ID   A0A372FS97_9ACTN        Unreviewed;       348 AA.
AC   A0A372FS97;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=NAD-dependent epimerase/dehydratase family protein {ECO:0000313|EMBL:RFS43657.1};
GN   ORFNames=D0Q02_26660 {ECO:0000313|EMBL:RFS43657.1};
OS   Micromonospora craniellae.
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Micromonospora.
OX   NCBI_TaxID=2294034 {ECO:0000313|EMBL:RFS43657.1, ECO:0000313|Proteomes:UP000262621};
RN   [1] {ECO:0000313|EMBL:RFS43657.1, ECO:0000313|Proteomes:UP000262621}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LHW63014 {ECO:0000313|EMBL:RFS43657.1,
RC   ECO:0000313|Proteomes:UP000262621};
RA   Li L., Lin H.W.;
RT   "Verrucosispora craniellae sp. nov., isolated from a marine sponge in the
RT   South China Sea.";
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RFS43657.1}.
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DR   EMBL; QVFU01000050; RFS43657.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A372FS97; -.
DR   OrthoDB; 3174087at2; -.
DR   Proteomes; UP000262621; Unassembled WGS sequence.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR001509; Epimerase_deHydtase.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR48079; PROTEIN YEEZ; 1.
DR   PANTHER; PTHR48079:SF6; PROTEIN YEEZ; 1.
DR   Pfam; PF01370; Epimerase; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000262621}.
FT   DOMAIN          3..225
FT                   /note="NAD-dependent epimerase/dehydratase"
FT                   /evidence="ECO:0000259|Pfam:PF01370"
FT   REGION          323..348
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        330..348
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   348 AA;  37140 MW;  51077EAF85413047 CRC64;
     MRILVTGASS MLGSAAATAL RMRGDEVRVL QRRPSGLVGV DEHRGDITDP RVVRAATEGV
     DAVVHLAAKV SMTGPWRQFE HINIGGTATL LAAARAAGVT RFVHVSSPSV AHHGTGLVGA
     EAGAADPDRA RGHYARSKAS AELLALAADS PDFAVVAIRP HLVWGPGDTQ LVGRIVERAQ
     AGRLALVGQG TALIDTTYVD NAADALVAAL DRAPEAGVHG QAFVVTNGEP RTVYELIERI
     CFAAESAPPR LRVPVAAAKA GGTAVERLWS ALRRTEEPPM TRFLAEQLST AHWFDQRRTR
     EALRWSPQVT LDEGFVRLAA AYRQGSRPRG HQQDLGRHRP FGRDDDGG
//