ID A0A371RKF2_9PROT Unreviewed; 754 AA.
AC A0A371RKF2;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=DX908_12120 {ECO:0000313|EMBL:RFB05945.1};
OS Parvularcula marina.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Parvularculales;
OC Parvularculaceae; Parvularcula.
OX NCBI_TaxID=2292771 {ECO:0000313|EMBL:RFB05945.1, ECO:0000313|Proteomes:UP000264589};
RN [1] {ECO:0000313|EMBL:RFB05945.1, ECO:0000313|Proteomes:UP000264589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SM1705 {ECO:0000313|EMBL:RFB05945.1,
RC ECO:0000313|Proteomes:UP000264589};
RA Sun L.;
RT "Parvularcula sp. SM1705, isolated from surface water of the South Sea
RT China.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RFB05945.1}.
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DR EMBL; QUQO01000001; RFB05945.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A371RKF2; -.
DR InParanoid; A0A371RKF2; -.
DR OrthoDB; 9801651at2; -.
DR Proteomes; UP000264589; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR43047:SF79; HISTIDINE KINASE; 1.
DR PANTHER; PTHR43047; TWO-COMPONENT HISTIDINE PROTEIN KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF12860; PAS_7; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000264589};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 25..45
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 175..197
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 494..713
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT REGION 733..754
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 450..487
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 754 AA; 83476 MW; BBDD9746C03AB139 CRC64;
MQLGLPLKAG IRRFQTLTAP NLGRLTSLTL LLTGACIGML GYAAVEDQQR LTREAALDLS
VRTLTTADRL SPATPVAFGP STPLPQAVRN LLTAGAGDDG GTYLLDLPKG SYVAPAPAPN
ASFDYEMLRA VPATGEARRL KDTRGRTWIA AARPLRGDQR IVSLSPYKKN VFRALMPYLV
ASVSILTLAG LFLAMAARAR RLQAQTEGNR QQLLDRLLGP ERAGCGTWLA DAKGVIFPAA
TLAALGYPRS DEPADYAELR EITHPDDLSA LLGLFLGNGT RTEGVVRFMK ADGDWQMVWI
TSFPPTDCRE GIMIPVSNEG MESRRTDELV MRLRETLEAL PQCFLLWDSV GRLVAWNDTF
VQMFEAHPDD ISEGMTVREL ARVIGIEPHF LYDYFAPPSD GMVEPETEMV FPGDRILKLI
RQRTIGEGWV SIGHDITDMR VEEERRARNE RELQMTVDIL ERSRKDLRQA MRSYENEKLR
AENANRAKSE FLANMSHELR TPLNAIIGFS ELMREELYGP LGHEKYDEYI RDINSSGSHL
LTLIDDILDL SKIEAGKLEL KLGQTDLERS LKEGLRFIEP QLRESGLNLT AMIDHVPSVW
ADARAIKQVF INLLSNAEKF TPRGGSISVT TLVDLTSVTI LVADTGIGMT EEQLHRLGAP
FEMIEDHFAR TKRGTGLGIA LSKSLMEAQN GILAIASEIR RGTVAAITLP RRAGVDVMLP
SMLRDRARIL TKSDKPSRLT APQEGDLPLQ ISAE
//
