ID   A0A372GIF3_9ACTN        Unreviewed;       748 AA.
AC   A0A372GIF3;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   24-JAN-2024, entry version 14.
DE   SubName: Full=NACHT domain-containing protein {ECO:0000313|EMBL:RFS84889.1};
GN   ORFNames=D0T12_15375 {ECO:0000313|EMBL:RFS84889.1};
OS   Actinomadura spongiicola.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Thermomonosporaceae; Actinomadura.
OX   NCBI_TaxID=2303421 {ECO:0000313|EMBL:RFS84889.1, ECO:0000313|Proteomes:UP000262882};
RN   [1] {ECO:0000313|EMBL:RFS84889.1, ECO:0000313|Proteomes:UP000262882}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LHW52907 {ECO:0000313|EMBL:RFS84889.1,
RC   ECO:0000313|Proteomes:UP000262882};
RA   Li L., Lin H.W.;
RT   "Actinomadura spongicola sp. nov., isolated from marine sponge Leucetta
RT   chagosensis.";
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RFS84889.1}.
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DR   EMBL; QVNQ01000004; RFS84889.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A372GIF3; -.
DR   OrthoDB; 419058at2; -.
DR   Proteomes; UP000262882; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF05729; NACHT; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS50837; NACHT; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000262882};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        376..394
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        400..420
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        441..466
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        478..502
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        585..608
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          112..228
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|PROSITE:PS50837"
SQ   SEQUENCE   748 AA;  82597 MW;  2249B0BDE8087E56 CRC64;
     MAWRRRSDVV ARFEKQSVAE NRVGGDVALV QQVIVDGRSP EDRAVRLLAE SVDRQLSAEV
     QRQQLERPAP IVLRVRETER PVGPLPGAVS GEVRLDGDTT RMVDLFQGLP DRQLVILGEP
     GAGKSVQATL LAHGLLRARE PDGPVPVLFQ MSSWRPHTMP LEAWMEKRLL EDHPLLGDQE
     MARRLVQGRR VLPVLDGLDE ITAESFRDVI MKLDQALDRG TPFVLTCRAK QYEDAAVEFG
     QRLTRAPVIE IEPVQGDDAI RYLEGAVGDD ERWRPVLDHL RAEPGGTLAE ALTTPLMLFL
     ARVAYSAPGS DPRALLSFTD PADVENHVLE AYLPGVYAEY LYPRYPERKA RRWLATLASG
     PREIRWWNVS SRSAEFASWL LYALGTAWIV WLGWNIWFAI MAAVAVLVAN GWFHVGLLLD
     KVEIVATERE AADPRSHLRR YGLFAALFSG VSGAAVGAAM GAWFGGASID ADSATARGYA
     LAAGLLFGTA TLISTAWGRY LLARCEFVLR GRLPVRLGAF IKDAGERGVL RRPGSVYQFR
     HARVQDVLRA EGPALLDDEP YTVLPPGTPR ARQTAKLIAV PSLRLFAHAC TVGVTLAVLG
     GVFAQVGVDF ESGVKPRGGT NTYCLKDGCA NVDYLSWSLP RGGSATTVFR PGSSFRNAPF
     DGLDGQVRIS GCDDAEISME VRAEGSSPRR RTITEGRWHG VRDWPLPASF EHLTVTFRRL
     DTMPCTARLV WERAGLTTNQ YFQIKERL
//