ID   A0A372G8G6_9ACTN        Unreviewed;       866 AA.
AC   A0A372G8G6;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=AAA family ATPase {ECO:0000313|EMBL:RFS81617.1};
GN   ORFNames=D0T12_30435 {ECO:0000313|EMBL:RFS81617.1};
OS   Actinomadura spongiicola.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Thermomonosporaceae; Actinomadura.
OX   NCBI_TaxID=2303421 {ECO:0000313|EMBL:RFS81617.1, ECO:0000313|Proteomes:UP000262882};
RN   [1] {ECO:0000313|EMBL:RFS81617.1, ECO:0000313|Proteomes:UP000262882}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LHW52907 {ECO:0000313|EMBL:RFS81617.1,
RC   ECO:0000313|Proteomes:UP000262882};
RA   Li L., Lin H.W.;
RT   "Actinomadura spongicola sp. nov., isolated from marine sponge Leucetta
RT   chagosensis.";
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- SIMILARITY: Belongs to the CbxX/CfxQ family.
CC       {ECO:0000256|ARBA:ARBA00010378}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RFS81617.1}.
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DR   EMBL; QVNQ01000012; RFS81617.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A372G8G6; -.
DR   OrthoDB; 9806903at2; -.
DR   Proteomes; UP000262882; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   CDD; cd00009; AAA; 2.
DR   Gene3D; 1.10.8.60; -; 2.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR041627; AAA_lid_6.
DR   InterPro; IPR003959; ATPase_AAA_core.
DR   InterPro; IPR000641; CbxX/CfxQ.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR43392; AAA-TYPE ATPASE FAMILY PROTEIN / ANKYRIN REPEAT FAMILY PROTEIN; 1.
DR   PANTHER; PTHR43392:SF2; AAA-TYPE ATPASE FAMILY PROTEIN _ ANKYRIN REPEAT FAMILY PROTEIN; 1.
DR   Pfam; PF00004; AAA; 2.
DR   Pfam; PF17866; AAA_lid_6; 2.
DR   PRINTS; PR00819; CBXCFQXSUPER.
DR   SMART; SM00382; AAA; 2.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000262882};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        33..52
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        58..76
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        83..103
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        115..131
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          335..476
FT                   /note="AAA+ ATPase"
FT                   /evidence="ECO:0000259|SMART:SM00382"
FT   DOMAIN          629..770
FT                   /note="AAA+ ATPase"
FT                   /evidence="ECO:0000259|SMART:SM00382"
FT   REGION          194..288
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        213..248
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   866 AA;  93035 MW;  57D51B22AFB5EC6B CRC64;
     MALFGRSRSR AAKDAAARDL FERLRWRYFQ VTPGVRFLGG LLLIALVVSA TVVLDGPFLA
     AAAFTAILLV VAHLTLRSPT GMAVVAVITA WLVLSVPLGR LYPDEEHPPY LSPELLLALL
     ALPVAFVAFR LRGYTPWRST LVALGTAGMT TAAVVHPLPE ANVAPGWIAA LIVLGYRWDQ
     ARRTVPAEAY ETGWVQEQAG PKGDGTATSR KNPSGNDKRD RPERVDRAAK DDGPGRPGRP
     DRRAADDAEA GAASAGHAGH DQRVAAQTTD TAEPGRAAPA EPRGEATPEI SVADALAELE
     DMIGLEPVKR QVRSIAASIE AAHMRAAAGV PTEKPMRHFV FVGPSGTGKT TVARVLAKIF
     YAFGLLPEPA LVEAHRADLV GEFLGATALK TNRLVDSALG GVLFVDEAYG LVNSAEGQPD
     RFGDEAVQTL LKRAEDDRDN LVIILAGYDA QMAEFLDSNP GLASRFGTRV HFPSYRPSEL
     LRIADYHVGL REDRFDPEAR RRLAARFEEV ERRGIVDELG NGRFVRSLTE AAARARDVRV
     VNAASGSAGP AAPSADDLVT LRAEDVEAAF AEVTERYRGY AETPTLDEAL RSLDAMIGLE
     PVKRQVREIA AQLQVARMRE EQGLVTRPPT RHFVFTGPPG TGKTTVARVL GRIFAAAGLL
     ARPEVVEAQR ADLVGEHLGA TALKTNKVVD SALGGILFVD EAYALSNPGY SGGDAFGAEA
     VQTLLKRAED DRDRLVIVLA GYETEMDGFL SSNPGLASRF DVRVDFPSYG PDELLRIAQL
     IAEEGGDHWE DRALDDLALV FQRACGSGRI DELGNGRFAR SMYEKACARR ALRAAGLGDA
     ATAADLTVLT ADDVRDAFAE LTHRLG
//