ID   A0A372EXQ8_9RHOB        Unreviewed;      1001 AA.
AC   A0A372EXQ8;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   SubName: Full=Sarcosine oxidase subunit alpha family protein {ECO:0000313|EMBL:RFP89790.1};
GN   ORFNames=DZK27_04825 {ECO:0000313|EMBL:RFP89790.1};
OS   Rhodobacteraceae bacterium 63075.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Paracoccaceae.
OX   NCBI_TaxID=2301226 {ECO:0000313|EMBL:RFP89790.1, ECO:0000313|Proteomes:UP000264392};
RN   [1] {ECO:0000313|Proteomes:UP000264392}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=63075 {ECO:0000313|Proteomes:UP000264392};
RA   Han S.;
RT   "Wenzhouxiangella salilacus sp. nov., a novel bacterium isolated from a
RT   saline lake in Xinjiang Province, China.";
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the GcvT family.
CC       {ECO:0000256|ARBA:ARBA00008609}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RFP89790.1}.
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DR   EMBL; QVMW01000003; RFP89790.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A372EXQ8; -.
DR   OrthoDB; 5287468at2; -.
DR   Proteomes; UP000264392; Unassembled WGS sequence.
DR   GO; GO:0008115; F:sarcosine oxidase activity; IEA:InterPro.
DR   GO; GO:0046653; P:tetrahydrofolate metabolic process; IEA:InterPro.
DR   Gene3D; 3.10.20.440; 2Fe-2S iron-sulphur cluster binding domain, sarcosine oxidase, alpha subunit, N-terminal domain; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR042204; 2Fe-2S-bd_N.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR028896; GCST/YgfZ/DmdA.
DR   InterPro; IPR013977; GCV_T_C.
DR   InterPro; IPR006222; GCV_T_N.
DR   InterPro; IPR029043; GcvT/YgfZ_C.
DR   InterPro; IPR006277; Sarcosine_oxidase_asu.
DR   InterPro; IPR041117; SoxA_A3.
DR   InterPro; IPR027266; TrmE/GcvT_dom1.
DR   NCBIfam; TIGR01372; soxA; 1.
DR   PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR   PANTHER; PTHR43757:SF2; AMINOMETHYLTRANSFERASE, MITOCHONDRIAL; 1.
DR   Pfam; PF12831; FAD_oxidored; 1.
DR   Pfam; PF13510; Fer2_4; 1.
DR   Pfam; PF01571; GCV_T; 1.
DR   Pfam; PF08669; GCV_T_C; 1.
DR   Pfam; PF17806; SO_alpha_A3; 1.
DR   PIRSF; PIRSF037980; SoxA; 1.
DR   PRINTS; PR00368; FADPNR.
DR   SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   SUPFAM; SSF103025; Folate-binding domain; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000264392}.
FT   DOMAIN          519..601
FT                   /note="SoxA A3"
FT                   /evidence="ECO:0000259|Pfam:PF17806"
FT   DOMAIN          616..882
FT                   /note="Aminomethyltransferase folate-binding"
FT                   /evidence="ECO:0000259|Pfam:PF01571"
FT   DOMAIN          908..993
FT                   /note="Glycine cleavage T-protein C-terminal barrel"
FT                   /evidence="ECO:0000259|Pfam:PF08669"
SQ   SEQUENCE   1001 AA;  109001 MW;  5CA0299FA2DEB7F2 CRC64;
     MSTRLANGGR RIDRTRPVEF RFNGKRLKGF EGDTLASALL ANDQMMMGRS FKYHRPRGVV
     ASGSEEPNAL FNMGEGGKFE PNQRATTTEL FDGLSVTSQN HWPSLEFDVG VLNNYAARFL
     PAGFYYKTFM FPRPAWKHVF EPFIRQSAGL GRAPDKETLD ADTYEHFYFF ADVVVVGGGV
     AGLQAAKTAA LSGAKVLIME QDPHWGGRAM VDGEPEEGFV QRLVGELEGM DNVTMRRRMM
     GAGVYDHGYL LGYERLRDHA PMLAGPRHRL WRIRAGQIIT ATGAIERPLS FAGNDIPGVM
     LAGAVRDYIA EYGVSPGDRV AVVTNNDDAY RTAIAVKKAG LEVPVIVDAR AGGGGELARE
     ARGMGIRVEN GKAIAKVTGG KRVKSVKLCA QAGEGAVLEE VACDAVAMSG GWSPVVHLWS
     HCGGKLVWDE AEAMFRPDES RPPLNQNGAG FVRCAGAANG ALDLGAGLAD ADAAGKGAAE
     AAGFKARGDT LPDLAQDDAL PIEPVWMMPQ GAGPKLRMKA WLDYQNDVKV SDVQLAAREG
     YESVEHTKRY TTLGMATDQG KLSNINGLAI LSDTLGQAIP QTGTTTFRPP YTPISMASIA
     GEARGEIFQP VRRTPMHAWH EANGAHWEPV GHWRRPYCYL KGEETPHEAV SREIRATRAS
     LGLLDASTLG KLIVKGPDAG KFLDMLYTNM MSTLKPGRCR YGLMCSENGF LSDDGVVVRL
     DEDSFLCHTT TGGAERIHGH MEEWLQTEWW DWQVHVVNAT EQWAQVGVVG PNSRKVLEKL
     GGDVDISKDG LSFMGYTSGK LGEFDARIFR IAFAGELSYE VAVPASQGRA LWDALWDAGE
     EFGVTPYGTE AMHVMRAEKG FIMIGDETDG TVIPQDLGLH WAISKKKEDY IGKRAQERTF
     MQSSDRWQLV GLETVDGSVI PDGAYAVAEG ENANGQRNVQ GRVTSTYYSP TLDRGIAMGL
     VHKGPERMGE VIDFPGTDGT IYKAKIVDAV FYDPEGEKQN V
//