKVI SMATTSVIVG NILIPSAVSA EEAISESISE IPINIEENDK IQQDNDLPSE
NLQEESEINQ QEENLEKIDD LETENSTIKE KESQKTVEES AKDLIKYYQS NRDLMSYEDI
LGLELLGEKI EDYNVNKIHI NASGISESSN TLNHAITILG LVALGENPRD YKGKDLVELL
EAKQNYTGGF NDDGPNKKST SASIIALETV KSKKYDKQKA VDFILEKQKE DGSINYDLGG
SVDAFKAFNK LDESSKIKEA KDKIINYLIS TIKSNDGEEL DNTEKLEVYY VLNQCDVEKD
IYSHLLQEVI DSQREDGGFA LYPDYSNPFG ITNYTASYVF AKELTGKDIY DELDKKYAKI
DISNDISKIP ESMESAIKYL ETESSFGVAQ WYEMLGLYAG EADWSKFEKK TSFYDNINKI
NEGSSEEVIA QAILGLVADG KDPSNYEGKD LINILKNKQK DDGSFGNAIK TGYSILALQV
TNTNFNKDSA IQYLLNNQHE NGYIMDYFGD ADNEATTISL IALSQMRESS NIEKFKNKAI
DYILSIKNDI SKAGRPTNDL SLSILALAAN KIDKSQYADL VDTLLKQQKK TSSMAGSFYR
TIQEDTYSID NNHEADSYII DFASGATCYA LMALNSVDKN VNFLERLNQD YEELTGKKEP
ITIDESIERV KNYYNKNNLL KEWGSIVGLS SLGVDIYNSD LSAVMFGSSL KNITADSDST
DIANSVLGII GLNENPKDYH NKNFVKLLKN RQKEDGSFEG SSIDSTLNAI IALEITDESY
NRDLAKSYIL DNINDDKNIN NDYYSSALAI TALSFFEGED VSLAREDIIK YLIENKEEIK
GDIRLSNTVV LSLNINNVEY SNYESIVEYM QNTQLDDGSY PIKDRDNETN IEATYSSMMT
LASIKNNKNV YNYLDDKYTG SDNQEHEEIR TPQKSISRVI NVYKNISKIN RSTEEILGLY
YSNEDLNKYK KNEFSKDSVN ASTLAKKDAL NILELVATGK DPKAYKGKQN ALIKSNRTTN
WVDILEKKQD SNGSFMKEDK EIISQVLPIL ALEVSNSNYD SESALNKLIE NQNSDGSFGN
KNENKITTTG QALTALSLFK DNSKVKSAID KSVKYLETVK MDNSTVLASA IHGLDSVGVK
IEESKWSDKL NQLIGYQIVD GSFEGRFSYN NPTSFFSEEG TSKALIALQS VISDKNIYEK
LREDYTKIDS ERVISLDEAI NNTLDHYKKE KEISSLEAVS LFSANQDLSN YDTTKLDKSV
INDKSKLSDD YINVASIIAN GDNPKNYEGT NLVKIIASKQ NADGSFGKSI EDTAHGTLAL
EISNGNYNKD QAIDYIIKSQ EENGGFSRPS ILSIFKSDDS DVVTTAIAIN ALATATSEKS
TNSINKAIEY LDKVQLEDGS FESKLSSTSM VISALTNAGL NSDHERWNNI IDEAISYQDK
LDNKGQFKEE KHDVNINDRS TALALLSLSE FKNSKSVVDK LNEKYTKYEE ENTDASLETA
LDRTSKYYKA NYPNNKNSEI DYRAAMSMYL LSEDLSQFKM SEVSSNSIHK YSSINLDQVN
VINAMMQGYD PKNIDGVNWM EIISEKQEPE TGRFSYKLQG GGVSGEAGVN SHAIAMILME
ITNTPYDDEK ALDYLLKHQS SEGGFGAGQK ADDYETGLSL IAISFLEGRF DLEHEKQNAI
SYFKSRQLQN GMFGYSTFDT GNVATSLIAA GEDISSSKWK DIPNKLINLQ IKTGDNAGLF
KPDESDESIR MYDTYTAGLA LAEVKESKSI YHRLYEEYND SKLDRKPIIY AIDKMFKVGD
KLDLISNVTA SDVEDGNITD KIITEHNIPV DSEGNITQAG EYDVIYKVTD SANNTTTKYI
KVTIEEYSNE APVIKVKDIN LKIGDKLDLS RYAVAMDKED GDITNSIKIT QSKEIPVDKD
GRVTTAGEYE VTYSVEDSSN NRSEVTVVLV VYSKENQAPR IIAKDIEGRV GIPLDILKNV
YADDFEDGDL TSDIKISKNT IKMDENNRPT EKGNYEIVYE VTDSGSAKTT KVVNVEILGE
DEDDSDRVVH IPDKNLKRVL EYMIKSDKIT RGDLRKLDVL SLEQQGVYDL TGLEYATNLR
GLSLRFCTEL DNINVLSNMS NLMVLYLDFT SVDNLKPIKE LDKMGVLTMY ASNVSDISPL
ENMVNMEELN IRLCRGINNI EAVKNMKKLS VLSASRNKIK DISALSNLNN LEYISLEDNK
IEDISSLSEN INLKKLYLNN NNIEDISALE HMNNLVEVEI AKNNIKDISA LGNKESINKL
DFSENNVTDI SVLGNISSYN GKNQTYKLDN AKVNYGEDYE LVLGKDTKVI KGKNGDILDP
IGCSPGNMVE NNTKYVIKNI TNSTSSKLRF EEGNGSSLFS VTMMQDINLS STVINNAPTI
KSNGDINITI GEAVEIPKYV TVHDIEDGDN VKLVYNLPGE LKDGIANKVG TYKVDVIAVD
TQGASSTATV KINVNPKMEE INEAPTIQAT DELNINVGKK FNIEKYVSAN DKEDGKDIEL
KYNLPDELSS GVAKKIGTYN VEVKAIDSKG ASAKTNVSIN VQEKETDIKG VYIEEIQDNY
EPLSVKAKTV EGLKLLLKDI TSKHNIKSIE TREDGNFKIY RLYVGNEDKY IDVKIENTKE
FTDILDEIIS NMNPDEENKP GDEENKPGID EETDKDDEPS IDDKPSKNDK PSTNDEVDKE
NNSKDDGNAN KNNPITSDSS ILGYMLGFIG SLGGISILSK RRKK
//
