ID   A0A372F164_9BACT        Unreviewed;       696 AA.
AC   A0A372F164;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=HEPN domain-containing protein {ECO:0000313|EMBL:RFS13624.1};
GN   ORFNames=D0T08_25575 {ECO:0000313|EMBL:RFS13624.1};
OS   Emticicia sp. C21.
OC   Bacteria; Bacteroidota; Cytophagia; Cytophagales; Spirosomataceae;
OC   Emticicia.
OX   NCBI_TaxID=2302915 {ECO:0000313|EMBL:RFS13624.1, ECO:0000313|Proteomes:UP000263688};
RN   [1] {ECO:0000313|Proteomes:UP000263688}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C21 {ECO:0000313|Proteomes:UP000263688};
RA   Seo T., Choi J.;
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:RFS13624.1, ECO:0000313|Proteomes:UP000263688}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C21 {ECO:0000313|EMBL:RFS13624.1,
RC   ECO:0000313|Proteomes:UP000263688};
RA   Lis Q.M.;
RT   "Emticicia ginsengisoli sp. nov.,.";
RL   Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RFS13624.1}.
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DR   EMBL; QVMT01000018; RFS13624.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A372F164; -.
DR   OrthoDB; 9803707at2; -.
DR   Proteomes; UP000263688; Unassembled WGS sequence.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.120.330; Nucleotidyltransferases domain 2; 1.
DR   Gene3D; 3.30.413.10; Sulfite Reductase Hemoprotein, domain 1; 2.
DR   Gene3D; 3.90.480.10; Sulfite Reductase Hemoprotein;Domain 2; 1.
DR   InterPro; IPR007842; HEPN_dom.
DR   InterPro; IPR005117; NiRdtase/SiRdtase_haem-b_fer.
DR   InterPro; IPR036136; Nit/Sulf_reduc_fer-like_dom_sf.
DR   InterPro; IPR006067; NO2/SO3_Rdtase_4Fe4S_dom.
DR   InterPro; IPR045854; NO2/SO3_Rdtase_4Fe4S_sf.
DR   InterPro; IPR006066; NO2/SO3_Rdtase_FeS/sirohaem_BS.
DR   PANTHER; PTHR32439:SF9; BLR3264 PROTEIN; 1.
DR   PANTHER; PTHR32439; FERREDOXIN--NITRITE REDUCTASE, CHLOROPLASTIC; 1.
DR   Pfam; PF05168; HEPN; 1.
DR   Pfam; PF01077; NIR_SIR; 2.
DR   Pfam; PF03460; NIR_SIR_ferr; 2.
DR   PRINTS; PR00397; SIROHAEM.
DR   SUPFAM; SSF56014; Nitrite and sulphite reductase 4Fe-4S domain-like; 2.
DR   SUPFAM; SSF55124; Nitrite/Sulfite reductase N-terminal domain-like; 2.
PE   4: Predicted;
KW   Heme {ECO:0000256|ARBA:ARBA00022617}; Iron {ECO:0000256|ARBA:ARBA00022617};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022617};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT   DOMAIN          47..112
FT                   /note="Nitrite/Sulfite reductase ferredoxin-like"
FT                   /evidence="ECO:0000259|Pfam:PF03460"
FT   DOMAIN          122..272
FT                   /note="Nitrite/sulphite reductase 4Fe-4S"
FT                   /evidence="ECO:0000259|Pfam:PF01077"
FT   DOMAIN          320..385
FT                   /note="Nitrite/Sulfite reductase ferredoxin-like"
FT                   /evidence="ECO:0000259|Pfam:PF03460"
FT   DOMAIN          393..538
FT                   /note="Nitrite/sulphite reductase 4Fe-4S"
FT                   /evidence="ECO:0000259|Pfam:PF01077"
FT   DOMAIN          583..655
FT                   /note="HEPN"
FT                   /evidence="ECO:0000259|Pfam:PF05168"
SQ   SEQUENCE   696 AA;  79414 MW;  CD140D867F78A7E7 CRC64;
     MQSFRTELEN PIVQKDIIDL ERKIRLFREG KIHEEKFRSL RLARGVYGQR QQGVQMVRIK
     LPYGKMTLDQ WQRITHISDE YATGNLHLTT RQDIQIHFVS LDRTPELWSK LEQDKITIRE
     ACGNTVRNIT GSATAGIDPK ELFDITPYTH AAFEYFLRNP VCQEMGRKFK IAFSNTDDDT
     AFTFIHDLGF IPKIQNGQRG FKVVLGGGLG AQPQLAYLAY EFLEEDQVIP FIEAVIRVFD
     RYGERTSRHK ARMKFLIAKL GFEEFMKLVE VEKTALKVKT FKVDTEKPQF QYNYPTPEAQ
     EVPEITSEAY KNWYKTNVFA QKQEGYYGIF VRIPLGDISS VVSRSLIEKL RPYIADDVRV
     TVNQGLLFRF VQAKDLPYIF SVLSEYNLAA PGANSIANIT ACPGTDTCNL AISDSTKISL
     EFEKVLREDF PELIEENNIQ IKISGCMNAC GQHSMAQIGF HGSSLKSAGK VLPALQVLLG
     GGVKGNGEGR ISDKVIKVPS KRGPQVLRIV LNDYETNGFD GEYFNDYYDR QGEKYFYALL
     KPLTDLTTLI DTDFVDWGRD EIFQTEIGIG ECASVIIDLV ATLFYESEEK IAWAKDAFNE
     NRWADAIYYA YQSQVNTAKA LLLEKNINSS TQHGVISEFD KNFNEEFGIN FKEQVLQINQ
     NEPSQVFAID YISESENFLK EAMTWREANK TVIVEA
//