ID   A0A372IF78_9RHOB        Unreviewed;       284 AA.
AC   A0A372IF78;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=Hydroxymethylglutaryl-CoA lyase {ECO:0000313|EMBL:RFU13544.1};
GN   ORFNames=DZD18_06605 {ECO:0000313|EMBL:RFU13544.1};
OS   Rhodobacteraceae bacterium W635.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Paracoccaceae.
OX   NCBI_TaxID=2303578 {ECO:0000313|EMBL:RFU13544.1, ECO:0000313|Proteomes:UP000264655};
RN   [1] {ECO:0000313|EMBL:RFU13544.1, ECO:0000313|Proteomes:UP000264655}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=W635 {ECO:0000313|EMBL:RFU13544.1,
RC   ECO:0000313|Proteomes:UP000264655};
RA   Hou X.J.;
RT   "Ayaqqumibacter halotolerans gen. nov., sp. nov., isolated from a saline
RT   lake in Xinjiang province, China.";
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the HMG-CoA lyase family.
CC       {ECO:0000256|ARBA:ARBA00009405}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RFU13544.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; QVQC01000032; RFU13544.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A372IF78; -.
DR   OrthoDB; 9784013at2; -.
DR   Proteomes; UP000264655; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016833; F:oxo-acid-lyase activity; IEA:InterPro.
DR   CDD; cd07938; DRE_TIM_HMGL; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR043594; HMGL.
DR   InterPro; IPR000891; PYR_CT.
DR   PANTHER; PTHR42738; HYDROXYMETHYLGLUTARYL-COA LYASE; 1.
DR   PANTHER; PTHR42738:SF7; HYDROXYMETHYLGLUTARYL-COA LYASE; 1.
DR   Pfam; PF00682; HMGL-like; 1.
DR   SUPFAM; SSF51569; Aldolase; 1.
DR   PROSITE; PS50991; PYR_CT; 1.
PE   3: Inferred from homology;
KW   Lyase {ECO:0000313|EMBL:RFU13544.1};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000264655}.
FT   DOMAIN          5..272
FT                   /note="Pyruvate carboxyltransferase"
FT                   /evidence="ECO:0000259|PROSITE:PS50991"
SQ   SEQUENCE   284 AA;  29469 MW;  EE0852A3C9BDC8E3 CRC64;
     MSDPVEIFEV GPRDGLQNEA RQIPTAEKVA LVDCLGRAGF HRIEVASFVS PKWVPQMADS
     AQVLAGITRA PGVSYAALTP NMQGYERAKE ARADEIAIFA SASEGFSKAN INATIEESIT
     RFVPVAQAAR ADGIPVRGYI SCVTDCPFDG PVAPGDVARV AATLRNMGCY EISLGDTIGQ
     GRPETVDAML AAVLECCAPE ELAGHFHDTG GKALANIEVS LARGLRVFDA AVGGLGGCPY
     APGAAGNVAT EAVAARLAEL GHETGLDQTV LAEASAMARA MRKG
//