ID   A0A372J693_9ACTN        Unreviewed;       161 AA.
AC   A0A372J693;
DT   07-NOV-2018, integrated into UniProtKB/TrEMBL.
DT   07-NOV-2018, sequence version 1.
DT   24-JAN-2024, entry version 14.
DE   RecName: Full=3'-5' exoribonuclease {ECO:0000256|HAMAP-Rule:MF_00977};
DE            EC=3.1.13.- {ECO:0000256|HAMAP-Rule:MF_00977};
GN   ORFNames=D0Z06_04645 {ECO:0000313|EMBL:RFU22539.1};
OS   Geodermatophilus sp. LHW52908.
OC   Bacteria; Actinomycetota; Actinomycetes; Geodermatophilales;
OC   Geodermatophilaceae; Geodermatophilus.
OX   NCBI_TaxID=2303986 {ECO:0000313|EMBL:RFU22539.1, ECO:0000313|Proteomes:UP000262362};
RN   [1] {ECO:0000313|EMBL:RFU22539.1, ECO:0000313|Proteomes:UP000262362}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LHW52908 {ECO:0000313|EMBL:RFU22539.1,
RC   ECO:0000313|Proteomes:UP000262362};
RA   Li L., Lin H.W.;
RT   "Geodermatophilus marinus sp. nov., isolated from marine sponge Leucetta
RT   chagosensis.";
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Exonuclease that cleaves single-stranded 3' overhangs of
CC       double-stranded RNA. {ECO:0000256|HAMAP-Rule:MF_00977}.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|HAMAP-Rule:MF_00977};
CC       Note=Binds 1 Mg(2+) ion per subunit. {ECO:0000256|HAMAP-Rule:MF_00977};
CC   -!- SUBUNIT: Homodimer. {ECO:0000256|HAMAP-Rule:MF_00977}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RFU22539.1}.
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DR   EMBL; QVQH01000003; RFU22539.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A372J693; -.
DR   OrthoDB; 4640719at2; -.
DR   Proteomes; UP000262362; Unassembled WGS sequence.
DR   GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0004532; F:RNA exonuclease activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR   HAMAP; MF_00977; 3_5_Exoribonuc_actinobact; 1.
DR   InterPro; IPR030853; 3_5_Exoribonuc_actinobac.
DR   InterPro; IPR036397; RNaseH_sf.
DR   InterPro; IPR033390; Rv2179c-like.
DR   NCBIfam; NF033638; RNase_AS; 1.
DR   Pfam; PF16473; Rv2179c-like; 1.
PE   3: Inferred from homology;
KW   Exonuclease {ECO:0000256|HAMAP-Rule:MF_00977};
KW   Hydrolase {ECO:0000256|HAMAP-Rule:MF_00977};
KW   Magnesium {ECO:0000256|HAMAP-Rule:MF_00977};
KW   Metal-binding {ECO:0000256|HAMAP-Rule:MF_00977};
KW   Nuclease {ECO:0000256|HAMAP-Rule:MF_00977};
KW   Reference proteome {ECO:0000313|Proteomes:UP000262362}.
FT   DOMAIN          3..154
FT                   /note="3'-5' exoribonuclease Rv2179c-like"
FT                   /evidence="ECO:0000259|Pfam:PF16473"
FT   REGION          7..10
FT                   /note="RNA binding"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_00977"
FT   BINDING         7
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /ligand_note="catalytic"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_00977"
SQ   SEQUENCE   161 AA;  18642 MW;  5C4513F375A237DB CRC64;
     MRRYFYDTEF IEDGTTIDLV SIGVVDEAGR EFYAVSTEFD ERRAIPWVRR NVLDQLPPPA
     DRAWRSRRRI REDLLAFLTG PGEEVELWAW FGAYDHVALC QLWGPMTALP RAVPRFTREL
     RQRWDDRGQP ALPPKPAGSH DALVDARYNL ARWRAMEPGG G
//