ID   A0A372GLX7_9ACTN        Unreviewed;       366 AA.
AC   A0A372GLX7;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   SubName: Full=UDP-N-acetylglucosamine 2-epimerase (Non-hydrolyzing) {ECO:0000313|EMBL:RFS86384.1};
DE            EC=5.1.3.14 {ECO:0000313|EMBL:RFS86384.1};
GN   ORFNames=D0T12_07260 {ECO:0000313|EMBL:RFS86384.1};
OS   Actinomadura spongiicola.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Thermomonosporaceae; Actinomadura.
OX   NCBI_TaxID=2303421 {ECO:0000313|EMBL:RFS86384.1, ECO:0000313|Proteomes:UP000262882};
RN   [1] {ECO:0000313|EMBL:RFS86384.1, ECO:0000313|Proteomes:UP000262882}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LHW52907 {ECO:0000313|EMBL:RFS86384.1,
RC   ECO:0000313|Proteomes:UP000262882};
RA   Li L., Lin H.W.;
RT   "Actinomadura spongicola sp. nov., isolated from marine sponge Leucetta
RT   chagosensis.";
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
CC       {ECO:0000256|RuleBase:RU003513}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RFS86384.1}.
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DR   EMBL; QVNQ01000002; RFS86384.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A372GLX7; -.
DR   OrthoDB; 9803238at2; -.
DR   Proteomes; UP000262882; Unassembled WGS sequence.
DR   GO; GO:0008761; F:UDP-N-acetylglucosamine 2-epimerase activity; IEA:UniProtKB-EC.
DR   CDD; cd03786; GTB_UDP-GlcNAc_2-Epimerase; 1.
DR   Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR   InterPro; IPR003331; UDP_GlcNAc_Epimerase_2_dom.
DR   InterPro; IPR029767; WecB-like.
DR   NCBIfam; TIGR00236; wecB; 1.
DR   PANTHER; PTHR43174; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR   PANTHER; PTHR43174:SF1; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR   Pfam; PF02350; Epimerase_2; 1.
DR   SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE   3: Inferred from homology;
KW   Isomerase {ECO:0000256|RuleBase:RU003513, ECO:0000313|EMBL:RFS86384.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000262882}.
FT   DOMAIN          34..360
FT                   /note="UDP-N-acetylglucosamine 2-epimerase"
FT                   /evidence="ECO:0000259|Pfam:PF02350"
SQ   SEQUENCE   366 AA;  39218 MW;  85EAFEE8135AD06C CRC64;
     MNRREIVLGP IVHVLGARPN FVKAAPVIGA LRAAGAEQAV VHTGQHYDTR MSEIFFDELG
     LPEPDVNLGV GSGGHAAQTA ALMIGLEREF TSRSPALVIV YGDVNSTIAA ALVAAKLHIP
     VAHVEAGLRS FDMSMPEEVN RRLTDQLSDL CLVTSPEAVG HLADEGVAVS RIHLVGNPMI
     DTLLANLDAF DTDAVRRDHD LPERYVLATV HRPANVDDPD TAAALVRHLH GVADLADLVI
     PVHPRGRETL LAAGLDDHDG VHVLEPLGYI DFIAAVRGAA AVVTDSGGLQ EETTILGVPC
     LTVRPNTERP ITITHGTNRL VTFEELVPEA RKVLESDARK ADRRPPLWDG AAGPRIAEVI
     MEYLGE
//