ID A0A372EX33_9RHOB Unreviewed; 343 AA.
AC A0A372EX33;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE RecName: Full=3-hydroxyisobutyryl-CoA hydrolase {ECO:0000256|ARBA:ARBA00011915};
DE EC=3.1.2.4 {ECO:0000256|ARBA:ARBA00011915};
GN ORFNames=DZK27_05935 {ECO:0000313|EMBL:RFP89428.1};
OS Rhodobacteraceae bacterium 63075.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae.
OX NCBI_TaxID=2301226 {ECO:0000313|EMBL:RFP89428.1, ECO:0000313|Proteomes:UP000264392};
RN [1] {ECO:0000313|Proteomes:UP000264392}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=63075 {ECO:0000313|Proteomes:UP000264392};
RA Han S.;
RT "Wenzhouxiangella salilacus sp. nov., a novel bacterium isolated from a
RT saline lake in Xinjiang Province, China.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-
CC methylpropanoate + CoA + H(+); Xref=Rhea:RHEA:20888,
CC ChEBI:CHEBI:11805, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57340; EC=3.1.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00001709};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RFP89428.1}.
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DR EMBL; QVMW01000004; RFP89428.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A372EX33; -.
DR OrthoDB; 9790967at2; -.
DR Proteomes; UP000264392; Unassembled WGS sequence.
DR GO; GO:0003860; F:3-hydroxyisobutyryl-CoA hydrolase activity; IEA:InterPro.
DR GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR CDD; cd06558; crotonase-like; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR045004; ECH_dom.
DR InterPro; IPR032259; HIBYL-CoA-H.
DR PANTHER; PTHR43176:SF3; 3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43176; 3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED; 1.
DR Pfam; PF16113; ECH_2; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Isomerase {ECO:0000313|EMBL:RFP89428.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000264392}.
FT DOMAIN 13..320
FT /note="Enoyl-CoA hydratase/isomerase"
FT /evidence="ECO:0000259|Pfam:PF16113"
SQ SEQUENCE 343 AA; 36882 MW; E6C33A8BFD53E69D CRC64;
MSDISIRIEG AAGRITLTRP KALNAVTYEM VTAIHTALDD WREEDSVKLV VIDAEGEKAF
SAGGDIADLY ESGMKGDFAF GQRFWADEYR MNAALHEYEK PVVSFLQGFT MGGGMGVGCH
GSHRVVGESS QVAMPECGIG LVPDVGGSMI LANAPGHTGA YLGTTGTRMG PTEAIYAGFA
DHYIPEAEWP ALISQLELTG DAKLVEMAAT TPPEGTLMPL QDEIDAAFGA GDLRDILQKL
DETDTKFAAS AAKDLRRAAP LSAAATLMMM ERLEGCTDIR EALALEYRFT ARSMEHGDFL
EGIRAAIIDK DRQPRWKHAA GGLKQDEVAA MLAPLGDMEL TFD
//
