ID   A0A371SLF1_9BACI        Unreviewed;       422 AA.
AC   A0A371SLF1;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   24-JAN-2024, entry version 13.
DE   SubName: Full=Mechanosensitive ion channel family protein {ECO:0000313|EMBL:RFB18546.1};
GN   ORFNames=DZB84_06470 {ECO:0000313|EMBL:RFB18546.1};
OS   Bacillus sp. HNG.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=2293325 {ECO:0000313|EMBL:RFB18546.1, ECO:0000313|Proteomes:UP000263943};
RN   [1] {ECO:0000313|EMBL:RFB18546.1, ECO:0000313|Proteomes:UP000263943}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HNG {ECO:0000313|EMBL:RFB18546.1,
RC   ECO:0000313|Proteomes:UP000263943};
RA   Gagnon H.N., Maines B.A., Sevigny J.L.;
RT   "Genome Assembly of Bacillus sp. HNG.";
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RFB18546.1}.
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DR   EMBL; QUQV01000002; RFB18546.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A371SLF1; -.
DR   OrthoDB; 9775207at2; -.
DR   Proteomes; UP000263943; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008381; F:mechanosensitive monoatomic ion channel activity; IEA:InterPro.
DR   GO; GO:0071470; P:cellular response to osmotic stress; IEA:InterPro.
DR   Gene3D; 2.30.30.60; -; 1.
DR   InterPro; IPR010920; LSM_dom_sf.
DR   InterPro; IPR023408; MscS_beta-dom_sf.
DR   InterPro; IPR006685; MscS_channel_2nd.
DR   InterPro; IPR030192; YbdG.
DR   PANTHER; PTHR30414:SF0; MINICONDUCTANCE MECHANOSENSITIVE CHANNEL YBDG; 1.
DR   PANTHER; PTHR30414; UNCHARACTERIZED; 1.
DR   Pfam; PF00924; MS_channel_2nd; 1.
DR   SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000263943};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        20..41
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        98..119
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        140..157
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        163..180
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          182..250
FT                   /note="Mechanosensitive ion channel MscS"
FT                   /evidence="ECO:0000259|Pfam:PF00924"
SQ   SEQUENCE   422 AA;  48159 MW;  260433C6A344EF7A CRC64;
     MKFINRRLLD YGLDPTWAHY LSGVLMILFI ALICIVANFI TKKVIINIIT RIVTKTKYQW
     DNMLLERKVF RRLSHIVPAI IIHRFSTTFP NYEHLIQMGA NTYIIIVGLM VLSSILNAIN
     DMYQTYEVSK TRPIKGYIQV VKIIVITFGI ILIIANLMGK SPLLLLSGIG ALSAVLMLIF
     KDSLLGLVAG VQLTSNDMVR VGDWIEMPKY GADGDVIDIS LVTVKVQNFD KTITTIPSYA
     MISDSFINWR GMQSSGGRRI KRSLFIDTAS ISFCTEEMIE KFKQIQLLSD YITNRELEIE
     EYNIKHEINR NNPVNGRALT NIGVFRAYVG NYLKQHHGIN QEMTLMVRQL APTEHGLPLE
     IYAFTNDVRW AVYETTQADI FDHLFAVAQE FGLRLFQNPS GHDLKTMMLE GKEEGTVREL
     EH
//