ID A0A372GCQ6_9ACTN Unreviewed; 617 AA.
AC A0A372GCQ6;
DT 07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT 07-NOV-2018, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE RecName: Full=beta-glucosidase {ECO:0000256|ARBA:ARBA00012744};
DE EC=3.2.1.21 {ECO:0000256|ARBA:ARBA00012744};
GN ORFNames=D0T12_25950 {ECO:0000313|EMBL:RFS82863.1};
OS Actinomadura spongiicola.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Thermomonosporaceae; Actinomadura.
OX NCBI_TaxID=2303421 {ECO:0000313|EMBL:RFS82863.1, ECO:0000313|Proteomes:UP000262882};
RN [1] {ECO:0000313|EMBL:RFS82863.1, ECO:0000313|Proteomes:UP000262882}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LHW52907 {ECO:0000313|EMBL:RFS82863.1,
RC ECO:0000313|Proteomes:UP000262882};
RA Li L., Lin H.W.;
RT "Actinomadura spongicola sp. nov., isolated from marine sponge Leucetta
RT chagosensis.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal, non-reducing beta-D-glucosyl residues
CC with release of beta-D-glucose.; EC=3.2.1.21;
CC Evidence={ECO:0000256|ARBA:ARBA00000448};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 3 family.
CC {ECO:0000256|ARBA:ARBA00005336, ECO:0000256|RuleBase:RU361161}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RFS82863.1}.
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DR EMBL; QVNQ01000008; RFS82863.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A372GCQ6; -.
DR OrthoDB; 9803863at2; -.
DR Proteomes; UP000262882; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.1700; Glycoside hydrolase family 3 C-terminal domain; 1.
DR Gene3D; 3.20.20.300; Glycoside hydrolase, family 3, N-terminal domain; 1.
DR InterPro; IPR019800; Glyco_hydro_3_AS.
DR InterPro; IPR002772; Glyco_hydro_3_C.
DR InterPro; IPR036881; Glyco_hydro_3_C_sf.
DR InterPro; IPR001764; Glyco_hydro_3_N.
DR InterPro; IPR036962; Glyco_hydro_3_N_sf.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR30620:SF16; LYSOSOMAL BETA GLUCOSIDASE; 1.
DR PANTHER; PTHR30620; PERIPLASMIC BETA-GLUCOSIDASE-RELATED; 1.
DR Pfam; PF00933; Glyco_hydro_3; 1.
DR Pfam; PF01915; Glyco_hydro_3_C; 1.
DR PRINTS; PR00133; GLHYDRLASE3.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF52279; Beta-D-glucan exohydrolase, C-terminal domain; 1.
DR PROSITE; PS00775; GLYCOSYL_HYDROL_F3; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|RuleBase:RU361161};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361161};
KW Reference proteome {ECO:0000313|Proteomes:UP000262882}.
FT DOMAIN 62..373
FT /note="Glycoside hydrolase family 3 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00933"
FT DOMAIN 412..611
FT /note="Glycoside hydrolase family 3 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF01915"
SQ SEQUENCE 617 AA; 66510 MW; 4CA651FC2EB50748 CRC64;
MPSCMHGFFG KATRSRVVGC GMVVVLALVT CGGRVEPGPA PYMDSRLAVE DRVDDLLDRM
SLDDKLGQMT QPERRYITLQ EITRYRIGSV LSSGGSAPTP NTAKSWADMY DGLQRAALAG
PLGIPLMYGV DAVHGHNTVV GATVFPHNIG LGATRDPRLV REIGAATAKE MAATGVDWNF
APCVCVVRND RWGRTYESFG EVPELPSMMT TVIDGMQDAG PASVLATAKH YLGDGGTEGG
DDRGDTRVSE KELRAVHLPP FRAAVKRGVG SVMISYSSWN GLKMHRHRYL IRDVLKRELG
FTGFVVSDYN GIDQIDGQPG FTKDEVSAAV NAGIDMVMVP AKWRRFIDYL RDAVKAGEVS
MARIDDANRR ILTKKFQLGL FERPMADRSY LTTVGGAAHR KLARRAVAAS QVLLKNDGVL
PLDDEDKIFV AGDSANDIGM QSGGWTITWQ GKAGPITPGT TILDGIRKVA PSASITYGKD
GTGIDGSYDA AVAVVGERPY AEYHGDRTGD LGLDAGDLRT IDRLRDAGVP VVVVLVSGRP
LDIAERLPGW DALVAAWLPG TEGGGVADVL FGRTAPTGRL PVTWMRDGDQ QPINRGDGKR
PLFPFGHGLT YRWLRSG
//
