ID   A0A372GJX2_9ACTN        Unreviewed;       312 AA.
AC   A0A372GJX2;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=EamA family transporter {ECO:0000313|EMBL:RFS85403.1};
GN   ORFNames=D0T12_10210 {ECO:0000313|EMBL:RFS85403.1};
OS   Actinomadura spongiicola.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Thermomonosporaceae; Actinomadura.
OX   NCBI_TaxID=2303421 {ECO:0000313|EMBL:RFS85403.1, ECO:0000313|Proteomes:UP000262882};
RN   [1] {ECO:0000313|EMBL:RFS85403.1, ECO:0000313|Proteomes:UP000262882}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LHW52907 {ECO:0000313|EMBL:RFS85403.1,
RC   ECO:0000313|Proteomes:UP000262882};
RA   Li L., Lin H.W.;
RT   "Actinomadura spongicola sp. nov., isolated from marine sponge Leucetta
RT   chagosensis.";
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RFS85403.1}.
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DR   EMBL; QVNQ01000003; RFS85403.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A372GJX2; -.
DR   OrthoDB; 9787117at2; -.
DR   Proteomes; UP000262882; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR000620; EamA_dom.
DR   PANTHER; PTHR32322; INNER MEMBRANE TRANSPORTER; 1.
DR   PANTHER; PTHR32322:SF2; PROTEIN PAGO; 1.
DR   Pfam; PF00892; EamA; 2.
DR   SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000262882};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        39..58
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        78..96
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        102..123
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        130..149
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        161..183
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        190..208
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        214..239
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        251..270
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        276..296
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          12..148
FT                   /note="EamA"
FT                   /evidence="ECO:0000259|Pfam:PF00892"
FT   DOMAIN          160..293
FT                   /note="EamA"
FT                   /evidence="ECO:0000259|Pfam:PF00892"
SQ   SEQUENCE   312 AA;  31051 MW;  1CCB1B891A894348 CRC64;
     MSPHTSARAR RGGLHILFAA SLWGTTGTVR TFADGSSAFS VAAVRVIVGG LVLFALAAAS
     RRGAGLRRLF RDRRNAPLVG VGAVTIAAYQ TAFFVSAGRA GVAVATIVTI GSAPAFTGAV
     GLVTRRAAPG GRWALATTGA VAGCALLVGG GRDAGTDPAG IALALLSGLS YAVYATVASV
     LITRGEDDRA VTGALFGAAA VPLVPILLTQ PAGWVATVPG ALIALYLGVV TTGGGYLLFA
     RGLRTTPATT ATTLTLAEPA VAAVLGIALL DERLGPVALG GLGLLAVSLV VLVAPVRRRN
     AAERAQAGNE LV
//