ID A0A372G8E0_9ACTN Unreviewed; 229 AA.
AC A0A372G8E0;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE SubName: Full=Precorrin-8X methylmutase {ECO:0000313|EMBL:RFS81343.1};
DE EC=5.4.99.61 {ECO:0000313|EMBL:RFS81343.1};
GN ORFNames=D0T12_32425 {ECO:0000313|EMBL:RFS81343.1};
OS Actinomadura spongiicola.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Thermomonosporaceae; Actinomadura.
OX NCBI_TaxID=2303421 {ECO:0000313|EMBL:RFS81343.1, ECO:0000313|Proteomes:UP000262882};
RN [1] {ECO:0000313|EMBL:RFS81343.1, ECO:0000313|Proteomes:UP000262882}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LHW52907 {ECO:0000313|EMBL:RFS81343.1,
RC ECO:0000313|Proteomes:UP000262882};
RA Li L., Lin H.W.;
RT "Actinomadura spongicola sp. nov., isolated from marine sponge Leucetta
RT chagosensis.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004953}.
CC -!- SIMILARITY: Belongs to the CobH/CbiC family.
CC {ECO:0000256|ARBA:ARBA00009774}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RFS81343.1}.
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DR EMBL; QVNQ01000014; RFS81343.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A372G8E0; -.
DR OrthoDB; 9780708at2; -.
DR UniPathway; UPA00148; -.
DR Proteomes; UP000262882; Unassembled WGS sequence.
DR GO; GO:0016993; F:precorrin-8X methylmutase activity; IEA:UniProtKB-EC.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.40.50.10230; Cobalamin biosynthesis CobH/CbiC, precorrin-8X methylmutase; 1.
DR InterPro; IPR003722; Cbl_synth_CobH/CbiC.
DR InterPro; IPR036588; CobH/CbiC_sf.
DR PANTHER; PTHR43588; COBALT-PRECORRIN-8 METHYLMUTASE; 1.
DR PANTHER; PTHR43588:SF1; COBALT-PRECORRIN-8 METHYLMUTASE; 1.
DR Pfam; PF02570; CbiC; 1.
DR SUPFAM; SSF63965; Precorrin-8X methylmutase CbiC/CobH; 1.
PE 3: Inferred from homology;
KW Cobalamin biosynthesis {ECO:0000256|ARBA:ARBA00022573};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:RFS81343.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000262882}.
FT DOMAIN 33..226
FT /note="Cobalamin biosynthesis precorrin-8X methylmutase
FT CobH/CbiC"
FT /evidence="ECO:0000259|Pfam:PF02570"
SQ SEQUENCE 229 AA; 23612 MW; E9CCB2C9D1721109 CRC64;
MRPVLRDAAR AGRSEDGGTG RAHVIDYIRD GAEIYRRSFA TIRAEADLSR LPEDVARVAV
RMIHACGMTD LVDDLAWSPG VVERARAALV GGAPILCDAR MVASGVTRAR LPAGNEVVCT
LGDPRVPDLA ARLGTTRSAA ALDLWLDRLD GAVVAIGNAP TALFRLLELV GDGAGRPAAI
LGIPVGFVGA VESKEALGAS GLPHLVVRGR RGGSAIAAAA VNAIASEAE
//
